These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 9492845)

  • 1. Treatment of human prostate cancer cells with dolastatin 10, a peptide isolated from a marine shell-less mollusc.
    Turner T; Jackson WH; Pettit GR; Wells A; Kraft AS
    Prostate; 1998 Feb; 34(3):175-81. PubMed ID: 9492845
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumour evaluation of dolastatins 10 and 15 and their measurement in plasma by radioimmunoassay.
    Aherne GW; Hardcastle A; Valenti M; Bryant A; Rogers P; Pettit GR; Srirangam JK; Kelland LR
    Cancer Chemother Pharmacol; 1996; 38(3):225-32. PubMed ID: 8646796
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
    Bai R; Friedman SJ; Pettit GR; Hamel E
    Biochem Pharmacol; 1992 Jun; 43(12):2637-45. PubMed ID: 1632820
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor activity of TZT-1027, a novel dolastatin 10 derivative.
    Kobayashi M; Natsume T; Tamaoki S; Watanabe J; Asano H; Mikami T; Miyasaka K; Miyazaki K; Gondo M; Sakakibara K; Tsukagoshi S
    Jpn J Cancer Res; 1997 Mar; 88(3):316-27. PubMed ID: 9140117
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Growth inhibition of human lymphoma cell lines by the marine products, dolastatins 10 and 15.
    Beckwith M; Urba WJ; Longo DL
    J Natl Cancer Inst; 1993 Mar; 85(6):483-8. PubMed ID: 8445676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
    Bai R; Pettit GR; Hamel E
    Biochem Pharmacol; 1990 Jun; 39(12):1941-9. PubMed ID: 2353935
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity.
    Bai R; Roach MC; Jayaram SK; Barkoczy J; Pettit GR; Ludueña RF; Hamel E
    Biochem Pharmacol; 1993 Apr; 45(7):1503-15. PubMed ID: 8471072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10.
    Bai RL; Pettit GR; Hamel E
    Biochem Pharmacol; 1990 Oct; 40(8):1859-64. PubMed ID: 2242019
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antineoplastic agents 365. Dolastatin 10 SAR probes.
    Pettit GR; Srirangam JK; Barkoczy J; Williams MD; Boyd MR; Hamel E; Pettit RK; Hogan F; Bai R; Chapuis JC; McAllister SC; Schmidt JM
    Anticancer Drug Des; 1998 Jun; 13(4):243-77. PubMed ID: 9627667
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of marine toxin dolastatin 10 with porcine brain tubulin: competitive inhibition of rhizoxin and phomopsin A binding.
    Li Y; Kobayashi H; Hashimoto Y; Shirai R; Hirata A; Hayashi K; Hamada Y; Shioiri T; Iwasaki S
    Chem Biol Interact; 1994 Dec; 93(3):175-83. PubMed ID: 7923438
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new tubulin polymerization inhibitor, auristatin PE, induces tumor regression in a human Waldenstrom's macroglobulinemia xenograft model.
    Mohammad RM; Limvarapuss C; Wall NR; Hamdy N; Beck FW; Pettit GR; Al-Katib A
    Int J Oncol; 1999 Aug; 15(2):367-72. PubMed ID: 10402249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Successful treatment of human chronic lymphocytic leukemia xenografts with combination biological agents auristatin PE and bryostatin 1.
    Mohammad RM; Varterasian ML; Almatchy VP; Hannoudi GN; Pettit GR; Al-Katib A
    Clin Cancer Res; 1998 May; 4(5):1337-43. PubMed ID: 9607595
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antineoplastic agents 337. Synthesis of dolastatin 10 structural modifications.
    Pettit GR; Srirangam JK; Barkoczy J; Williams MD; Durkin KP; Boyd MR; Bai R; Hamel E; Schmidt JM; Chapuis JC
    Anticancer Drug Des; 1995 Oct; 10(7):529-44. PubMed ID: 7495477
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dolastatin 15 induces apoptosis and BCL-2 phosphorylation in small cell lung cancer cell lines.
    Ali MA; Rosati R; Pettit GR; Kalemkerian GP
    Anticancer Res; 1998; 18(2A):1021-6. PubMed ID: 9615758
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A natural peptide, dolastatin 15, induces G2/M cell cycle arrest and apoptosis of human multiple myeloma cells.
    Sato M; Sagawa M; Nakazato T; Ikeda Y; Kizaki M
    Int J Oncol; 2007 Jun; 30(6):1453-9. PubMed ID: 17487366
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification.
    Kalemkerian GP; Ou X; Adil MR; Rosati R; Khoulani MM; Madan SK; Pettit GR
    Cancer Chemother Pharmacol; 1999; 43(6):507-15. PubMed ID: 10321512
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10.
    Edler MC; Fernandez AM; Lassota P; Ireland CM; Barrows LR
    Biochem Pharmacol; 2002 Feb; 63(4):707-15. PubMed ID: 11992639
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
    Cruz-Monserrate Z; Vervoort HC; Bai R; Newman DJ; Howell SB; Los G; Mullaney JT; Williams MD; Pettit GR; Fenical W; Hamel E
    Mol Pharmacol; 2003 Jun; 63(6):1273-80. PubMed ID: 12761336
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of Dolastatin 15 mimetic peptoids.
    Schmitt J; Bernd M; Kutscher B; Kessler H
    Bioorg Med Chem Lett; 1998 Feb; 8(4):385-8. PubMed ID: 9871690
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and cytostatic properties of structure-simplified analogs of dolastatin 15.
    Hu MK; Huang WS
    J Pept Res; 1999 Dec; 54(6):460-7. PubMed ID: 10604591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.