BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 9488713)

  • 1. Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies.
    Sakai J; Nohturfft A; Goldstein JL; Brown MS
    J Biol Chem; 1998 Mar; 273(10):5785-93. PubMed ID: 9488713
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein.
    Sakai J; Nohturfft A; Cheng D; Ho YK; Brown MS; Goldstein JL
    J Biol Chem; 1997 Aug; 272(32):20213-21. PubMed ID: 9242699
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane.
    Hua X; Sakai J; Brown MS; Goldstein JL
    J Biol Chem; 1996 Apr; 271(17):10379-84. PubMed ID: 8626610
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi.
    Nohturfft A; DeBose-Boyd RA; Scheek S; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11235-40. PubMed ID: 10500160
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.
    Nohturfft A; Brown MS; Goldstein JL
    Proc Natl Acad Sci U S A; 1998 Oct; 95(22):12848-53. PubMed ID: 9789003
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of membrane domain of SCAP prevents sterols from inhibiting SCAP.SREBP exit from endoplasmic reticulum.
    Yang T; Goldstein JL; Brown MS
    J Biol Chem; 2000 Sep; 275(38):29881-6. PubMed ID: 10896675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).
    Korn BS; Shimomura I; Bashmakov Y; Hammer RE; Horton JD; Goldstein JL; Brown MS
    J Clin Invest; 1998 Dec; 102(12):2050-60. PubMed ID: 9854040
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor.
    Heemers H; Verrijdt G; Organe S; Claessens F; Heyns W; Verhoeven G; Swinnen JV
    J Biol Chem; 2004 Jul; 279(29):30880-7. PubMed ID: 15133039
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.
    Duncan EA; Brown MS; Goldstein JL; Sakai J
    J Biol Chem; 1997 May; 272(19):12778-85. PubMed ID: 9139737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins.
    Zelenski NG; Rawson RB; Brown MS; Goldstein JL
    J Biol Chem; 1999 Jul; 274(31):21973-80. PubMed ID: 10419520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.
    Rawson RB; DeBose-Boyd R; Goldstein JL; Brown MS
    J Biol Chem; 1999 Oct; 274(40):28549-56. PubMed ID: 10497220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1).
    Sato R; Yang J; Wang X; Evans MJ; Ho YK; Goldstein JL; Brown MS
    J Biol Chem; 1994 Jun; 269(25):17267-73. PubMed ID: 8006035
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi.
    DeBose-Boyd RA; Brown MS; Li WP; Nohturfft A; Goldstein JL; Espenshade PJ
    Cell; 1999 Dec; 99(7):703-12. PubMed ID: 10619424
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
    Yang T; Espenshade PJ; Wright ME; Yabe D; Gong Y; Aebersold R; Goldstein JL; Brown MS
    Cell; 2002 Aug; 110(4):489-500. PubMed ID: 12202038
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.
    Yabe D; Xia ZP; Adams CM; Rawson RB
    Proc Natl Acad Sci U S A; 2002 Dec; 99(26):16672-7. PubMed ID: 12482938
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.
    Sun LP; Li L; Goldstein JL; Brown MS
    J Biol Chem; 2005 Jul; 280(28):26483-90. PubMed ID: 15899885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins.
    Weber LW; Boll M; Stampfl A
    World J Gastroenterol; 2004 Nov; 10(21):3081-7. PubMed ID: 15457548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element.
    Hua X; Yokoyama C; Wu J; Briggs MR; Brown MS; Goldstein JL; Wang X
    Proc Natl Acad Sci U S A; 1993 Dec; 90(24):11603-7. PubMed ID: 7903453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis.
    Wang X; Zelenski NG; Yang J; Sakai J; Brown MS; Goldstein JL
    EMBO J; 1996 Mar; 15(5):1012-20. PubMed ID: 8605870
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins.
    MagaƱa MM; Lin SS; Dooley KA; Osborne TF
    J Lipid Res; 1997 Aug; 38(8):1630-8. PubMed ID: 9300785
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.