BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

332 related articles for article (PubMed ID: 9488469)

  • 1. Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells.
    Kim H; Hawley TS; Hawley RG; Baumann H
    Mol Cell Biol; 1998 Mar; 18(3):1525-33. PubMed ID: 9488469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
    Kim H; Baumann H
    Mol Cell Biol; 1999 Aug; 19(8):5326-38. PubMed ID: 10409724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells.
    Halfter H; Postert C; Friedrich M; Ringelstein EB; Stögbauer F
    Brain Res Mol Brain Res; 2000 Sep; 80(2):198-206. PubMed ID: 11038252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
    J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression.
    Symes A; Stahl N; Reeves SA; Farruggella T; Servidei T; Gearan T; Yancopoulos G; Fink JS
    Curr Biol; 1997 Sep; 7(9):697-700. PubMed ID: 9285712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The STAT3-independent signaling pathway by glycoprotein 130 in hepatic cells.
    Lai CF; Ripperger J; Wang Y; Kim H; Hawley RB; Baumann H
    J Biol Chem; 1999 Mar; 274(12):7793-802. PubMed ID: 10075671
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Desensitization of signaling by oncostatin M in human vascular cells involves cytoplasmic Tyr residue 759 in gp130 but is not mediated by either Src homology 2 domain-containing tyrosine phosphatase 2 or suppressor of cytokine signaling 3.
    Mahboubi K; Kirkiles-Smith NC; Karras J; Pober JS
    J Biol Chem; 2003 Jul; 278(27):25014-23. PubMed ID: 12724316
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130.
    Nicholson SE; De Souza D; Fabri LJ; Corbin J; Willson TA; Zhang JG; Silva A; Asimakis M; Farley A; Nash AD; Metcalf D; Hilton DJ; Nicola NA; Baca M
    Proc Natl Acad Sci U S A; 2000 Jun; 97(12):6493-8. PubMed ID: 10829066
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.
    Jenkins BJ; Grail D; Inglese M; Quilici C; Bozinovski S; Wong P; Ernst M
    Mol Cell Biol; 2004 Feb; 24(4):1453-63. PubMed ID: 14749363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130.
    Hermanns HM; Radtke S; Haan C; Schmitz-Van de Leur H; Tavernier J; Heinrich PC; Behrmann I
    J Immunol; 1999 Dec; 163(12):6651-8. PubMed ID: 10586060
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L; Maassen BG; Radtke S; Behrmann I; Schaper F; Heinrich PC; Graeve L; Gatsios P
    FEBS Lett; 2000 Jul; 478(1-2):100-4. PubMed ID: 10922477
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.
    Lehmann U; Schmitz J; Weissenbach M; Sobota RM; Hortner M; Friederichs K; Behrmann I; Tsiaris W; Sasaki A; Schneider-Mergener J; Yoshimura A; Neel BG; Heinrich PC; Schaper F
    J Biol Chem; 2003 Jan; 278(1):661-71. PubMed ID: 12403768
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy.
    Podewski EK; Hilfiker-Kleiner D; Hilfiker A; Morawietz H; Lichtenberg A; Wollert KC; Drexler H
    Circulation; 2003 Feb; 107(6):798-802. PubMed ID: 12591746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.
    Kim HY; Park EJ; Joe EH; Jou I
    J Immunol; 2003 Dec; 171(11):6072-9. PubMed ID: 14634121
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of hepatic acute phase gene expression by epidermal growth factor and Src protein tyrosine kinases in murine and human hepatic cells.
    Wang Y; Ripperger J; Fey GH; Samols D; Kordula T; Wetzler M; Van Etten RA; Baumann H
    Hepatology; 1999 Sep; 30(3):682-97. PubMed ID: 10462375
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1.
    Kortylewski M; Heinrich PC; Mackiewicz A; Schniertshauer U; Klingmüller U; Nakajima K; Hirano T; Horn F; Behrmann I
    Oncogene; 1999 Jun; 18(25):3742-53. PubMed ID: 10391682
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling.
    Yu WM; Hawley TS; Hawley RG; Qu CK
    Oncogene; 2003 Sep; 22(38):5995-6004. PubMed ID: 12955078
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Receptor subunit-specific action of oncostatin M in hepatic cells and its modulation by leukemia inhibitory factor.
    Wang Y; Robledo O; Kinzie E; Blanchard F; Richards C; Miyajima A; Baumann H
    J Biol Chem; 2000 Aug; 275(33):25273-85. PubMed ID: 10854424
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation.
    Anhuf D; Weissenbach M; Schmitz J; Sobota R; Hermanns HM; Radtke S; Linnemann S; Behrmann I; Heinrich PC; Schaper F
    J Immunol; 2000 Sep; 165(5):2535-43. PubMed ID: 10946280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.