These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 9482899)

  • 1. Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.
    Zhou S; Buckhaults P; Zawel L; Bunz F; Riggins G; Dai JL; Kern SE; Kinzler KW; Vogelstein B
    Proc Natl Acad Sci U S A; 1998 Mar; 95(5):2412-6. PubMed ID: 9482899
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP; Roelen BA; ten Dijke P; van der Burg B; van den Eijnden-van Raaij AJ
    Oncogene; 1997 Apr; 14(16):1891-9. PubMed ID: 9150356
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.
    Liu F; Pouponnot C; Massagué J
    Genes Dev; 1997 Dec; 11(23):3157-67. PubMed ID: 9389648
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads.
    Candia AF; Watabe T; Hawley SH; Onichtchouk D; Zhang Y; Derynck R; Niehrs C; Cho KW
    Development; 1997 Nov; 124(22):4467-80. PubMed ID: 9409665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smad3 inhibits transforming growth factor-beta and activin signaling by competing with Smad4 for FAST-2 binding.
    Nagarajan RP; Liu J; Chen Y
    J Biol Chem; 1999 Oct; 274(44):31229-35. PubMed ID: 10531318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.
    Sirard C; Kim S; Mirtsos C; Tadich P; Hoodless PA; Itié A; Maxson R; Wrana JL; Mak TW
    J Biol Chem; 2000 Jan; 275(3):2063-70. PubMed ID: 10636910
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function.
    Zhang Y; Musci T; Derynck R
    Curr Biol; 1997 Apr; 7(4):270-6. PubMed ID: 9094310
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of human FAST-1, a TGF beta and activin signal transducer.
    Zhou S; Zawel L; Lengauer C; Kinzler KW; Vogelstein B
    Mol Cell; 1998 Jul; 2(1):121-7. PubMed ID: 9702198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis.
    Yeo CY; Chen X; Whitman M
    J Biol Chem; 1999 Sep; 274(37):26584-90. PubMed ID: 10473623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells.
    De Bosscher K; Hill CS; Nicolás FJ
    Biochem J; 2004 Apr; 379(Pt 1):209-16. PubMed ID: 14715079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes.
    Howell M; Itoh F; Pierreux CE; Valgeirsdottir S; Itoh S; ten Dijke P; Hill CS
    Dev Biol; 1999 Oct; 214(2):354-69. PubMed ID: 10525340
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif.
    Germain S; Howell M; Esslemont GM; Hill CS
    Genes Dev; 2000 Feb; 14(4):435-51. PubMed ID: 10691736
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.
    Lagna G; Hata A; Hemmati-Brivanlou A; Massagué J
    Nature; 1996 Oct; 383(6603):832-6. PubMed ID: 8893010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B; Fleming JB; Breslin T; Grau AM; Fojioka S; Abbruzzese JL; Evans DB; Ayers D; Wathen K; Wu T; Robertson KD; Chiao PJ
    Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2.
    Labbé E; Silvestri C; Hoodless PA; Wrana JL; Attisano L
    Mol Cell; 1998 Jul; 2(1):109-20. PubMed ID: 9702197
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
    Chiao PJ; Hunt KK; Grau AM; Abramian A; Fleming J; Zhang W; Breslin T; Abbruzzese JL; Evans DB
    Ann N Y Acad Sci; 1999 Jun; 880():31-7. PubMed ID: 10415848
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Restoration of transforming growth factor Beta signaling by functional expression of smad4 induces anoikis.
    Ramachandra M; Atencio I; Rahman A; Vaillancourt M; Zou A; Avanzini J; Wills K; Bookstein R; Shabram P
    Cancer Res; 2002 Nov; 62(21):6045-51. PubMed ID: 12414627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of specific gene mutations in the transforming growth factor-beta signal transduction pathway in human ovarian cancer.
    Wang D; Kanuma T; Mizunuma H; Takama F; Ibuki Y; Wake N; Mogi A; Shitara Y; Takenoshita S
    Cancer Res; 2000 Aug; 60(16):4507-12. PubMed ID: 10969799
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of functional domains within Smad4/DPC4.
    de Caestecker MP; Hemmati P; Larisch-Bloch S; Ajmera R; Roberts AB; Lechleider RJ
    J Biol Chem; 1997 May; 272(21):13690-6. PubMed ID: 9153220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear localization of Dpc4 (Madh4, Smad4) in colorectal carcinomas and relation to mismatch repair/transforming growth factor-beta receptor defects.
    Montgomery E; Goggins M; Zhou S; Argani P; Wilentz R; Kaushal M; Booker S; Romans K; Bhargava P; Hruban R; Kern S
    Am J Pathol; 2001 Feb; 158(2):537-42. PubMed ID: 11159190
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.