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3. Involvement of the "occluded nucleotide conformation" of P-glycoprotein in the catalytic pathway. Tombline G; Muharemagić A; White LB; Senior AE Biochemistry; 2005 Sep; 44(38):12879-86. PubMed ID: 16171403 [TBL] [Abstract][Full Text] [Related]
4. Stoichiometry and affinity of nucleotide binding to P-glycoprotein during the catalytic cycle. Qu Q; Russell PL; Sharom FJ Biochemistry; 2003 Feb; 42(4):1170-7. PubMed ID: 12549939 [TBL] [Abstract][Full Text] [Related]
5. Drug binding and nucleotide hydrolyzability are essential requirements in the vanadate-induced inhibition of the human P-glycoprotein ATPase. Rao US Biochemistry; 1998 Oct; 37(42):14981-8. PubMed ID: 9778376 [TBL] [Abstract][Full Text] [Related]
6. Proximity of the nucleotide binding domains of the P-glycoprotein multidrug transporter to the membrane surface: a resonance energy transfer study. Liu R; Sharom FJ Biochemistry; 1998 May; 37(18):6503-12. PubMed ID: 9572868 [TBL] [Abstract][Full Text] [Related]
7. Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains. Liu R; Sharom FJ Biochemistry; 1996 Sep; 35(36):11865-73. PubMed ID: 8794769 [TBL] [Abstract][Full Text] [Related]
9. Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites. Sankaran B; Bhagat S; Senior AE Arch Biochem Biophys; 1997 May; 341(1):160-9. PubMed ID: 9143365 [TBL] [Abstract][Full Text] [Related]
10. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Ramachandra M; Ambudkar SV; Chen D; Hrycyna CA; Dey S; Gottesman MM; Pastan I Biochemistry; 1998 Apr; 37(14):5010-9. PubMed ID: 9538020 [TBL] [Abstract][Full Text] [Related]
11. Residues in P-glycoprotein catalytic sites that react with the inhibitor 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole. Senior AE; Gros P; Urbatsch IL Arch Biochem Biophys; 1998 Sep; 357(1):121-5. PubMed ID: 9721190 [TBL] [Abstract][Full Text] [Related]
12. P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site. Urbatsch IL; Sankaran B; Weber J; Senior AE J Biol Chem; 1995 Aug; 270(33):19383-90. PubMed ID: 7642618 [TBL] [Abstract][Full Text] [Related]
13. FRET analysis indicates that the two ATPase active sites of the P-glycoprotein multidrug transporter are closely associated. Qu Q; Sharom FJ Biochemistry; 2001 Feb; 40(5):1413-22. PubMed ID: 11170469 [TBL] [Abstract][Full Text] [Related]
15. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein. Maki N; Moitra K; Silver C; Ghosh P; Chattopadhyay A; Dey S Biochemistry; 2006 Feb; 45(8):2739-51. PubMed ID: 16489767 [TBL] [Abstract][Full Text] [Related]
16. The catalytic cycle of P-glycoprotein. Senior AE; al-Shawi MK; Urbatsch IL FEBS Lett; 1995 Dec; 377(3):285-9. PubMed ID: 8549739 [TBL] [Abstract][Full Text] [Related]
17. Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites. Urbatsch IL; Beaudet L; Carrier I; Gros P Biochemistry; 1998 Mar; 37(13):4592-602. PubMed ID: 9521779 [TBL] [Abstract][Full Text] [Related]
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19. The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids. Eckford PD; Sharom FJ Biochem J; 2005 Jul; 389(Pt 2):517-26. PubMed ID: 15799713 [TBL] [Abstract][Full Text] [Related]
20. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state. Tombline G; Donnelly DJ; Holt JJ; You Y; Ye M; Gannon MK; Nygren CL; Detty MR Biochemistry; 2006 Jul; 45(26):8034-47. PubMed ID: 16800628 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]