These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 9477228)

  • 1. Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.
    Josephy PD; Evans DH; Parikh A; Guengerich FP
    Chem Res Toxicol; 1998 Jan; 11(1):70-4. PubMed ID: 9477228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of Escherichia coli DJ4309 expressing human P450 1A2 in mutagenicity testing of complex food mixtures.
    Constable A; Varga N; Josephy PD; Guy P; Turesky RJ
    Mutat Res; 1999 Jun; 442(2):79-87. PubMed ID: 10393276
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines.
    Josephy PD; Evans DH; Williamson V; Henry T; Guengerich FP
    Mutat Res; 1999 Oct; 429(2):199-208. PubMed ID: 10526205
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocyclic amines.
    Suzuki A; Kushida H; Iwata H; Watanabe M; Nohmi T; Fujita K; Gonzalez FJ; Kamataki T
    Cancer Res; 1998 May; 58(9):1833-8. PubMed ID: 9581821
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.
    Duarte MP; Palma BB; Laires A; Oliveira JS; Rueff J; Kranendonk M
    Mutagenesis; 2005 May; 20(3):199-208. PubMed ID: 15843388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.
    Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
    Environ Mol Mutagen; 2000; 36(2):121-6. PubMed ID: 11013410
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase.
    Dong MS; Yamazaki H; Guo Z; Guengerich FP
    Arch Biochem Biophys; 1996 Mar; 327(1):11-9. PubMed ID: 8615680
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system.
    Oda Y
    Mutat Res; 2004 Oct; 554(1-2):399-406. PubMed ID: 15450435
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase.
    Aryal P; Yoshikawa K; Terashita T; Guengerich FP; Shimada T; Oda Y
    Mutat Res; 1999 Jun; 442(2):113-20. PubMed ID: 10393280
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanisms of cytochrome P450 1A2-mediated formation of N-hydroxy arylamines and heterocyclic amines and their reaction with guanyl residues.
    Guengerich FP; Humphreys WG; Yun CH; Hammons GJ; Kadlubar FF; Seto Y; Okazaki O; Martin MV
    Princess Takamatsu Symp; 1995; 23():78-84. PubMed ID: 8844798
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
    Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
    Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties.
    Parikh A; Josephy PD; Guengerich FP
    Biochemistry; 1999 Apr; 38(17):5283-9. PubMed ID: 10220313
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
    Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens.
    Yamazaki Y; Fujita K; Nakayama K; Suzuki A; Nakamura K; Yamazaki H; Kamataki T
    Mutat Res; 2004 Aug; 562(1-2):151-62. PubMed ID: 15279838
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
    Oda Y; Watanabe T; Terao Y; Nukaya H; Wakabayashi K
    Mutat Res; 2008 Jun; 654(1):52-7. PubMed ID: 18562244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression, purification, and characterization of a catalytically active human cytochrome P450 1A2:rat NADPH-cytochrome P450 reductase fusion protein.
    Parikh A; Guengerich FP
    Protein Expr Purif; 1997 Apr; 9(3):346-54. PubMed ID: 9126606
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interactions among P450 enzymes when combined in reconstituted systems: formation of a 2B4-1A2 complex with a high affinity for NADPH-cytochrome P450 reductase.
    Backes WL; Batie CJ; Cawley GF
    Biochemistry; 1998 Sep; 37(37):12852-9. PubMed ID: 9737863
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.
    Oda Y; Totsuka Y; Wakabayashi K; Guengerich FP; Shimada T
    Mutagenesis; 2006 Nov; 21(6):411-6. PubMed ID: 17067997
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exposure levels and cytochrome P450 1A2 activity, but not N-acetyltransferase, glutathione S-transferase (GST) M1 and T1, influence urinary mutagen excretion in smokers.
    Pavanello S; Simioli P; Lupi S; Gregorio P; Clonfero E
    Cancer Epidemiol Biomarkers Prev; 2002 Oct; 11(10 Pt 1):998-1003. PubMed ID: 12376499
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stable expression and coexpression of human cytochrome P450 oxidoreductase and cytochrome P450 1A2 in V79 Chinese hamster cells: sensitivity to quinones and biotransformation of 7-alkoxyresorufins and triazines.
    Schmalix WA; Lang D; Schneider A; Bocker R; Greim H; Doehmer J
    Drug Metab Dispos; 1996 Dec; 24(12):1314-9. PubMed ID: 8971136
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.