These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 9448722)

  • 1. Cloning and expression of CYP2F3, a cytochrome P450 that bioactivates the selective pneumotoxins 3-methylindole and naphthalene.
    Wang H; Lanza DL; Yost GS
    Arch Biochem Biophys; 1998 Jan; 349(2):329-40. PubMed ID: 9448722
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism-based inactivation of lung-selective cytochrome P450 CYP2F enzymes.
    Kartha JS; Yost GS
    Drug Metab Dispos; 2008 Jan; 36(1):155-62. PubMed ID: 17962375
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells.
    Lanza DL; Code E; Crespi CL; Gonzalez FJ; Yost GS
    Drug Metab Dispos; 1999 Jul; 27(7):798-803. PubMed ID: 10383923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Single mutations change CYP2F3 from a dehydrogenase of 3-methylindole to an oxygenase.
    Kartha JS; Skordos KW; Sun H; Hall C; Easterwood LM; Reilly CA; Johnson EF; Yost GS
    Biochemistry; 2008 Sep; 47(37):9756-70. PubMed ID: 18717595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of pulmonary CYP4B2, specific catalyst of methyl oxidation of 3-methylindole.
    Carr BA; Ramakanth S; Dannan GA; Yost GS
    Mol Pharmacol; 2003 May; 63(5):1137-47. PubMed ID: 12695542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent mutagenicity of 3-methylindole requires pulmonary cytochrome P450-mediated bioactivation: a comparison to the prototype cigarette smoke mutagens B(a)P and NNK.
    Weems JM; Lamb JG; D'Agostino J; Ding X; Yost GS
    Chem Res Toxicol; 2010 Nov; 23(11):1682-90. PubMed ID: 20795680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole.
    Skiles GL; Yost GS
    Chem Res Toxicol; 1996; 9(1):291-7. PubMed ID: 8924606
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models.
    Zhou X; D'Agostino J; Li L; Moore CD; Yost GS; Ding X
    Drug Metab Dispos; 2012 Apr; 40(4):642-7. PubMed ID: 22228748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective dehydrogenation/oxygenation of 3-methylindole by cytochrome p450 enzymes.
    Lanza DL; Yost GS
    Drug Metab Dispos; 2001 Jul; 29(7):950-3. PubMed ID: 11408359
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Correlation between pulmonary cytochrome P450 transcripts and the organ-selective pneumotoxicity of 3-methylindole.
    Ramakanth S; Thornton-Manning JR; Wang H; Maxwell H; Yost GS
    Toxicol Lett; 1994 Mar; 71(1):77-85. PubMed ID: 8140592
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively.
    Weems JM; Yost GS
    Chem Res Toxicol; 2010 Mar; 23(3):696-704. PubMed ID: 20187624
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Directed evolution reveals requisite sequence elements in the functional expression of P450 2F1 in Escherichia coli.
    Behrendorff JB; Moore CD; Kim KH; Kim DH; Smith CA; Johnston WA; Yun CH; Yost GS; Gillam EM
    Chem Res Toxicol; 2012 Sep; 25(9):1964-74. PubMed ID: 22901340
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic activation of the pneumotoxin, 3-methylindole, by vaccinia-expressed cytochrome P450s.
    Thornton-Manning JR; Ruangyuttikarn W; Gonzalez FJ; Yost GS
    Biochem Biophys Res Commun; 1991 Nov; 181(1):100-7. PubMed ID: 1958177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of 3-methylindole in human tissues.
    Ruangyuttikarn W; Appleton ML; Yost GS
    Drug Metab Dispos; 1991; 19(5):977-84. PubMed ID: 1686246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Production and characterization of specific antibodies: utilization to predict organ- and species-selective pneumotoxicity of 3-methylindole.
    Kaster JK; Yost GS
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):324-37. PubMed ID: 9144449
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bioactivation of 3-methylindole by isolated rabbit lung cells.
    Nichols WK; Larson DN; Yost GS
    Toxicol Appl Pharmacol; 1990 Sep; 105(2):264-70. PubMed ID: 2219119
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.
    Thornton-Manning J; Appleton ML; Gonzalez FJ; Yost GS
    J Pharmacol Exp Ther; 1996 Jan; 276(1):21-9. PubMed ID: 8558432
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bioactivation of the pulmonary toxicants naphthalene and 1-nitronaphthalene by rat CYP2F4.
    Baldwin RM; Shultz MA; Buckpitt AR
    J Pharmacol Exp Ther; 2005 Feb; 312(2):857-65. PubMed ID: 15509722
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and alpha-methylbenzylaminobenzotriazole.
    Huijzer JC; Adams JD; Jaw JY; Yost GS
    Drug Metab Dispos; 1989; 17(1):37-42. PubMed ID: 2566467
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1.
    Sheets PL; Yost GS; Carlson GP
    J Biochem Mol Toxicol; 2004; 18(2):92-9. PubMed ID: 15122651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.