137 related articles for article (PubMed ID: 9477228)
1. Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.
Josephy PD; Evans DH; Parikh A; Guengerich FP
Chem Res Toxicol; 1998 Jan; 11(1):70-4. PubMed ID: 9477228
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of Escherichia coli DJ4309 expressing human P450 1A2 in mutagenicity testing of complex food mixtures.
Constable A; Varga N; Josephy PD; Guy P; Turesky RJ
Mutat Res; 1999 Jun; 442(2):79-87. PubMed ID: 10393276
[TBL] [Abstract][Full Text] [Related]
3. Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines.
Josephy PD; Evans DH; Williamson V; Henry T; Guengerich FP
Mutat Res; 1999 Oct; 429(2):199-208. PubMed ID: 10526205
[TBL] [Abstract][Full Text] [Related]
4. Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocyclic amines.
Suzuki A; Kushida H; Iwata H; Watanabe M; Nohmi T; Fujita K; Gonzalez FJ; Kamataki T
Cancer Res; 1998 May; 58(9):1833-8. PubMed ID: 9581821
[TBL] [Abstract][Full Text] [Related]
5. Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.
Duarte MP; Palma BB; Laires A; Oliveira JS; Rueff J; Kranendonk M
Mutagenesis; 2005 May; 20(3):199-208. PubMed ID: 15843388
[TBL] [Abstract][Full Text] [Related]
6. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
[TBL] [Abstract][Full Text] [Related]
7. Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase.
Dong MS; Yamazaki H; Guo Z; Guengerich FP
Arch Biochem Biophys; 1996 Mar; 327(1):11-9. PubMed ID: 8615680
[TBL] [Abstract][Full Text] [Related]
8. Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system.
Oda Y
Mutat Res; 2004 Oct; 554(1-2):399-406. PubMed ID: 15450435
[TBL] [Abstract][Full Text] [Related]
9. Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase.
Aryal P; Yoshikawa K; Terashita T; Guengerich FP; Shimada T; Oda Y
Mutat Res; 1999 Jun; 442(2):113-20. PubMed ID: 10393280
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
Guengerich FP; Humphreys WG; Yun CH; Hammons GJ; Kadlubar FF; Seto Y; Okazaki O; Martin MV
Princess Takamatsu Symp; 1995; 23():78-84. PubMed ID: 8844798
[TBL] [Abstract][Full Text] [Related]
11. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
[TBL] [Abstract][Full Text] [Related]
12. Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties.
Parikh A; Josephy PD; Guengerich FP
Biochemistry; 1999 Apr; 38(17):5283-9. PubMed ID: 10220313
[TBL] [Abstract][Full Text] [Related]
13. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
[TBL] [Abstract][Full Text] [Related]
14. Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens.
Yamazaki Y; Fujita K; Nakayama K; Suzuki A; Nakamura K; Yamazaki H; Kamataki T
Mutat Res; 2004 Aug; 562(1-2):151-62. PubMed ID: 15279838
[TBL] [Abstract][Full Text] [Related]
15. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
Oda Y; Watanabe T; Terao Y; Nukaya H; Wakabayashi K
Mutat Res; 2008 Jun; 654(1):52-7. PubMed ID: 18562244
[TBL] [Abstract][Full Text] [Related]
16. Expression, purification, and characterization of a catalytically active human cytochrome P450 1A2:rat NADPH-cytochrome P450 reductase fusion protein.
Parikh A; Guengerich FP
Protein Expr Purif; 1997 Apr; 9(3):346-54. PubMed ID: 9126606
[TBL] [Abstract][Full Text] [Related]
17. Interactions among P450 enzymes when combined in reconstituted systems: formation of a 2B4-1A2 complex with a high affinity for NADPH-cytochrome P450 reductase.
Backes WL; Batie CJ; Cawley GF
Biochemistry; 1998 Sep; 37(37):12852-9. PubMed ID: 9737863
[TBL] [Abstract][Full Text] [Related]
18. Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.
Oda Y; Totsuka Y; Wakabayashi K; Guengerich FP; Shimada T
Mutagenesis; 2006 Nov; 21(6):411-6. PubMed ID: 17067997
[TBL] [Abstract][Full Text] [Related]
19. Exposure levels and cytochrome P450 1A2 activity, but not N-acetyltransferase, glutathione S-transferase (GST) M1 and T1, influence urinary mutagen excretion in smokers.
Pavanello S; Simioli P; Lupi S; Gregorio P; Clonfero E
Cancer Epidemiol Biomarkers Prev; 2002 Oct; 11(10 Pt 1):998-1003. PubMed ID: 12376499
[TBL] [Abstract][Full Text] [Related]
20. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]