These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 9485401)

  • 1. Functional orientation of the acyltransferase domain in a module of the erythromycin polyketide synthase.
    Gokhale RS; Lau J; Cane DE; Khosla C
    Biochemistry; 1998 Feb; 37(8):2524-8. PubMed ID: 9485401
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase.
    Kao CM; Pieper R; Cane DE; Khosla C
    Biochemistry; 1996 Sep; 35(38):12363-8. PubMed ID: 8823171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
    Hans M; Hornung A; Dziarnowski A; Cane DE; Khosla C
    J Am Chem Soc; 2003 May; 125(18):5366-74. PubMed ID: 12720450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
    Lau J; Fu H; Cane DE; Khosla C
    Biochemistry; 1999 Feb; 38(5):1643-51. PubMed ID: 9931032
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
    Kumar P; Koppisch AT; Cane DE; Khosla C
    J Am Chem Soc; 2003 Nov; 125(47):14307-12. PubMed ID: 14624579
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase.
    Pieper R; Gokhale RS; Luo G; Cane DE; Khosla C
    Biochemistry; 1997 Feb; 36(7):1846-51. PubMed ID: 9048569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
    Liou GF; Lau J; Cane DE; Khosla C
    Biochemistry; 2003 Jan; 42(1):200-7. PubMed ID: 12515555
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The malonyl/acetyltransferase and beta-ketoacyl synthase domains of the animal fatty acid synthase can cooperate with the acyl carrier protein domain of either subunit.
    Joshi AK; Witkowski A; Smith S
    Biochemistry; 1998 Feb; 37(8):2515-23. PubMed ID: 9485400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY; Alekseyev VY; Chen AY; Tang Y; Cane DE; Khosla C
    Biochemistry; 2004 Nov; 43(44):13892-8. PubMed ID: 15518537
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 6-deoxyerythronolide B synthase 1 is specifically acylated by a diketide intermediate at the beta-ketoacyl-acyl carrier protein synthase domain of module 2.
    Tsukamoto N; Chuck JA; Luo G; Kao CM; Khosla C; Cane DE
    Biochemistry; 1996 Dec; 35(48):15244-8. PubMed ID: 8952473
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Origin of starter units for erythromycin biosynthesis.
    Weissman KJ; Bycroft M; Staunton J; Leadlay PF
    Biochemistry; 1998 Aug; 37(31):11012-7. PubMed ID: 9692995
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis.
    Jacobsen JR; Cane DE; Khosla C
    Biochemistry; 1998 Apr; 37(14):4928-34. PubMed ID: 9538011
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates.
    Pieper R; Ebert-Khosla S; Cane D; Khosla C
    Biochemistry; 1996 Feb; 35(7):2054-60. PubMed ID: 8652546
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases.
    Pieper R; Luo G; Cane DE; Khosla C
    Nature; 1995 Nov; 378(6554):263-6. PubMed ID: 7477343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.
    Reid R; Piagentini M; Rodriguez E; Ashley G; Viswanathan N; Carney J; Santi DV; Hutchinson CR; McDaniel R
    Biochemistry; 2003 Jan; 42(1):72-9. PubMed ID: 12515540
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of molecular recognition in the pikromycin polyketide synthase.
    Chen S; Xue Y; Sherman DH; Reynolds KA
    Chem Biol; 2000 Dec; 7(12):907-18. PubMed ID: 11137814
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer.
    Dreier J; Khosla C
    Biochemistry; 2000 Feb; 39(8):2088-95. PubMed ID: 10684659
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
    Ruan X; Pereda A; Stassi DL; Zeidner D; Summers RG; Jackson M; Shivakumar A; Kakavas S; Staver MJ; Donadio S; Katz L
    J Bacteriol; 1997 Oct; 179(20):6416-25. PubMed ID: 9335291
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
    Tang L; Yoon YJ; Choi CY; Hutchinson CR
    Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.