BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

679 related articles for article (PubMed ID: 9467563)

  • 1. Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma.
    Tonacchera M; Chiovato L; Pinchera A; Agretti P; Fiore E; Cetani F; Rocchi R; Viacava P; Miccoli P; Vitti P
    J Clin Endocrinol Metab; 1998 Feb; 83(2):492-8. PubMed ID: 9467563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter.
    Tonacchera M; Agretti P; Chiovato L; Rosellini V; Ceccarini G; Perri A; Viacava P; Naccarato AG; Miccoli P; Pinchera A; Vitti P
    J Clin Endocrinol Metab; 2000 Jun; 85(6):2270-4. PubMed ID: 10852462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutively activating TSH receptor mutations as the cause of toxic thyroid adenoma, multinodular toxic goiter and autosomal dominant non autoimmune hyperthyroidism.
    Paschke R
    Exp Clin Endocrinol Diabetes; 1996; 104 Suppl 4():129-32. PubMed ID: 8981020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter.
    Tonacchera M; Vitti P; Agretti P; Giulianetti B; Mazzi B; Cavaliere R; Ceccarini G; Fiore E; Viacava P; Naccarato A; Pinchera A; Chiovato L
    Thyroid; 1998 Jul; 8(7):559-64. PubMed ID: 9709907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functioning and nonfunctioning thyroid adenomas involve different molecular pathogenetic mechanisms.
    Tonacchera M; Vitti P; Agretti P; Ceccarini G; Perri A; Cavaliere R; Mazzi B; Naccarato AG; Viacava P; Miccoli P; Pinchera A; Chiovato L
    J Clin Endocrinol Metab; 1999 Nov; 84(11):4155-8. PubMed ID: 10566665
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Non-hyperfunctioning nodules from multinodular goiters: a minor role in pathogenesis for somatic activating mutations in the TSH-receptor and Gsalpha subunit genes.
    Derrien C; Sonnet E; Gicquel I; Le Gall JY; Poirier JY; David V; Maugendre D
    J Endocrinol Invest; 2001 May; 24(5):321-5. PubMed ID: 11407651
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Mutations in the thyrotropin receptor gene in the pathogenesis of toxic thyroid adenomas, toxic goiter nodules and autosomal dominant hyperthyroidism].
    Derwahl M
    Z Arztl Fortbild Qualitatssich; 1999 Apr; 93 Suppl 1():25-8. PubMed ID: 10355046
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Non-autoimmune hyperthyroidism and hyperfunctioning thyroid adenomas caused by activating mutation of the thyrotropin receptor].
    Kosugi S
    Nihon Rinsho; 2002 Feb; 60(2):291-6. PubMed ID: 11857916
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rarity of oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in Japan.
    Takeshita A; Nagayama Y; Yokoyama N; Ishikawa N; Ito K; Yamashita T; Obara T; Murakami Y; Kuma K; Takamatsu J
    J Clin Endocrinol Metab; 1995 Sep; 80(9):2607-11. PubMed ID: 7673402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pathogenesis of toxic thyroid adenomas and nodules: relevance of activating mutations in the TSH-receptor and Gs-alpha gene, the possible role of iodine deficiency and secondary and TSH-independent molecular mechanisms.
    Derwahl M; Manole D; Sobke A; Broecker M
    Exp Clin Endocrinol Diabetes; 1998; 106 Suppl 4():S6-9. PubMed ID: 9867188
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thyrotropin receptor mutations in hyperfunctioning thyroid adenomas from Brazil.
    Nogueira CR; Kopp P; Arseven OK; Santos CL; Jameson JL; Medeiros-Neto G
    Thyroid; 1999 Nov; 9(11):1063-8. PubMed ID: 10595453
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
    Parma J; Van Sande J; Swillens S; Tonacchera M; Dumont J; Vassart G
    Mol Endocrinol; 1995 Jun; 9(6):725-33. PubMed ID: 8592518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Two novel mutations in the sixth transmembrane segment of the thyrotropin receptor gene causing hyperfunctioning thyroid nodules.
    Gozu H; Avsar M; Bircan R; Claus M; Sahin S; Sezgin O; Deyneli O; Paschke R; Cirakoglu B; Akalin S
    Thyroid; 2005 Apr; 15(4):389-97. PubMed ID: 15876166
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas.
    Parma J; Duprez L; Van Sande J; Hermans J; Rocmans P; Van Vliet G; Costagliola S; Rodien P; Dumont JE; Vassart G
    J Clin Endocrinol Metab; 1997 Aug; 82(8):2695-701. PubMed ID: 9253356
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autonomously functioning thyroid nodules in a former iodine-deficient area commonly harbor gain-of-function mutations in the thyrotropin signaling pathway.
    Georgopoulos NA; Sykiotis GP; Sgourou A; Papachatzopoulou A; Markou KB; Kyriazopoulou V; Papavassiliou AG; Vagenakis AG
    Eur J Endocrinol; 2003 Oct; 149(4):287-92. PubMed ID: 14514342
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular aspects of the pathogenesis of nodular goiters, thyroid nodules and adenomas.
    Derwahl M
    Exp Clin Endocrinol Diabetes; 1996; 104 Suppl 4():32-5. PubMed ID: 8980997
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hyperfunctioning thyroid adenoma and activating mutations in the TSH receptor gene.
    Polak M
    Arch Med Res; 1999; 30(6):510-3. PubMed ID: 10714365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
    Paschke R; Tonacchera M; Van Sande J; Parma J; Vassart G
    J Clin Endocrinol Metab; 1994 Dec; 79(6):1785-9. PubMed ID: 7989485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of constitutively activating somatic thyrotropin receptor mutations in a subset of toxic multinodular goiters.
    Holzapfel HP; Führer D; Wonerow P; Weinland G; Scherbaum WA; Paschke R
    J Clin Endocrinol Metab; 1997 Dec; 82(12):4229-33. PubMed ID: 9398745
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of association of nonautoimmune hyperfunctioning thyroid disorders and a germline polymorphism of codon 727 of the human thyrotropin receptor in a European Caucasian population.
    Mühlberg T; Herrmann K; Joba W; Kirchberger M; Heberling HJ; Heufelder AE
    J Clin Endocrinol Metab; 2000 Aug; 85(8):2640-3. PubMed ID: 10946859
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.