234 related articles for article (PubMed ID: 9461564)
1. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.
Cover CM; Hsieh SJ; Tran SH; Hallden G; Kim GS; Bjeldanes LF; Firestone GL
J Biol Chem; 1998 Feb; 273(7):3838-47. PubMed ID: 9461564
[TBL] [Abstract][Full Text] [Related]
2. Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.
Cover CM; Hsieh SJ; Cram EJ; Hong C; Riby JE; Bjeldanes LF; Firestone GL
Cancer Res; 1999 Mar; 59(6):1244-51. PubMed ID: 10096555
[TBL] [Abstract][Full Text] [Related]
3. A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.
Brandi G; Paiardini M; Cervasi B; Fiorucci C; Filippone P; De Marco C; Zaffaroni N; Magnani M
Cancer Res; 2003 Jul; 63(14):4028-36. PubMed ID: 12874002
[TBL] [Abstract][Full Text] [Related]
4. Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells.
Zhang J; Hsu B A JC; Kinseth B A MA; Bjeldanes LF; Firestone GL
Cancer; 2003 Dec; 98(11):2511-20. PubMed ID: 14635088
[TBL] [Abstract][Full Text] [Related]
5. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
Chinni SR; Li Y; Upadhyay S; Koppolu PK; Sarkar FH
Oncogene; 2001 May; 20(23):2927-36. PubMed ID: 11420705
[TBL] [Abstract][Full Text] [Related]
6. 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.
Nguyen HH; Lavrenov SN; Sundar SN; Nguyen DH; Tseng M; Marconett CN; Kung J; Staub RE; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
Chem Biol Interact; 2010 Aug; 186(3):255-66. PubMed ID: 20570586
[TBL] [Abstract][Full Text] [Related]
7. Indole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter.
Cram EJ; Liu BD; Bjeldanes LF; Firestone GL
J Biol Chem; 2001 Jun; 276(25):22332-40. PubMed ID: 11297539
[TBL] [Abstract][Full Text] [Related]
8. N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells.
Jump SM; Kung J; Staub R; Kinseth MA; Cram EJ; Yudina LN; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
Biochem Pharmacol; 2008 Feb; 75(3):713-24. PubMed ID: 18023427
[TBL] [Abstract][Full Text] [Related]
9. Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
Marconett CN; Sundar SN; Tseng M; Tin AS; Tran KQ; Mahuron KM; Bjeldanes LF; Firestone GL
Carcinogenesis; 2011 Sep; 32(9):1315-23. PubMed ID: 21693539
[TBL] [Abstract][Full Text] [Related]
10. Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions.
Firestone GL; Bjeldanes LF
J Nutr; 2003 Jul; 133(7 Suppl):2448S-2455S. PubMed ID: 12840223
[TBL] [Abstract][Full Text] [Related]
11. 3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression.
Hong C; Kim HA; Firestone GL; Bjeldanes LF
Carcinogenesis; 2002 Aug; 23(8):1297-305. PubMed ID: 12151347
[TBL] [Abstract][Full Text] [Related]
12. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
[TBL] [Abstract][Full Text] [Related]
13. Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.
Aggarwal BB; Ichikawa H
Cell Cycle; 2005 Sep; 4(9):1201-15. PubMed ID: 16082211
[TBL] [Abstract][Full Text] [Related]
14. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
Aronchik I; Chen T; Durkin KA; Horwitz MS; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
Mol Carcinog; 2012 Nov; 51(11):881-94. PubMed ID: 22012859
[TBL] [Abstract][Full Text] [Related]
15. Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein.
Hsu JC; Dev A; Wing A; Brew CT; Bjeldanes LF; Firestone GL
Biochem Pharmacol; 2006 Dec; 72(12):1714-23. PubMed ID: 16970927
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
Liang YC; Lin-Shiau SY; Chen CF; Lin JK
J Cell Biochem; 1999 Oct; 75(1):1-12. PubMed ID: 10462699
[TBL] [Abstract][Full Text] [Related]
17. The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing.
Nguyen HH; Aronchik I; Brar GA; Nguyen DH; Bjeldanes LF; Firestone GL
Proc Natl Acad Sci U S A; 2008 Dec; 105(50):19750-5. PubMed ID: 19064917
[TBL] [Abstract][Full Text] [Related]
18. Indole-3-carbinol (I3C) inhibits cyclin-dependent kinase-2 function in human breast cancer cells by regulating the size distribution, associated cyclin E forms, and subcellular localization of the CDK2 protein complex.
Garcia HH; Brar GA; Nguyen DH; Bjeldanes LF; Firestone GL
J Biol Chem; 2005 Mar; 280(10):8756-64. PubMed ID: 15611077
[TBL] [Abstract][Full Text] [Related]
19. Down-regulation of cyclin-dependent kinase-4 and MAPK through estrogen receptor mediated cell cycle arrest in human breast cancer induced by gold nanoparticle tagged toxin protein NKCT1.
Bhowmik T; Gomes A
Chem Biol Interact; 2017 Apr; 268():119-128. PubMed ID: 28322778
[TBL] [Abstract][Full Text] [Related]
20. EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells.
Moiseeva EP; Heukers R; Manson MM
Carcinogenesis; 2007 Feb; 28(2):435-45. PubMed ID: 16956907
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]