127 related articles for article (PubMed ID: 9484493)
1. Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid.
Hopper AT; Witiak DT; Ziemniak J
J Med Chem; 1998 Feb; 41(4):420-7. PubMed ID: 9484493
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
Cusan C; Spalluto G; Prato M; Adams M; Bodensieck A; Bauer R; Tubaro A; Bernardi P; Da Ros T
Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents.
Selvam C; Jachak SM; Thilagavathi R; Chakraborti AK
Bioorg Med Chem Lett; 2005 Apr; 15(7):1793-7. PubMed ID: 15780608
[TBL] [Abstract][Full Text] [Related]
4. Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.
Hong SH; Avis I; Vos MD; Martínez A; Treston AM; Mulshine JL
Cancer Res; 1999 May; 59(9):2223-8. PubMed ID: 10232612
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
[TBL] [Abstract][Full Text] [Related]
6. In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives.
Shin SS; Byun Y; Lim KM; Choi JK; Lee KW; Moh JH; Kim JK; Jeong YS; Kim JY; Choi YH; Koh HJ; Park YH; Oh YI; Noh MS; Chung S
J Med Chem; 2004 Feb; 47(4):792-804. PubMed ID: 14761182
[TBL] [Abstract][Full Text] [Related]
7. Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
Chan CC; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Ford-Hutchinson AW; Forrest MJ; Gauthier JY; Gordon R; Gresser M; Guay J; Kargman S; Kennedy B; Leblanc Y; Leger S; Mancini J; O'Neill GP; Ouellet M; Patrick D; Percival MD; Perrier H; Prasit P; Rodger I
J Pharmacol Exp Ther; 1999 Aug; 290(2):551-60. PubMed ID: 10411562
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
Pontiki E; Hadjipavlou-Litina D; Litinas K; Nicolotti O; Carotti A
Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Apr; 13(7):2459-68. PubMed ID: 15755648
[TBL] [Abstract][Full Text] [Related]
11. Inhibitory effects of maesanin and analogs on arachidonic acid metabolizing enzymes.
Abourashed EA; Muhammad I; Resch M; Bauer R; el-Feraly FS; Hufford CD
Planta Med; 2001 Jun; 67(4):360-1. PubMed ID: 11458456
[TBL] [Abstract][Full Text] [Related]
12. Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
Gray PA; Warner TD; Vojnovic I; Del Soldato P; Parikh A; Scadding GK; Mitchell JA
Br J Pharmacol; 2002 Dec; 137(7):1031-8. PubMed ID: 12429575
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
Moreau A; Chen QH; Praveen Rao PN; Knaus EE
Bioorg Med Chem; 2006 Dec; 14(23):7716-27. PubMed ID: 16931030
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
16. Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal.
Di Nunno L; Vitale P; Scilimati A; Tacconelli S; Patrignani P
J Med Chem; 2004 Sep; 47(20):4881-90. PubMed ID: 15369392
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.
Yu G; Praveen Rao PN; Chowdhury MA; Abdellatif KR; Dong Y; Das D; Velázquez CA; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2010 Apr; 20(7):2168-73. PubMed ID: 20202839
[TBL] [Abstract][Full Text] [Related]
18. [Inhibition of the arachidonic acid cascade by aza-2-aryl-1,4-naphthoquinone derivatives].
Richwien A; Wurm G
Pharmazie; 2004 Dec; 59(12):906-12. PubMed ID: 15638076
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
