225 related articles for article (PubMed ID: 9485427)
1. Cleavage efficiency of the novel aspartic protease yapsin 1 (Yap3p) enhanced for substrates with arginine residues flanking the P1 site: correlation with electronegative active-site pockets predicted by molecular modeling.
Olsen V; Guruprasad K; Cawley NX; Chen HC; Blundell TL; Loh YP
Biochemistry; 1998 Mar; 37(9):2768-77. PubMed ID: 9485427
[TBL] [Abstract][Full Text] [Related]
2. Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis.
Le Bonniec BF; Myles T; Johnson T; Knight CG; Tapparelli C; Stone SR
Biochemistry; 1996 Jun; 35(22):7114-22. PubMed ID: 8679538
[TBL] [Abstract][Full Text] [Related]
3. Engineering the S1' subsite of trypsin: design of a protease which cleaves between dibasic residues.
Kurth T; Grahn S; Thormann M; Ullmann D; Hofmann HJ; Jakubke HD; Hedstrom L
Biochemistry; 1998 Aug; 37(33):11434-40. PubMed ID: 9708978
[TBL] [Abstract][Full Text] [Related]
4. IL-1-converting enzyme requires aspartic acid residues for processing of the IL-1 beta precursor at two distinct sites and does not cleave 31-kDa IL-1 alpha.
Howard AD; Kostura MJ; Thornberry N; Ding GJ; Limjuco G; Weidner J; Salley JP; Hogquist KA; Chaplin DD; Mumford RA
J Immunol; 1991 Nov; 147(9):2964-9. PubMed ID: 1919001
[TBL] [Abstract][Full Text] [Related]
5. Identification and characterization of Saccharomyces cerevisiae yapsin 3, a new member of the yapsin family of aspartic proteases encoded by the YPS3 gene.
Olsen V; Cawley NX; Brandt J; Egel-Mitani M; Loh YP
Biochem J; 1999 Apr; 339 ( Pt 2)(Pt 2):407-11. PubMed ID: 10191273
[TBL] [Abstract][Full Text] [Related]
6. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
Sauder JM; Arthur JW; Dunbrack RL
J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
[TBL] [Abstract][Full Text] [Related]
7. Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Slon-Usakiewicz JJ; Sivaraman J; Li Y; Cygler M; Konishi Y
Biochemistry; 2000 Mar; 39(9):2384-91. PubMed ID: 10694407
[TBL] [Abstract][Full Text] [Related]
8. X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus.
Newman M; Watson F; Roychowdhury P; Jones H; Badasso M; Cleasby A; Wood SP; Tickle IJ; Blundell TL
J Mol Biol; 1993 Mar; 230(1):260-83. PubMed ID: 8450540
[TBL] [Abstract][Full Text] [Related]
9. The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity.
Kiss AL; Hornung B; Rádi K; Gengeliczki Z; Sztáray B; Juhász T; Szeltner Z; Harmat V; Polgár L
J Mol Biol; 2007 Apr; 368(2):509-20. PubMed ID: 17350041
[TBL] [Abstract][Full Text] [Related]
10. Kinetic and modeling studies of S3-S3' subsites of HIV proteinases.
Tözsér J; Weber IT; Gustchina A; Bláha I; Copeland TD; Louis JM; Oroszlan S
Biochemistry; 1992 May; 31(20):4793-800. PubMed ID: 1591240
[TBL] [Abstract][Full Text] [Related]
11. Understanding the P1' specificity of the matrix metalloproteinases: effect of S1' pocket mutations in matrilysin and stromelysin-1.
Welch AR; Holman CM; Huber M; Brenner MC; Browner MF; Van Wart HE
Biochemistry; 1996 Aug; 35(31):10103-9. PubMed ID: 8756473
[TBL] [Abstract][Full Text] [Related]
12. Specificity and kinetic studies on the cleavage of various prohormone mono- and paired-basic residue sites by yeast aspartic protease 3.
Cawley NX; Chen HC; Beinfeld MC; Loh YP
J Biol Chem; 1996 Feb; 271(8):4168-76. PubMed ID: 8626758
[TBL] [Abstract][Full Text] [Related]
13. NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
Song J; Laskowski M; Qasim MA; Markley JL
Biochemistry; 2003 Mar; 42(10):2847-56. PubMed ID: 12627950
[TBL] [Abstract][Full Text] [Related]
14. Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure.
Lang R; Kocourek A; Braun M; Tschesche H; Huber R; Bode W; Maskos K
J Mol Biol; 2001 Sep; 312(4):731-42. PubMed ID: 11575928
[TBL] [Abstract][Full Text] [Related]
15. Comparative molecular model building of two serine proteinases from cytotoxic T lymphocytes.
Murphy ME; Moult J; Bleackley RC; Gershenfeld H; Weissman IL; James MN
Proteins; 1988; 4(3):190-204. PubMed ID: 3237717
[TBL] [Abstract][Full Text] [Related]
16. Subsite specificity studies on the unusual cysteine protease clostripain: charged residues in the P3 position indicate a narrow subsite region.
Bordusa F; Ullmann D; Jakubke HD
Biol Chem; 1997 Oct; 378(10):1193-8. PubMed ID: 9372191
[TBL] [Abstract][Full Text] [Related]
17. An SRLLR motif downstream of the scissile bond enhances enterokinase cleavage efficiency.
Liew OW; Jenny Chong PC; Lim YZ; Ang CX; Amy Lau YC; Yandle TG; Brennan SO
Biochimie; 2007 Jan; 89(1):21-9. PubMed ID: 17097793
[TBL] [Abstract][Full Text] [Related]
18. Subsite specificity (S3, S2, S1', S2' and S3') of oligopeptidase B from Trypanosoma cruzi and Trypanosoma brucei using fluorescent quenched peptides: comparative study and identification of specific carboxypeptidase activity.
Hemerly JP; Oliveira V; Del Nery E; Morty RE; Andrews NW; Juliano MA; Juliano L
Biochem J; 2003 Aug; 373(Pt 3):933-9. PubMed ID: 12737623
[TBL] [Abstract][Full Text] [Related]
19. Secondary substrate binding in aspartic proteinases: contributions of subsites S3 and S'2 to kcat.
Balbaa M; Cunningham A; Hofmann T
Arch Biochem Biophys; 1993 Nov; 306(2):297-303. PubMed ID: 8215428
[TBL] [Abstract][Full Text] [Related]
20. Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL
Cesar Ramos de Jesus H; Solis N; Machado Y; Pablos I; Bell PA; Kappelhoff R; Grin PM; Sorgi CA; Butler GS; Overall CM
J Virol; 2024 Jun; 98(6):e0004924. PubMed ID: 38742901
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
