BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 9491793)

  • 1. Cytotoxicity and intracellular biotransformation of N-benzyladriamycin-14-valerate (AD 198) are modulated by changes in 14-O-acyl chain length.
    Lothstein L; Rodrigues PJ; Sweatman TW; Israel M
    Anticancer Drugs; 1998 Jan; 9(1):58-66. PubMed ID: 9491793
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-benzyladriamycin-14-valerate (AD 198)-resistant cells exhibit highly selective cross-resistance to other anthracyclines that circumvent multidrug resistance.
    Lothstein L; Hosey LM; Sweatman TW; Koseki Y; Dockter M; Priebe W
    Oncol Res; 1993; 5(6-7):229-34. PubMed ID: 7907237
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacology of N,N-di(n-butyl)adriamycin-14-valerate in the rat.
    Han G; Israel M; Seshadri R; Dalton JT; Sweatman TW
    Cancer Chemother Pharmacol; 1996; 37(5):472-8. PubMed ID: 8599871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resistance to N-benzyladriamycin-14-valerate in mouse J774.2 cells: P-glycoprotein expression without reduced N-benzyladriamycin-14-valerate accumulation.
    Lothstein L; Sweatman TW; Dockter ME; Israel M
    Cancer Res; 1992 Jun; 52(12):3409-17. PubMed ID: 1350753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N-benzyladriamycin-14-valerate and drug resistance: correlation of anthracycline structural modification with intracellular accumulation and distribution in multidrug resistant cells.
    Lothstein L; Wright HM; Sweatman TW; Israel M
    Oncol Res; 1992; 4(8-9):341-7. PubMed ID: 1362503
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacology of N-benzyladriamycin-14-valerate in the rat.
    Sweatman TW; Seshadri R; Israel M
    Cancer Chemother Pharmacol; 1999; 43(5):419-26. PubMed ID: 10100599
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative uptake and retention of adriamycin and N-benzyladriamycin-14-valerate in human CEM leukemic lymphocyte cell cultures.
    Israel M; Sweatman TW; Seshadri R; Koseki Y
    Cancer Chemother Pharmacol; 1989; 25(3):177-83. PubMed ID: 2598408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction of the novel anthracycline antitumor agent N-benzyladriamycin-14-valerate with the C1-regulatory domain of protein kinase C: structural requirements, isoform specificity, and correlation with drug cytotoxicity.
    Roaten JB; Kazanietz MG; Caloca MJ; Bertics PJ; Lothstein L; Parrill AL; Israel M; Sweatman TW
    Mol Cancer Ther; 2002 May; 1(7):483-92. PubMed ID: 12479266
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P-glycoprotein overexpression in mouse cells does not correlate with resistance to N-benzyladriamycin-14-valerate (AD 198).
    Lothstein L; Koseki Y; Sweatman TW
    Anticancer Drugs; 1994 Dec; 5(6):623-33. PubMed ID: 7888699
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular models of N-benzyladriamycin-14-valerate (AD 198) in complex with the phorbol ester-binding C1b domain of protein kinase C-delta.
    Roaten JB; Kazanietz MG; Sweatman TW; Lothstein L; Israel M; Parrill AL
    J Med Chem; 2001 Mar; 44(7):1028-34. PubMed ID: 11297449
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA topoisomerase II-mediated interaction of doxorubicin and daunorubicin congeners with DNA.
    Bodley A; Liu LF; Israel M; Seshadri R; Koseki Y; Giuliani FC; Kirschenbaum S; Silber R; Potmesil M
    Cancer Res; 1989 Nov; 49(21):5969-78. PubMed ID: 2551497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Catalytic inhibition of DNA topoisomerase II by N-benzyladriamycin (AD 288).
    Lothstein L; Suttle DP; Roaten JB; Koseki Y; Israel M; Sweatman TW
    Biochem Pharmacol; 2000 Dec; 60(11):1621-8. PubMed ID: 11077044
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of new N-alkyl analogues of adriamycin on in vitro survival and cell cycle progression of L1210 cells.
    Traganos F; Israel M; Silber R; Seshadri R; Kirschenbaum S; Potmesil M
    Cancer Res; 1985 Dec; 45(12 Pt 1):6273-9. PubMed ID: 4063977
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cellular resistance against the novel hybrid anthracycline N-(2-chloroethyl)-N-nitrosoureidodaunorubicin (AD 312) is mediated by combined altered topoisomerase II and O6-methylguanine-DNA methyltransferase activities.
    Pawlik CA; Israel M; Sweatman TW; Lothstein L
    Oncol Res; 1998; 10(4):209-17. PubMed ID: 9778692
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-Benzyladriamycin-14-valerate (AD 198) cytotoxicty circumvents Bcr-Abl anti-apoptotic signaling in human leukemia cells and also potentiates imatinib cytotoxicity.
    Lothstein L; Savranskaya L; Sweatman TW
    Leuk Res; 2007 Aug; 31(8):1085-95. PubMed ID: 17187856
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-benzyladriamycin-14-valerate versus progressively doxorubicin-resistant murine tumours: cellular pharmacology and characterisation of cross-resistance in vitro and in vivo.
    Ganapathi R; Grabowski D; Sweatman TW; Seshadri R; Israel M
    Br J Cancer; 1989 Dec; 60(6):819-26. PubMed ID: 2605093
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic studies on N-benzyladriamycin-14-valerate (AD 198), a highly lipophilic alkyl adriamycin analog.
    Lameh J; Chuang LF; Israel M; Chuang RY
    Anticancer Res; 1988; 8(4):689-93. PubMed ID: 3052250
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anthracycline-induced DNA breaks and resealing in doxorubicin-resistant murine leukemic P388 cells.
    Maniar N; Krishan A; Israel M; Samy TS
    Biochem Pharmacol; 1988 May; 37(9):1763-72. PubMed ID: 2837239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Benzyladriamycin-14-valerate (AD 198): a non-cardiotoxic anthracycline that is cardioprotective through PKC-epsilon activation.
    Hofmann PA; Israel M; Koseki Y; Laskin J; Gray J; Janik A; Sweatman TW; Lothstein L
    J Pharmacol Exp Ther; 2007 Nov; 323(2):658-64. PubMed ID: 17693586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protection against Adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity by 3,4-dihydroxybenzoic acid.
    De Graff WG; Myers LS; Mitchell JB; Hahn SM
    Int J Oncol; 2003 Jul; 23(1):159-63. PubMed ID: 12792789
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.