BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

349 related articles for article (PubMed ID: 9472784)

  • 1. A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis.
    Knowles MR; Noone PG; Hohneker K; Johnson LG; Boucher RC; Efthimiou J; Crawford C; Brown R; Schwartzbach C; Pearlman R
    Hum Gene Ther; 1998 Jan; 9(2):249-69. PubMed ID: 9472784
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution.
    Konstan MW; Davis PB; Wagener JS; Hilliard KA; Stern RC; Milgram LJ; Kowalczyk TH; Hyatt SL; Fink TL; Gedeon CR; Oette SM; Payne JM; Muhammad O; Ziady AG; Moen RC; Cooper MJ
    Hum Gene Ther; 2004 Dec; 15(12):1255-69. PubMed ID: 15684701
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis.
    Knowles MR; Hohneker KW; Zhou Z; Olsen JC; Noah TL; Hu PC; Leigh MW; Engelhardt JF; Edwards LJ; Jones KR
    N Engl J Med; 1995 Sep; 333(13):823-31. PubMed ID: 7544439
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis.
    Noone PG; Hohneker KW; Zhou Z; Johnson LG; Foy C; Gipson C; Jones K; Noah TL; Leigh MW; Schwartzbach C; Efthimiou J; Pearlman R; Boucher RC; Knowles MR
    Mol Ther; 2000 Jan; 1(1):105-14. PubMed ID: 10933918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis.
    Gill DR; Southern KW; Mofford KA; Seddon T; Huang L; Sorgi F; Thomson A; MacVinish LJ; Ratcliff R; Bilton D; Lane DJ; Littlewood JM; Webb AK; Middleton PG; Colledge WH; Cuthbert AW; Evans MJ; Higgins CF; Hyde SC
    Gene Ther; 1997 Mar; 4(3):199-209. PubMed ID: 9135733
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.
    Porteous DJ; Dorin JR; McLachlan G; Davidson-Smith H; Davidson H; Stevenson BJ; Carothers AD; Wallace WA; Moralee S; Hoenes C; Kallmeyer G; Michaelis U; Naujoks K; Ho LP; Samways JM; Imrie M; Greening AP; Innes JA
    Gene Ther; 1997 Mar; 4(3):210-8. PubMed ID: 9135734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial.
    Alton EW; Stern M; Farley R; Jaffe A; Chadwick SL; Phillips J; Davies J; Smith SN; Browning J; Davies MG; Hodson ME; Durham SR; Li D; Jeffery PK; Scallan M; Balfour R; Eastman SJ; Cheng SH; Smith AE; Meeker D; Geddes DM
    Lancet; 1999 Mar; 353(9157):947-54. PubMed ID: 10459902
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis.
    Hyde SC; Southern KW; Gileadi U; Fitzjohn EM; Mofford KA; Waddell BE; Gooi HC; Goddard CA; Hannavy K; Smyth SE; Egan JJ; Sorgi FL; Huang L; Cuthbert AW; Evans MJ; Colledge WH; Higgins CF; Webb AK; Gill DR
    Gene Ther; 2000 Jul; 7(13):1156-65. PubMed ID: 10918483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Aerosol administration of a replication defective recombinant adenovirus expressing normal human cDNA-CFTR in the respiratory tractus in patients with cystic fibrosis].
    Bellon G; Calmard L; Thouvenot D; Levrey H; Jagneaux V; Poitevin F; Malcus C; Accart N; Séné C; Layani MP; Aymard M; Bienvenu J; Courtney M; Döring G; Gilly B; Gilly R; Lamy D; Morel Y; Paulin C; Perraud F; Rodillon L; So S; Touraine F; Schatz C; Pavirani A
    C R Seances Soc Biol Fil; 1996; 190(1):109-42. PubMed ID: 8881273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo nasal potential difference: techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis.
    Knowles MR; Paradiso AM; Boucher RC
    Hum Gene Ther; 1995 Apr; 6(4):445-55. PubMed ID: 7542031
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.
    Wagner JA; Messner AH; Moran ML; Daifuku R; Kouyama K; Desch JK; Manley S; Norbash AM; Conrad CK; Friborg S; Reynolds T; Guggino WB; Moss RB; Carter BJ; Wine JJ; Flotte TR; Gardner P
    Laryngoscope; 1999 Feb; 109(2 Pt 1):266-74. PubMed ID: 10890777
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.
    Zabner J; Cheng SH; Meeker D; Launspach J; Balfour R; Perricone MA; Morris JE; Marshall J; Fasbender A; Smith AE; Welsh MJ
    J Clin Invest; 1997 Sep; 100(6):1529-37. PubMed ID: 9294121
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector.
    Hay JG; McElvaney NG; Herena J; Crystal RG
    Hum Gene Ther; 1995 Nov; 6(11):1487-96. PubMed ID: 8573621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications.
    Joseph PM; O'Sullivan BP; Lapey A; Dorkin H; Oren J; Balfour R; Perricone MA; Rosenberg M; Wadsworth SC; Smith AE; St George JA; Meeker DP
    Hum Gene Ther; 2001 Jul; 12(11):1369-82. PubMed ID: 11485629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased contact time improves adenovirus-mediated CFTR gene transfer to nasal epithelium of CF mice.
    Jiang C; Akita GY; Colledge WH; Ratcliff RA; Evans MJ; Hehir KM; St George JA; Wadsworth SC; Cheng SH
    Hum Gene Ther; 1997 Apr; 8(6):671-80. PubMed ID: 9113507
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations.
    Wilschanski M; Yahav Y; Yaacov Y; Blau H; Bentur L; Rivlin J; Aviram M; Bdolah-Abram T; Bebok Z; Shushi L; Kerem B; Kerem E
    N Engl J Med; 2003 Oct; 349(15):1433-41. PubMed ID: 14534336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Laboratory and clinical studies in support of cystic fibrosis gene therapy using pCMV-CFTR-DOTAP.
    McLachlan G; Ho LP; Davidson-Smith H; Samways J; Davidson H; Stevenson BJ; Carothers AD; Alton EW; Middleton PG; Smith SN; Kallmeyer G; Michaelis U; Seeber S; Naujoks K; Greening AP; Innes JA; Dorin JR; Porteous DJ
    Gene Ther; 1996 Dec; 3(12):1113-23. PubMed ID: 8986438
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor.
    Ziady AG; Kelley TJ; Milliken E; Ferkol T; Davis PB
    Mol Ther; 2002 Apr; 5(4):413-9. PubMed ID: 11945068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Vector-specific complementation profiles of two independent primary defects in cystic fibrosis airways.
    Zhang Y; Jiang Q; Dudus L; Yankaskas JR; Engelhardt JF
    Hum Gene Ther; 1998 Mar; 9(5):635-48. PubMed ID: 9551612
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies.
    Wagner JA; Nepomuceno IB; Messner AH; Moran ML; Batson EP; Dimiceli S; Brown BW; Desch JK; Norbash AM; Conrad CK; Guggino WB; Flotte TR; Wine JJ; Carter BJ; Reynolds TC; Moss RB; Gardner P
    Hum Gene Ther; 2002 Jul; 13(11):1349-59. PubMed ID: 12162817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.