These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 9464365)

  • 21. QSAR analysis of some 5-amino-2-mercapto-1,3,4-thiadiazole based inhibitors of matrix metalloproteinases and bacterial collagenase.
    Jamloki A; Karthikeyan C; Hari Narayana Moorthy NS; Trivedi P
    Bioorg Med Chem Lett; 2006 Jul; 16(14):3847-54. PubMed ID: 16682189
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Computer-aided design and synthesis of nonpeptidic plasmepsin II and IV inhibitors.
    Luksch T; Chan NS; Brass S; Sotriffer CA; Klebe G; Diederich WE
    ChemMedChem; 2008 Sep; 3(9):1323-36. PubMed ID: 18752222
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Diverse modes of reactivity of dialkyl azodicarboxylates with P(III) compounds: synthesis, structure, and reactivity of products other than the Morrison-Brunn-Huisgen intermediate in a Mitsunobu-type reaction.
    Satish Kumar N; Praveen Kumar K; Pavan Kumar KV; Kommana P; Vittal JJ; Kumara Swamy KC
    J Org Chem; 2004 Mar; 69(6):1880-9. PubMed ID: 15058933
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides.
    Tuccinardi T; Martinelli A; Nuti E; Carelli P; Balzano F; Uccello-Barretta G; Murphy G; Rossello A
    Bioorg Med Chem; 2006 Jun; 14(12):4260-76. PubMed ID: 16483784
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and SAR of highly selective MMP-13 inhibitors.
    Li J; Rush TS; Li W; DeVincentis D; Du X; Hu Y; Thomason JR; Xiang JS; Skotnicki JS; Tam S; Cunningham KM; Chockalingam PS; Morris EA; Levin JI
    Bioorg Med Chem Lett; 2005 Nov; 15(22):4961-6. PubMed ID: 16153831
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Novel prostaglandin D synthase inhibitors generated by fragment-based drug design.
    Hohwy M; Spadola L; Lundquist B; Hawtin P; Dahmén J; Groth-Clausen I; Nilsson E; Persdotter S; von Wachenfeldt K; Folmer RH; Edman K
    J Med Chem; 2008 Apr; 51(7):2178-86. PubMed ID: 18341273
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity.
    Grembecka J; Mucha A; Cierpicki T; Kafarski P
    J Med Chem; 2003 Jun; 46(13):2641-55. PubMed ID: 12801228
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13).
    Kim SH; Pudzianowski AT; Leavitt KJ; Barbosa J; McDonnell PA; Metzler WJ; Rankin BM; Liu R; Vaccaro W; Pitts W
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1101-6. PubMed ID: 15686921
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Quantitative evaluation of each catalytic subsite of cathepsin B for inhibitory activity based on inhibitory activity-binding mode relationship of epoxysuccinyl inhibitors by X-ray crystal structure analyses of complexes.
    Watanabe D; Yamamoto A; Tomoo K; Matsumoto K; Murata M; Kitamura K; Ishida T
    J Mol Biol; 2006 Oct; 362(5):979-93. PubMed ID: 16950396
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series.
    Stoll V; Stewart KD; Maring CJ; Muchmore S; Giranda V; Gu YG; Wang G; Chen Y; Sun M; Zhao C; Kennedy AL; Madigan DL; Xu Y; Saldivar A; Kati W; Laver G; Sowin T; Sham HL; Greer J; Kempf D
    Biochemistry; 2003 Jan; 42(3):718-27. PubMed ID: 12534284
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sultam hydroxamates as novel matrix metalloproteinase inhibitors.
    Cherney RJ; Mo R; Meyer DT; Hardman KD; Liu RQ; Covington MB; Qian M; Wasserman ZR; Christ DD; Trzaskos JM; Newton RC; Decicco CP
    J Med Chem; 2004 Jun; 47(12):2981-3. PubMed ID: 15163180
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pyrimidine-2,4,6-Triones: a new effective and selective class of matrix metalloproteinase inhibitors.
    Grams F; Brandstetter H; D'Alò S; Geppert D; Krell HW; Leinert H; Livi V; Menta E; Oliva A; Zimmermann G; Gram F; Brandstetter H; D'Alò S; Geppert D; Krell HW; Leinert H; Livi VMenta E; Oliva A; Zimmermann G
    Biol Chem; 2001 Aug; 382(8):1277-85. PubMed ID: 11592410
    [TBL] [Abstract][Full Text] [Related]  

  • 33. N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8.
    Campestre C; Agamennone M; Tortorella P; Preziuso S; Biasone A; Gavuzzo E; Pochetti G; Mazza F; Hiller O; Tschesche H; Consalvi V; Gallina C
    Bioorg Med Chem Lett; 2006 Jan; 16(1):20-4. PubMed ID: 16242329
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
    Rigden DJ; Botzki A; Nukui M; Mewbourne RB; Lamani E; Braun S; von Angerer E; Bernhardt G; Dove S; Buschauer A; Jedrzejas MJ
    Glycobiology; 2006 Aug; 16(8):757-65. PubMed ID: 16638841
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of potent and selective MMP-13 inhibitors.
    Wu J; Rush TS; Hotchandani R; Du X; Geck M; Collins E; Xu ZB; Skotnicki J; Levin JI; Lovering FE
    Bioorg Med Chem Lett; 2005 Sep; 15(18):4105-9. PubMed ID: 16005220
    [TBL] [Abstract][Full Text] [Related]  

  • 36. High-resolution solution structure of the inhibitor-free catalytic fragment of human fibroblast collagenase determined by multidimensional NMR.
    Moy FJ; Chanda PK; Cosmi S; Pisano MR; Urbano C; Wilhelm J; Powers R
    Biochemistry; 1998 Feb; 37(6):1495-504. PubMed ID: 9484219
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Matrix metalloproteinases in mild and severe temporomandibular joint internal derangement synovial fluid.
    Srinivas R; Sorsa T; Tjäderhane L; Niemi E; Raustia A; Pernu H; Teronen O; Salo T
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2001 May; 91(5):517-25. PubMed ID: 11346728
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Extra binding region induced by non-zinc chelating inhibitors into the S1' subsite of matrix metalloproteinase 8 (MMP-8).
    Pochetti G; Montanari R; Gege C; Chevrier C; Taveras AG; Mazza F
    J Med Chem; 2009 Feb; 52(4):1040-9. PubMed ID: 19173605
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors.
    Cheng XC; Wang Q; Fang H; Tang W; Xu WF
    Eur J Med Chem; 2008 Oct; 43(10):2130-9. PubMed ID: 18362041
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Fragment-based drug discovery.
    Erlanson DA; McDowell RS; O'Brien T
    J Med Chem; 2004 Jul; 47(14):3463-82. PubMed ID: 15214773
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.