BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 9484221)

  • 1. Effects of mutations on the partitioning of DNA substrates between the polymerase and 3'-5' exonuclease sites of DNA polymerase I (Klenow fragment).
    Lam WC; Van der Schans EJ; Joyce CM; Millar DP
    Biochemistry; 1998 Feb; 37(6):1513-22. PubMed ID: 9484221
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recognition of sequence-directed DNA structure by the Klenow fragment of DNA polymerase I.
    Carver TE; Millar DP
    Biochemistry; 1998 Feb; 37(7):1898-904. PubMed ID: 9485315
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction of DNA polymerase I (Klenow fragment) with DNA substrates containing extrahelical bases: implications for proofreading of frameshift errors during DNA synthesis.
    Lam WC; Van der Schans EJ; Sowers LC; Millar DP
    Biochemistry; 1999 Mar; 38(9):2661-8. PubMed ID: 10052936
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exonuclease-polymerase active site partitioning of primer-template DNA strands and equilibrium Mg2+ binding properties of bacteriophage T4 DNA polymerase.
    Beechem JM; Otto MR; Bloom LB; Eritja R; Reha-Krantz LJ; Goodman MF
    Biochemistry; 1998 Jul; 37(28):10144-55. PubMed ID: 9665720
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch.
    Singh K; Modak MJ
    Biochemistry; 2005 Jun; 44(22):8101-10. PubMed ID: 15924429
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting.
    Lam WC; Thompson EH; Potapova O; Sun XC; Joyce CM; Millar DP
    Biochemistry; 2002 Mar; 41(12):3943-51. PubMed ID: 11900537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing DNA polymerase fidelity mechanisms using time-resolved fluorescence anisotropy.
    Bailey MF; Thompson EH; Millar DP
    Methods; 2001 Sep; 25(1):62-77. PubMed ID: 11558998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determinants of DNA mismatch recognition within the polymerase domain of the Klenow fragment.
    Thompson EH; Bailey MF; van der Schans EJ; Joyce CM; Millar DP
    Biochemistry; 2002 Jan; 41(3):713-22. PubMed ID: 11790092
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions.
    Wang J; Yu P; Lin TC; Konigsberg WH; Steitz TA
    Biochemistry; 1996 Jun; 35(25):8110-9. PubMed ID: 8679562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.
    Derbyshire V; Grindley ND; Joyce CM
    EMBO J; 1991 Jan; 10(1):17-24. PubMed ID: 1989882
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thermodynamic dissection of the polymerizing and editing modes of a DNA polymerase.
    Bailey MF; van der Schans EJ; Millar DP
    J Mol Biol; 2004 Feb; 336(3):673-93. PubMed ID: 15095980
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phage phi 29 DNA polymerase residues involved in the proper stabilisation of the primer-terminus at the 3'-5' exonuclease active site.
    de Vega M; Lázaro JM; Salas M
    J Mol Biol; 2000 Nov; 304(1):1-9. PubMed ID: 11071805
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase.
    Abdus Sattar AK; Lin TC; Jones C; Konigsberg WH
    Biochemistry; 1996 Dec; 35(51):16621-9. PubMed ID: 8987997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dimerization of the Klenow fragment of Escherichia coli DNA polymerase I is linked to its mode of DNA binding.
    Bailey MF; Van der Schans EJ; Millar DP
    Biochemistry; 2007 Jul; 46(27):8085-99. PubMed ID: 17567151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pre-steady-state kinetics of RB69 DNA polymerase and its exo domain mutants: effect of pH and thiophosphoryl linkages on 3'-5' exonuclease activity.
    Wang CX; Zakharova E; Li J; Joyce CM; Wang J; Konigsberg W
    Biochemistry; 2004 Apr; 43(13):3853-61. PubMed ID: 15049692
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A domain of the Klenow fragment of Escherichia coli DNA polymerase I has polymerase but no exonuclease activity.
    Freemont PS; Ollis DL; Steitz TA; Joyce CM
    Proteins; 1986 Sep; 1(1):66-73. PubMed ID: 3329725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of DNA minor groove interactions by exonuclease-deficient Klenow polymerase inhibits O6-methylguanine and abasic site translesion synthesis.
    Gestl EE; Eckert KA
    Biochemistry; 2005 May; 44(18):7059-68. PubMed ID: 15865450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stopped-flow fluorescence study of precatalytic primer strand base-unstacking transitions in the exonuclease cleft of bacteriophage T4 DNA polymerase.
    Otto MR; Bloom LB; Goodman MF; Beechem JM
    Biochemistry; 1998 Jul; 37(28):10156-63. PubMed ID: 9665721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
    Brautigam CA; Sun S; Piccirilli JA; Steitz TA
    Biochemistry; 1999 Jan; 38(2):696-704. PubMed ID: 9888810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I.
    Carver TE; Hochstrasser RA; Millar DP
    Proc Natl Acad Sci U S A; 1994 Oct; 91(22):10670-4. PubMed ID: 7938011
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.