BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

624 related articles for article (PubMed ID: 9486667)

  • 1. Molecular determinants of dofetilide block of HERG K+ channels.
    Ficker E; Jarolimek W; Kiehn J; Baumann A; Brown AM
    Circ Res; 1998 Feb; 82(3):386-95. PubMed ID: 9486667
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.
    Ficker E; Jarolimek W; Brown AM
    Mol Pharmacol; 2001 Dec; 60(6):1343-8. PubMed ID: 11723241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.
    Kiehn J; Lacerda AE; Wible B; Brown AM
    Circulation; 1996 Nov; 94(10):2572-9. PubMed ID: 8921803
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of block and identification of the verapamil binding domain to HERG potassium channels.
    Zhang S; Zhou Z; Gong Q; Makielski JC; January CT
    Circ Res; 1999 May; 84(9):989-98. PubMed ID: 10325236
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High affinity open channel block by dofetilide of HERG expressed in a human cell line.
    Snyders DJ; Chaudhary A
    Mol Pharmacol; 1996 Jun; 49(6):949-55. PubMed ID: 8649354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
    Thomas D; Wendt-Nordahl G; Röckl K; Ficker E; Brown AM; Kiehn J
    J Pharmacol Exp Ther; 2001 May; 297(2):753-61. PubMed ID: 11303067
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dofetilide block involves interactions with open and inactivated states of HERG channels.
    Weerapura M; Hébert TE; Nattel S
    Pflugers Arch; 2002 Feb; 443(4):520-31. PubMed ID: 11907818
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels.
    Park JB; Choe H; Lee YK; Ha KC; Rhee KS; Ko JK; Joo CU; Chae SW; Kwak YG
    J Pharmacol Exp Ther; 2002 Jul; 302(1):314-9. PubMed ID: 12065732
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels.
    Kiehn J; Thomas D; Karle CA; Schöls W; Kübler W
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Mar; 359(3):212-9. PubMed ID: 10208308
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
    Dong DL; Li Z; Wang HZ; Du ZM; Song WH; Yang BF
    Basic Clin Pharmacol Toxicol; 2004 May; 94(5):209-12. PubMed ID: 15125690
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides.
    Spector PS; Curran ME; Keating MT; Sanguinetti MC
    Circ Res; 1996 Mar; 78(3):499-503. PubMed ID: 8593709
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [3H]dofetilide binding in SHSY5Y and HEK293 cells expressing a HERG-like K+ channel?
    Finlayson K; Pennington AJ; Kelly JS
    Eur J Pharmacol; 2001 Feb; 412(3):203-12. PubMed ID: 11166283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Open channel block of HERG K(+) channels by vesnarinone.
    Kamiya K; Mitcheson JS; Yasui K; Kodama I; Sanguinetti MC
    Mol Pharmacol; 2001 Aug; 60(2):244-53. PubMed ID: 11455010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241.
    Suessbrich H; Schönherr R; Heinemann SH; Lang F; Busch AE
    FEBS Lett; 1997 Sep; 414(2):435-8. PubMed ID: 9315735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o.
    Diaz GJ; Daniell K; Leitza ST; Martin RL; Su Z; McDermott JS; Cox BF; Gintant GA
    J Pharmacol Toxicol Methods; 2004; 50(3):187-99. PubMed ID: 15519905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
    Rampe D; Roy ML; Dennis A; Brown AM
    FEBS Lett; 1997 Nov; 417(1):28-32. PubMed ID: 9395068
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation.
    Ulens C; Tytgat J
    FEBS Lett; 2000 May; 474(1):111-5. PubMed ID: 10828461
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.
    Sanguinetti MC; Xu QP
    J Physiol; 1999 Feb; 514 ( Pt 3)(Pt 3):667-75. PubMed ID: 9882738
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.
    Chen J; Seebohm G; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12461-6. PubMed ID: 12209010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels.
    Herzberg IM; Trudeau MC; Robertson GA
    J Physiol; 1998 Aug; 511 ( Pt 1)(Pt 1):3-14. PubMed ID: 9679158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.