64 related articles for article (PubMed ID: 9495849)
1. Pharmacokinetic and pharmacodynamic study of a new nonsteroidal 5 alpha-reductase inhibitor, 4-[3-[3-[Bis(4-isobutylphenyl)methylamino]benzoyl]-1H-indol-1-yl]-butyr ic acid, in rats.
Katashima M; Yamamoto K; Tokuma Y; Hata T; Sawada Y; Iga T
J Pharmacol Exp Ther; 1998 Mar; 284(3):914-20. PubMed ID: 9495849
[TBL] [Abstract][Full Text] [Related]
2. Tissue distribution kinetics of a new nonsteroidal 5 alpha-reductase [correction of 5 A-reductase] inhibitor, 4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]-1H-indol-1-YL ]-butyric acid, in rats.
Katashima M; Yamamoto K; Haraguchi K; Tokuma Y; Hata T; Sawada Y; Iga T
Drug Metab Dispos; 1997 Sep; 25(9):1051-8. PubMed ID: 9311620
[TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetics and pharmacodynamics of FK143, a nonsteroidal inhibitor of steroid 5 alpha-reductase, in healthy volunteers.
Katashima M; Irino T; Shimojo F; Kawamura A; Kageyama H; Higashi N; Miyao Y; Tokuma Y; Hata T; Yamamoto K; Sawada Y; Iga T
Clin Pharmacol Ther; 1998 Mar; 63(3):354-66. PubMed ID: 9542479
[TBL] [Abstract][Full Text] [Related]
4. Novel steroid 5 alpha-reductase inhibitor FK143: its dual inhibition against the two isozymes and its effect on transcription of the isozyme genes.
Kojo H; Nakayama O; Hirosumi J; Chida N; Notsu Y; Okuhara M
Mol Pharmacol; 1995 Sep; 48(3):401-6. PubMed ID: 7565619
[TBL] [Abstract][Full Text] [Related]
5. Preventive effect of FK143, a 5alpha-reductase inhibitor, on chemical hepatocarcinogenesis in rats.
Maruyama S; Nagasue N; Dhar DK; Yamanoi A; El-Assal ON; Satoh K; Okita K
Clin Cancer Res; 2001 Jul; 7(7):2096-104. PubMed ID: 11448929
[TBL] [Abstract][Full Text] [Related]
6. FK143, a novel nonsteroidal inhibitor of steroid 5 alpha-reductase: (2) In vivo effects on rat and dog prostates.
Hirosumi J; Nakayama O; Chida N; Inami M; Fagan T; Sawada K; Shigematsu S; Kojo H; Notsu Y; Okuhara M
J Steroid Biochem Mol Biol; 1995 Apr; 52(4):365-73. PubMed ID: 7734405
[TBL] [Abstract][Full Text] [Related]
7. 4-(1-benzoylindol-3-yl)butyric acids and FK143: novel nonsteroidal inhibitors of steroid 5 alpha-reductase (II).
Sawada K; Okada S; Golden P; Kayakiri N; Sawada Y; Hashimoto M; Tanaka H
Chem Pharm Bull (Tokyo); 1999 Apr; 47(4):481-91. PubMed ID: 10319427
[TBL] [Abstract][Full Text] [Related]
8. Effects of a new non-steroidal 5 alpha-reductase inhibitor, FK143, on the prostate gland in beagle dogs.
Inami M; Kawamura I; Naoe Y; Tsujimoto S; Mizota T; Manda T; Shimomura K
Jpn J Pharmacol; 1997 Jun; 74(2):187-94. PubMed ID: 9243327
[TBL] [Abstract][Full Text] [Related]
9. Region-specific expression of androgen and growth factor pathway genes in the rat epididymis and the effects of dual 5alpha-reductase inhibition.
Henderson NA; Cooke GM; Robaire B
J Endocrinol; 2006 Sep; 190(3):779-91. PubMed ID: 17003279
[TBL] [Abstract][Full Text] [Related]
10. FK143, a novel nonsteroidal inhibitor of steroid 5 alpha-reductase: (1) In vitro effects on human and animal prostatic enzymes.
Hirosumi J; Nakayama O; Fagan T; Sawada K; Chida N; Inami M; Takahashi S; Kojo H; Notsu Y; Okuhara M
J Steroid Biochem Mol Biol; 1995 Apr; 52(4):357-63. PubMed ID: 7734404
[TBL] [Abstract][Full Text] [Related]
11. Z-350, a novel compound with alpha 1-adrenoceptor antagonistic and steroid 5 alpha-reductase inhibitory actions: pharmacological properties in vivo.
Fukuta Y; Fukuda Y; Higashino R; Yoshida K; Ogishima M; Tamaki H; Takei M
J Pharmacol Exp Ther; 1999 Sep; 290(3):1013-8. PubMed ID: 10454472
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of rat prostate carcinogenesis by a 5alpha-reductase inhibitor, FK143.
Homma Y; Kaneko M; Kondo Y; Kawabe K; Kakizoe T
J Natl Cancer Inst; 1997 Jun; 89(11):803-7. PubMed ID: 9182979
[TBL] [Abstract][Full Text] [Related]
13. Actions of 5alpha-reductase inhibitors on the epididymis.
Robaire B; Henderson NA
Mol Cell Endocrinol; 2006 May; 250(1-2):190-5. PubMed ID: 16476520
[TBL] [Abstract][Full Text] [Related]
14. Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors.
Takami H; Koshimura H; Kishibayashi N; Ishii A; Nonaka H; Aoyama S; Kase H; Kumazawa T
J Med Chem; 1996 Dec; 39(26):5047-52. PubMed ID: 8978835
[TBL] [Abstract][Full Text] [Related]
15. A model for the turnover of dihydrotestosterone in the presence of the irreversible 5 alpha-reductase inhibitors GI198745 and finasteride.
Gisleskog PO; Hermann D; Hammarlund-Udenaes M; Karlsson MO
Clin Pharmacol Ther; 1998 Dec; 64(6):636-47. PubMed ID: 9871428
[TBL] [Abstract][Full Text] [Related]
16. Radioligand exchange binding cannot directly determine the dissociation constant (Kd) of the rat ventral prostate nuclear androgen receptor: valid Kd determinations require additional uptake binding data.
Chapman JC; Freeh SM; Michael SD
Arch Biochem Biophys; 1993 Dec; 307(2):242-7. PubMed ID: 8274009
[TBL] [Abstract][Full Text] [Related]
17. A novel in vitro model to screen steroid 5 alpha-reductase inhibitors against benign prostatic hyperplasia.
Sun ZY; Tu ZH
Methods Find Exp Clin Pharmacol; 1998 May; 20(4):283-7. PubMed ID: 9658376
[TBL] [Abstract][Full Text] [Related]
18. Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
Xu Y; Dalrymple SL; Becker RE; Denmeade SR; Isaacs JT
Clin Cancer Res; 2006 Jul; 12(13):4072-9. PubMed ID: 16818707
[TBL] [Abstract][Full Text] [Related]
19. Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers.
Bergman AJ; Stevens C; Zhou Y; Yi B; Laethem M; De Smet M; Snyder K; Hilliard D; Tanaka W; Zeng W; Tanen M; Wang AQ; Chen L; Winchell G; Davies MJ; Ramael S; Wagner JA; Herman GA
Clin Ther; 2006 Jan; 28(1):55-72. PubMed ID: 16490580
[TBL] [Abstract][Full Text] [Related]
20. Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line.
Lazier CB; Thomas LN; Douglas RC; Vessey JP; Rittmaster RS
Prostate; 2004 Feb; 58(2):130-44. PubMed ID: 14716738
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]