BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 9449636)

  • 1. Nuclear corepressors enhance the dominant negative activity of mutant receptors that cause resistance to thyroid hormone.
    Tagami T; Jameson JL
    Endocrinology; 1998 Feb; 139(2):640-50. PubMed ID: 9449636
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone.
    Tagami T; Madison LD; Nagaya T; Jameson JL
    Mol Cell Biol; 1997 May; 17(5):2642-8. PubMed ID: 9111334
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors.
    Liu Y; Takeshita A; Misiti S; Chin WW; Yen PM
    Endocrinology; 1998 Oct; 139(10):4197-204. PubMed ID: 9751500
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators.
    Tagami T; Gu WX; Peairs PT; West BL; Jameson JL
    Mol Endocrinol; 1998 Dec; 12(12):1888-902. PubMed ID: 9849963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity.
    Yagi H; Pohlenz J; Hayashi Y; Sakurai A; Refetoff S
    J Clin Endocrinol Metab; 1997 May; 82(5):1608-14. PubMed ID: 9141558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L; Forrest D; Haugen BR; Wood WM; Curran T
    Mol Endocrinol; 1995 Sep; 9(9):1202-13. PubMed ID: 7491112
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Requirement of corepressor binding of thyroid hormone receptor mutants for dominant negative inhibition.
    Nagaya T; Fujieda M; Seo H
    Biochem Biophys Res Commun; 1998 Jun; 247(3):620-3. PubMed ID: 9647743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.
    Safer JD; Cohen RN; Hollenberg AN; Wondisford FE
    J Biol Chem; 1998 Nov; 273(46):30175-82. PubMed ID: 9804773
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dominant negative and DNA-binding properties of mutant thyroid hormone receptors that are defective in homodimerization but not heterodimerization.
    Kitajima K; Nagaya T; Jameson JL
    Thyroid; 1995 Oct; 5(5):343-53. PubMed ID: 8563470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel TR beta mutation (R383H) in resistance to thyroid hormone syndrome predominantly impairs corepressor release and negative transcriptional regulation.
    Clifton-Bligh RJ; de Zegher F; Wagner RL; Collingwood TN; Francois I; Van Helvoirt M; Fletterick RJ; Chatterjee VK
    Mol Endocrinol; 1998 May; 12(5):609-21. PubMed ID: 9605924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation.
    Nomura Y; Nagaya T; Tsukaguchi H; Takamatsu J; Seo H
    Endocrinology; 1996 Oct; 137(10):4082-6. PubMed ID: 8828460
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isoform variable action among thyroid hormone receptor mutants provides insight into pituitary resistance to thyroid hormone.
    Safer JD; Langlois MF; Cohen R; Monden T; John-Hope D; Madura J; Hollenberg AN; Wondisford FE
    Mol Endocrinol; 1997 Jan; 11(1):16-26. PubMed ID: 8994184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spectrum of transcriptional, dimerization, and dominant negative properties of twenty different mutant thyroid hormone beta-receptors in thyroid hormone resistance syndrome.
    Collingwood TN; Adams M; Tone Y; Chatterjee VK
    Mol Endocrinol; 1994 Sep; 8(9):1262-77. PubMed ID: 7838159
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ; Ortiz MA; Pfahl M
    Mol Endocrinol; 1995 Nov; 9(11):1533-48. PubMed ID: 8584031
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors.
    Yoh SM; Chatterjee VK; Privalsky ML
    Mol Endocrinol; 1997 Apr; 11(4):470-80. PubMed ID: 9092799
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
    Wong R; Zhu XG; Pineda MA; Cheng SY; Weintraub BD
    Mol Med; 1995 Mar; 1(3):306-19. PubMed ID: 8529109
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.
    Zhang XY; Kaneshige M; Kamiya Y; Kaneshige K; McPhie P; Cheng SY
    Mol Endocrinol; 2002 Sep; 16(9):2077-92. PubMed ID: 12198244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Very strong correlation between dominant negative activities of mutant thyroid hormone receptors and their binding avidity for corepressor SMRT.
    Matsushita A; Misawa H; Andoh S; Natsume H; Nishiyama K; Sasaki S; Nakamura H
    J Endocrinol; 2000 Dec; 167(3):493-503. PubMed ID: 11115777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pathological Interactions Between Mutant Thyroid Hormone Receptors and Corepressors and Their Modulation by a Thyroid Hormone Analogue with Therapeutic Potential.
    Harrus D; Déméné H; Vasquez E; Boulahtouf A; Germain P; Figueira AC; Privalsky ML; Bourguet W; le Maire A
    Thyroid; 2018 Dec; 28(12):1708-1722. PubMed ID: 30235988
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone.
    Wu SY; Cohen RN; Simsek E; Senses DA; Yar NE; Grasberger H; Noel J; Refetoff S; Weiss RE
    J Clin Endocrinol Metab; 2006 May; 91(5):1887-95. PubMed ID: 16464943
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.