1190 related articles for article (PubMed ID: 9486655)
1. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.
Grignani F; De Matteis S; Nervi C; Tomassoni L; Gelmetti V; Cioce M; Fanelli M; Ruthardt M; Ferrara FF; Zamir I; Seiser C; Grignani F; Lazar MA; Minucci S; Pelicci PG
Nature; 1998 Feb; 391(6669):815-8. PubMed ID: 9486655
[TBL] [Abstract][Full Text] [Related]
2. Role of the histone deacetylase complex in acute promyelocytic leukaemia.
Lin RJ; Nagy L; Inoue S; Shao W; Miller WH; Evans RM
Nature; 1998 Feb; 391(6669):811-4. PubMed ID: 9486654
[TBL] [Abstract][Full Text] [Related]
3. Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.
He LZ; Guidez F; Tribioli C; Peruzzi D; Ruthardt M; Zelent A; Pandolfi PP
Nat Genet; 1998 Feb; 18(2):126-35. PubMed ID: 9462740
[TBL] [Abstract][Full Text] [Related]
4. Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
Ruthardt M; Testa U; Nervi C; Ferrucci PF; Grignani F; Puccetti E; Grignani F; Peschle C; Pelicci PG
Mol Cell Biol; 1997 Aug; 17(8):4859-69. PubMed ID: 9234742
[TBL] [Abstract][Full Text] [Related]
5. Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.
Guidez F; Ivins S; Zhu J; Söderström M; Waxman S; Zelent A
Blood; 1998 Apr; 91(8):2634-42. PubMed ID: 9531570
[TBL] [Abstract][Full Text] [Related]
6. Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.
Puccetti E; Sennewald B; Fosca-Ferrara F; Boehrer S; Bianchini A; Hoelzer D; Ottmann OG; Nervi C; Ruthardt M
Hematol J; 2001; 2(6):385-92. PubMed ID: 11920278
[TBL] [Abstract][Full Text] [Related]
7. Fusion protein of retinoic acid receptor alpha with promyelocytic leukemia protein or promyelocytic leukemia zinc finger protein recruits N-CoR-TBLR1 corepressor complex to repress transcription in vivo.
Tomita A; Buchholz DR; Obata K; Shi YB
J Biol Chem; 2003 Aug; 278(33):30788-95. PubMed ID: 12794076
[TBL] [Abstract][Full Text] [Related]
8. In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.
Matsushita H; Scaglioni PP; Bhaumik M; Rego EM; Cai LF; Majid SM; Miyachi H; Kakizuka A; Miller WH; Pandolfi PP
J Exp Med; 2006 Apr; 203(4):821-8. PubMed ID: 16549595
[TBL] [Abstract][Full Text] [Related]
9. HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF.
Chauchereau A; Mathieu M; de Saintignon J; Ferreira R; Pritchard LL; Mishal Z; Dejean A; Harel-Bellan A
Oncogene; 2004 Nov; 23(54):8777-84. PubMed ID: 15467736
[TBL] [Abstract][Full Text] [Related]
10. Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo.
Atsumi A; Tomita A; Kiyoi H; Naoe T
Biochem Biophys Res Commun; 2006 Jul; 345(4):1471-80. PubMed ID: 16730330
[TBL] [Abstract][Full Text] [Related]
11. Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient.
Koken MH; Daniel MT; Gianni M; Zelent A; Licht J; Buzyn A; Minard P; Degos L; Varet B; de Thé H
Oncogene; 1999 Jan; 18(4):1113-8. PubMed ID: 10023688
[TBL] [Abstract][Full Text] [Related]
12. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia.
Hong SH; David G; Wong CW; Dejean A; Privalsky ML
Proc Natl Acad Sci U S A; 1997 Aug; 94(17):9028-33. PubMed ID: 9256429
[TBL] [Abstract][Full Text] [Related]
13. Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha.
Cheng GX; Zhu XH; Men XQ; Wang L; Huang QH; Jin XL; Xiong SM; Zhu J; Guo WM; Chen JQ; Xu SF; So E; Chan LC; Waxman S; Zelent A; Chen GQ; Dong S; Liu JX; Chen SJ
Proc Natl Acad Sci U S A; 1999 May; 96(11):6318-23. PubMed ID: 10339585
[TBL] [Abstract][Full Text] [Related]
14. Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo.
Zhou DC; Kim SH; Ding W; Schultz C; Warrell RP; Gallagher RE
Blood; 2002 Feb; 99(4):1356-63. PubMed ID: 11830487
[TBL] [Abstract][Full Text] [Related]
15. Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein.
Dong S; Zhu J; Reid A; Strutt P; Guidez F; Zhong HJ; Wang ZY; Licht J; Waxman S; Chomienne C; Chen Z; Zelent A; Chen SJ
Proc Natl Acad Sci U S A; 1996 Apr; 93(8):3624-9. PubMed ID: 8622986
[TBL] [Abstract][Full Text] [Related]
16. A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins.
Zhong S; Delva L; Rachez C; Cenciarelli C; Gandini D; Zhang H; Kalantry S; Freedman LP; Pandolfi PP
Nat Genet; 1999 Nov; 23(3):287-95. PubMed ID: 10610177
[TBL] [Abstract][Full Text] [Related]
17. AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
Puccetti E; Obradovic D; Beissert T; Bianchini A; Washburn B; Chiaradonna F; Boehrer S; Hoelzer D; Ottmann OG; Pelicci PG; Nervi C; Ruthardt M
Cancer Res; 2002 Dec; 62(23):7050-8. PubMed ID: 12460926
[TBL] [Abstract][Full Text] [Related]
18. PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.
Sternsdorf T; Puccetti E; Jensen K; Hoelzer D; Will H; Ottmann OG; Ruthardt M
Mol Cell Biol; 1999 Jul; 19(7):5170-8. PubMed ID: 10373566
[TBL] [Abstract][Full Text] [Related]
19. Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia.
He LZ; Tolentino T; Grayson P; Zhong S; Warrell RP; Rifkind RA; Marks PA; Richon VM; Pandolfi PP
J Clin Invest; 2001 Nov; 108(9):1321-30. PubMed ID: 11696577
[TBL] [Abstract][Full Text] [Related]
20. Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways.
Dong S; Tweardy DJ
Blood; 2002 Apr; 99(8):2637-46. PubMed ID: 11929748
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
