BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 9486662)

  • 1. Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of Gbetagamma subunit, Src family, and Ras in cardiac fibroblasts.
    Zou Y; Komuro I; Yamazaki T; Kudoh S; Aikawa R; Zhu W; Shiojima I; Hiroi Y; Tobe K; Kadowaki T; Yazaki Y
    Circ Res; 1998 Feb; 82(3):337-45. PubMed ID: 9486662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of calcium-sensitive tyrosine kinase Pyk2/CAKbeta/RAFTK in angiotensin II induced Ras/ERK signaling.
    Murasawa S; Mori Y; Nozawa Y; Masaki H; Maruyama K; Tsutsumi Y; Moriguchi Y; Shibasaki Y; Tanaka Y; Iwasaka T; Inada M; Matsubara H
    Hypertension; 1998 Oct; 32(4):668-75. PubMed ID: 9774361
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes.
    Sadoshima J; Izumo S
    EMBO J; 1996 Feb; 15(4):775-87. PubMed ID: 8631299
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes.
    Zou Y; Komuro I; Yamazaki T; Aikawa R; Kudoh S; Shiojima I; Hiroi Y; Mizuno T; Yazaki Y
    J Biol Chem; 1996 Dec; 271(52):33592-7. PubMed ID: 8969227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling.
    Sadoshima J; Qiu Z; Morgan JP; Izumo S
    Circ Res; 1995 Jan; 76(1):1-15. PubMed ID: 8001266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats.
    Aikawa R; Komuro I; Yamazaki T; Zou Y; Kudoh S; Tanaka M; Shiojima I; Hiroi Y; Yazaki Y
    J Clin Invest; 1997 Oct; 100(7):1813-21. PubMed ID: 9312182
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy.
    Zou Y; Komuro I; Yamazaki T; Kudoh S; Uozumi H; Kadowaki T; Yazaki Y
    J Biol Chem; 1999 Apr; 274(14):9760-70. PubMed ID: 10092665
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases.
    Luttrell LM; Hawes BE; van Biesen T; Luttrell DK; Lansing TJ; Lefkowitz RJ
    J Biol Chem; 1996 Aug; 271(32):19443-50. PubMed ID: 8702633
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro.
    Aoki H; Richmond M; Izumo S; Sadoshima J
    Biochem J; 2000 Apr; 347 Pt 1(Pt 1):275-84. PubMed ID: 10727428
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway.
    Li X; Lee JW; Graves LM; Earp HS
    EMBO J; 1998 May; 17(9):2574-83. PubMed ID: 9564040
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation.
    Shah BH; Catt KJ
    Mol Pharmacol; 2002 Feb; 61(2):343-51. PubMed ID: 11809859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation.
    Luttrell LM; Della Rocca GJ; van Biesen T; Luttrell DK; Lefkowitz RJ
    J Biol Chem; 1997 Feb; 272(7):4637-44. PubMed ID: 9020193
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypertrophic responses of cardiomyocytes induced by endothelin-1 through the protein kinase C-dependent but Src and Ras-independent pathways.
    Yamazaki T; Komuro I; Zou Y; Yazaki Y
    Hypertens Res; 1999 Jul; 22(2):113-9. PubMed ID: 10487327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rho family small G proteins play critical roles in mechanical stress-induced hypertrophic responses in cardiac myocytes.
    Aikawa R; Komuro I; Yamazaki T; Zou Y; Kudoh S; Zhu W; Kadowaki T; Yazaki Y
    Circ Res; 1999 Mar; 84(4):458-66. PubMed ID: 10066681
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor.
    Murasawa S; Mori Y; Nozawa Y; Gotoh N; Shibuya M; Masaki H; Maruyama K; Tsutsumi Y; Moriguchi Y; Shibazaki Y; Tanaka Y; Iwasaka T; Inada M; Matsubara H
    Circ Res; 1998 Jun; 82(12):1338-48. PubMed ID: 9648731
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Signalling pathways for cardiac hypertrophy.
    Yamazaki T; Komuro I; Yazaki Y
    Cell Signal; 1998 Nov; 10(10):693-8. PubMed ID: 9884020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs.
    Seta K; Nanamori M; Modrall JG; Neubig RR; Sadoshima J
    J Biol Chem; 2002 Mar; 277(11):9268-77. PubMed ID: 11777928
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase.
    Della Rocca GJ; van Biesen T; Daaka Y; Luttrell DK; Luttrell LM; Lefkowitz RJ
    J Biol Chem; 1997 Aug; 272(31):19125-32. PubMed ID: 9235901
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc.
    Kranenburg O; Verlaan I; Hordijk PL; Moolenaar WH
    EMBO J; 1997 Jun; 16(11):3097-105. PubMed ID: 9214627
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Angiotensin II type 2 receptor-dependent increases in nitric oxide synthase expression in the pulmonary endothelium is mediated via a G alpha i3/Ras/Raf/MAPK pathway.
    Li J; Zhao X; Li X; Lerea KM; Olson SC
    Am J Physiol Cell Physiol; 2007 Jun; 292(6):C2185-96. PubMed ID: 17329403
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.