BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 9464795)

  • 21. Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches.
    Tumas-Brundage K; Vora KA; Giusti AM; Manser T
    Semin Immunol; 1996 Jun; 8(3):141-50. PubMed ID: 8738913
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Indirect and direct evidence for DNA double-strand breaks in hypermutating immunoglobulin genes.
    Jacobs H; Rajewsky K; Fukita Y; Bross L
    Philos Trans R Soc Lond B Biol Sci; 2001 Jan; 356(1405):119-25. PubMed ID: 11205324
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A reporter gene to analyse the hypermutation of immunoglobulin genes.
    Chui YL; Lozano F; Jarvis JM; Pannell R; Milstein C
    J Mol Biol; 1995 Jun; 249(3):555-63. PubMed ID: 7783211
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.
    Yélamos J; Klix N; Goyenechea B; Lozano F; Chui YL; González Fernández A; Pannell R; Neuberger MS; Milstein C
    Nature; 1995 Jul; 376(6537):225-9. PubMed ID: 7617031
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Somatic hypermutation of an artificial test substrate within an Ig kappa transgene.
    Klotz EL; Hackett J; Storb U
    J Immunol; 1998 Jul; 161(2):782-90. PubMed ID: 9670955
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.
    Goyenechea B; Klix N; Yélamos J; Williams GT; Riddell A; Neuberger MS; Milstein C
    EMBO J; 1997 Jul; 16(13):3987-94. PubMed ID: 9233808
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Immunoglobulin transgenes as targets for somatic hypermutation.
    Storb U; Peters A; Klotz E; Kim N; Shen HM; Hackett J; Rogerson B; O'Brien R; Martin TE
    Int J Dev Biol; 1998; 42(7):977-82. PubMed ID: 9853828
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.
    Lebecque SG; Gearhart PJ
    J Exp Med; 1990 Dec; 172(6):1717-27. PubMed ID: 2258702
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Analysis of the effect of a strain-specific alteration in the upstream octamer region on transcription of a mouse V kappa Ser light chain gene.
    Goldrick MM; Gottlieb PD
    J Immunol; 1988 Jan; 140(2):646-53. PubMed ID: 2447185
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Non-random features of the repertoire expressed by the members of one V kappa gene family and of the V-J recombination.
    Milstein C; Even J; Jarvis JM; Gonzalez-Fernandez A; Gherardi E
    Eur J Immunol; 1992 Jun; 22(6):1627-34. PubMed ID: 1601044
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Multiple sequences from downstream of the J kappa cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain.
    Klix N; Jolly CJ; Davies SL; Brüggemann M; Williams GT; Neuberger MS
    Eur J Immunol; 1998 Jan; 28(1):317-26. PubMed ID: 9485211
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rearrangement of only one human IGHV gene is sufficient to generate a wide repertoire of antigen specific antibody responses in transgenic mice.
    Suárez E; Magadán S; Sanjuán I; Valladares M; Molina A; Gambón F; Díaz-Espada F; González-Fernández A
    Mol Immunol; 2006 Apr; 43(11):1827-35. PubMed ID: 16343622
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Influence of a V kappa 8 L chain transgene on endogenous rearrangements and the immune response to the HA(Sb) determinant on influenza virus.
    Carmack CE; Camper SA; Mackle JJ; Gerhard WU; Weigert MG
    J Immunol; 1991 Sep; 147(6):2024-33. PubMed ID: 1909739
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Defining the nucleic acid substrate for somatic hypermutation.
    Steele EJ; Rothenfluh HS; Both GW
    Immunol Cell Biol; 1992 Apr; 70 ( Pt 2)():129-44. PubMed ID: 1398773
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes.
    Umar A; Schweitzer PA; Levy NS; Gearhart JD; Gearhart PJ
    Proc Natl Acad Sci U S A; 1991 Jun; 88(11):4902-6. PubMed ID: 1905016
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.
    Sharpe MJ; Milstein C; Jarvis JM; Neuberger MS
    EMBO J; 1991 Aug; 10(8):2139-45. PubMed ID: 1905999
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region.
    Betz AG; Milstein C; González-Fernández A; Pannell R; Larson T; Neuberger MS
    Cell; 1994 Apr; 77(2):239-48. PubMed ID: 8168132
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Promoter-associated displacement of hypermutations.
    Wu P; Claflin L
    Int Immunol; 1998 Aug; 10(8):1131-8. PubMed ID: 9723699
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.
    Rogerson B; Hackett J; Peters A; Haasch D; Storb U
    EMBO J; 1991 Dec; 10(13):4331-41. PubMed ID: 1756738
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism.
    Winter DB; Gearhart PJ
    Immunol Rev; 1998 Apr; 162():89-96. PubMed ID: 9602355
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.