BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 9452492)

  • 1. Casein kinase II stabilizes the activity of human topoisomerase IIalpha in a phosphorylation-independent manner.
    Redwood C; Davies SL; Wells NJ; Fry AM; Hickson ID
    J Biol Chem; 1998 Feb; 273(6):3635-42. PubMed ID: 9452492
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIalpha.
    Aoyama M; Grabowski DR; Dubyak GR; Constantinou AI; Rybicki LA; Bukowski RM; Ganapathi MK; Hickson ID; Ganapathi R
    Biochem J; 1998 Dec; 336 ( Pt 3)(Pt 3):727-33. PubMed ID: 9841887
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation-independent stimulation of DNA topoisomerase II alpha activity.
    Kimura K; Saijo M; Tanaka M; Enomoto T
    J Biol Chem; 1996 May; 271(18):10990-5. PubMed ID: 8631919
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate specificity plays an important role in uncoupling the catalytic and scaffolding activities of rat testis DNA topoisomerase IIalpha.
    Bakshi R; Galande S; Muniyappa K
    J Biomol Struct Dyn; 2001 Apr; 18(5):749-60. PubMed ID: 11334111
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.
    Grozav AG; Chikamori K; Kozuki T; Grabowski DR; Bukowski RM; Willard B; Kinter M; Andersen AH; Ganapathi R; Ganapathi MK
    Nucleic Acids Res; 2009 Feb; 37(2):382-92. PubMed ID: 19043076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Treatment of U937 cells with bufalin induces the translocation of casein kinase 2 and modulates the activity of topoisomerase II prior to the induction of apoptosis.
    Watabe M; Nakajo S; Yoshida T; Kuroiwa Y; Nakaya K
    Cell Growth Differ; 1997 Aug; 8(8):871-9. PubMed ID: 9269896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association of human DNA topoisomerase IIalpha with mitotic chromosomes in mammalian cells is independent of its catalytic activity.
    Mo YY; Beck WT
    Exp Cell Res; 1999 Oct; 252(1):50-62. PubMed ID: 10502399
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Threonine 1342 in human topoisomerase IIalpha is phosphorylated throughout the cell cycle.
    Ishida R; Iwai M; Marsh KL; Austin CA; Yano T; Shibata M; Nozaki N; Hara A
    J Biol Chem; 1996 Nov; 271(47):30077-82. PubMed ID: 8939955
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitotic phosphorylation of DNA topoisomerase II alpha by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469.
    Escargueil AE; Plisov SY; Filhol O; Cochet C; Larsen AK
    J Biol Chem; 2000 Nov; 275(44):34710-8. PubMed ID: 10942766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinoic acid and phorbol ester induced hyperphosphorylation of topoisomerase II-alpha is an early event in HL-60 human leukaemia cell differentiation: effect on topoisomerase activity and etoposide sensitivity.
    Chresta CM; Hall BF; Francis GE
    Leukemia; 1995 Aug; 9(8):1373-81. PubMed ID: 7643627
    [TBL] [Abstract][Full Text] [Related]  

  • 11. UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels.
    Mann MJ; Pereira ER; Liao N; Hendershot LM
    PLoS One; 2012; 7(10):e47931. PubMed ID: 23144714
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of DNA topoisomerase II alpha/beta heterodimers in HeLa cells.
    Gromova I; Biersack H; Jensen S; Nielsen OF; Westergaard O; Andersen AH
    Biochemistry; 1998 Nov; 37(47):16645-52. PubMed ID: 9843432
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.
    Chikamori K; Grabowski DR; Kinter M; Willard BB; Yadav S; Aebersold RH; Bukowski RM; Hickson ID; Andersen AH; Ganapathi R; Ganapathi MK
    J Biol Chem; 2003 Apr; 278(15):12696-702. PubMed ID: 12569090
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.
    Salmena L; Lam V; McPherson JP; Goldenberg GJ
    Biochem Pharmacol; 2001 Apr; 61(7):795-802. PubMed ID: 11274964
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.
    Kozuki T; Chikamori K; Surleac MD; Micluta MA; Petrescu AJ; Norris EJ; Elson P; Hoeltge GA; Grabowski DR; Porter ACG; Ganapathi RN; Ganapathi MK
    Nucleic Acids Res; 2017 Jun; 45(10):5995-6010. PubMed ID: 28472494
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human breast cancer cells.
    Zhou Z; Zwelling LA; Kawakami Y; An T; Kobayashi K; Herzog C; Kleinerman ES
    Cancer Res; 1999 Sep; 59(18):4618-24. PubMed ID: 10493516
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
    Qin Y; Meng L; Hu C; Duan W; Zuo Z; Lin L; Zhang X; Ding J
    Mol Cancer Ther; 2007 Sep; 6(9):2429-40. PubMed ID: 17876042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Casein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody.
    Daum JR; Gorbsky GJ
    J Biol Chem; 1998 Nov; 273(46):30622-9. PubMed ID: 9804834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homologous and heterologous protein-protein interactions of human DNA topoisomerase IIalpha.
    Kroll DJ
    Arch Biochem Biophys; 1997 Sep; 345(2):175-84. PubMed ID: 9308887
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Catalytic inhibition of DNA topoisomerase IIalpha by sodium azide.
    Ju R; Mao Y; Glick MJ; Muller MT; Snyder RD
    Toxicol Lett; 2001 Apr; 121(2):119-26. PubMed ID: 11325562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.