154 related articles for article (PubMed ID: 9498271)
1. The DNA damaging drug cyproterone acetate causes gene mutations and induces glutathione-S-transferase P in the liver of female Big Blue transgenic F344 rats.
Krebs O; Schäfer B; Wolff T; Oesterle D; Deml E; Sund M; Favor J
Carcinogenesis; 1998 Feb; 19(2):241-5. PubMed ID: 9498271
[TBL] [Abstract][Full Text] [Related]
2. No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part II. Multiple dose treatment.
Topinka J; Oesterle D; Reimann R; Wolff T
Mutat Res; 2004 Jun; 550(1-2):101-8. PubMed ID: 15135644
[TBL] [Abstract][Full Text] [Related]
3. No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part I. Single dose treatment.
Topinka J; Oesterle D; Reimann R; Wolff T
Mutat Res; 2004 Jun; 550(1-2):89-99. PubMed ID: 15135643
[TBL] [Abstract][Full Text] [Related]
4. Formation of DNA adducts by cyproterone acetate and some structural analogues in primary cultures of human hepatocytes.
Werner S; Kunz S; Beckurts T; Heidecke CD; Wolff T; Schwarz LR
Mutat Res; 1997 Dec; 395(2-3):179-87. PubMed ID: 9465929
[TBL] [Abstract][Full Text] [Related]
5. Dose dependent induction of DNA adducts, gene mutations, and cell proliferation by the antiandrogenic drug cyproterone acetate in rat liver.
Wolff T; Topinka J; Deml E; Oesterle D; Schwarz LR
Adv Exp Med Biol; 2001; 500():687-96. PubMed ID: 11765015
[TBL] [Abstract][Full Text] [Related]
6. Cyproterone acetate generates DNA adducts in rat liver and in primary rat hepatocyte cultures.
Topinka J; Andrae U; Schwarz LR; Wolff T
Carcinogenesis; 1993 Mar; 14(3):423-7. PubMed ID: 8453718
[TBL] [Abstract][Full Text] [Related]
7. DNA-damaging activity of the cyproterone acetate analogues chlormadinone acetate and megestrol acetate in rat liver.
Topinka J; Binkova B; Zhu HK; Andrae U; Neumann I; Schwarz LR; Werner S; Wolff T
Carcinogenesis; 1995 Jul; 16(7):1483-7. PubMed ID: 7542174
[TBL] [Abstract][Full Text] [Related]
8. Accumulation and persistence of DNA adducts of the synthetic steroid cyproterone acetate in rat liver.
Werner S; Topinka J; Wolff T; Schwarz LR
Carcinogenesis; 1995 Oct; 16(10):2369-72. PubMed ID: 7586137
[TBL] [Abstract][Full Text] [Related]
9. Dose-dependent formation of preneoplastic foci and DNA adducts in rat liver with 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alpha C) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Hasegawa R; Takahashi S; Shirai T; Iwasaki S; Kim DJ; Ochiai M; Nagao M; Sugimura T; Ito N
Carcinogenesis; 1992 Aug; 13(8):1427-31. PubMed ID: 1499093
[TBL] [Abstract][Full Text] [Related]
10. Cyproterone acetate: a genotoxic carcinogen?
Kasper P
Pharmacol Toxicol; 2001 May; 88(5):223-31. PubMed ID: 11393581
[TBL] [Abstract][Full Text] [Related]
11. Cyproterone acetate is an integral part of hepatic DNA adducts induced by this steroidal drug.
Topinka J; Binkova B; Schwarz LR; Wolff T
Carcinogenesis; 1996 Jan; 17(1):167-9. PubMed ID: 8565129
[TBL] [Abstract][Full Text] [Related]
12. Steroidal drug cyproterone acetate is activated to DNA-binding metabolites by sulfonation.
Werner S; Kunz S; Wolff T; Schwarz LR
Cancer Res; 1996 Oct; 56(19):4391-7. PubMed ID: 8813132
[TBL] [Abstract][Full Text] [Related]
13. In vitro mutagenicity studies on cyproterone acetate using female rat hepatocytes for metabolic activation and as indicator cells.
Kasper P; Tegethoff K; Mueller L
Carcinogenesis; 1995 Oct; 16(10):2309-14. PubMed ID: 7586127
[TBL] [Abstract][Full Text] [Related]
14. DNA adduct formation and T lymphocyte mutation induction in F344 rats implanted with tumorigenic doses of 1,6-dinitropyrene.
Beland FA
Res Rep Health Eff Inst; 1995 Oct; (72):1-27; discussion 29-39. PubMed ID: 11381742
[TBL] [Abstract][Full Text] [Related]
15. Sex-specific dose-response analysis of genotoxicity in cyproterone acetate-treated F344 rats.
Ding W; Bishop ME; Pearce MG; Davis KJ; White GA; Lyn-Cook LE; Manjanatha MG
Mutat Res Genet Toxicol Environ Mutagen; 2014 Nov; 774():1-7. PubMed ID: 25440904
[TBL] [Abstract][Full Text] [Related]
16. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
17. Initiation of enzyme-altered foci by the synthetic steroid cyproterone acetate in rat liver foci bioassay.
Deml E; Schwarz LR; Oesterle D
Carcinogenesis; 1993 Jun; 14(6):1229-31. PubMed ID: 8099540
[TBL] [Abstract][Full Text] [Related]
18. Time-related induction of DNA repair synthesis in rat hepatocytes following in vivo treatment with cyproterone acetate.
Kasper P; Mueller L
Carcinogenesis; 1996 Oct; 17(10):2271-4. PubMed ID: 8895500
[TBL] [Abstract][Full Text] [Related]
19. Long term phenobarbital administration does not promote the multiplication of hepatocytes replicating after single cyproterone acetate administration.
Pichard V; Ferry N
Life Sci; 2005 May; 76(26):3057-68. PubMed ID: 15850598
[TBL] [Abstract][Full Text] [Related]
20. Cyproterone acetate: is it hepato- or genotoxic?
Rabe T; Feldmann K; Heinemann L; Runnebaum B
Drug Saf; 1996 Jan; 14(1):25-38. PubMed ID: 8713486
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]