These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 9513603)

  • 1. Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity.
    McKittrick BA; Ma K; Huie K; Yumibe N; Davis H; Clader JW; Czarniecki M; McPhail AT
    J Med Chem; 1998 Feb; 41(5):752-9. PubMed ID: 9513603
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption.
    Kvaernø L; Werder M; Hauser H; Carreira EM
    J Med Chem; 2005 Sep; 48(19):6035-53. PubMed ID: 16162006
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of iodinated biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
    Burnett DA; Caplen MA; Domalski MS; Browne ME; Davis HR; Clader JW
    Bioorg Med Chem Lett; 2002 Feb; 12(3):311-4. PubMed ID: 11814785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A formal synthesis of ezetimibe via cycloaddition/rearrangement cascade reaction.
    Michalak M; Stodulski M; Stecko S; Mames A; Panfil I; Soluch M; Furman B; Chmielewski M
    J Org Chem; 2011 Aug; 76(16):6931-6. PubMed ID: 21744801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carboxy-substituted 2-azetidinones as cholesterol absorption inhibitors.
    Vaccaro WD; Sher R; Davis HR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):319-22. PubMed ID: 9871677
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heterocyclic ring scaffolds as small-molecule cholesterol absorption inhibitors.
    Ritter T; Kvaernø L; Werder M; Hauser H; Carreira EM
    Org Biomol Chem; 2005 Oct; 3(19):3514-23. PubMed ID: 16172689
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461.
    Van Heek M; France CF; Compton DS; McLeod RL; Yumibe NP; Alton KB; Sybertz EJ; Davis HR
    J Pharmacol Exp Ther; 1997 Oct; 283(1):157-63. PubMed ID: 9336320
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus.
    Clader JW; Burnett DA; Caplen MA; Domalski MS; Dugar S; Vaccaro W; Sher R; Browne ME; Zhao H; Burrier RE; Salisbury B; Davis HR
    J Med Chem; 1996 Sep; 39(19):3684-93. PubMed ID: 8809157
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Azetidinones as inhibitors of cholesterol absorption.
    Burnett DA; Caplen MA; Davis HR; Burrier RE; Clader JW
    J Med Chem; 1994 Jun; 37(12):1733-6. PubMed ID: 8021912
    [No Abstract]   [Full Text] [Related]  

  • 10. Substituted 2-azaspiro[5.3]nonan-1-ones as potent cholesterol absorption inhibitors: defining a binding conformation for SCH 48461.
    Dugar S; Clader JW; Chan TM; Davis H
    J Med Chem; 1995 Dec; 38(25):4875-7. PubMed ID: 8523398
    [No Abstract]   [Full Text] [Related]  

  • 11. Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.
    Rosenblum SB; Huynh T; Afonso A; Davis HR; Yumibe N; Clader JW; Burnett DA
    J Med Chem; 1998 Mar; 41(6):973-80. PubMed ID: 9526571
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Total synthesis of ezetimibe, a cholesterol absorption inhibitor.
    Śnieżek M; Stecko S; Panfil I; Furman B; Chmielewski M
    J Org Chem; 2013 Jul; 78(14):7048-57. PubMed ID: 23763523
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ezetimibe (Schering-Plough).
    Meng CQ
    Curr Opin Investig Drugs; 2001 Mar; 2(3):389-92. PubMed ID: 11575710
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of fluorescent biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
    Burnett DA; Caplen MA; Browne ME; Zhau H; Altmann SW; Davis HR; Clader JW
    Bioorg Med Chem Lett; 2002 Feb; 12(3):315-8. PubMed ID: 11814786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions.
    Xu X; Fu R; Chen J; Chen S; Bai X
    Bioorg Med Chem Lett; 2007 Jan; 17(1):101-4. PubMed ID: 17049851
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Spiroimidazolidinone NPC1L1 inhibitors. Part 2: structure-activity studies and in vivo efficacy.
    Howell KL; DeVita RJ; Garcia-Calvo M; Meurer RD; Lisnock J; Bull HG; McMasters DR; McCann ME; Mills SG
    Bioorg Med Chem Lett; 2010 Dec; 20(23):6929-32. PubMed ID: 21030254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sugar-substituted 2-azetidinones as cholesterol absorption inhibitors.
    Vaccaro WD; Sher R; Davis HR
    Bioorg Med Chem Lett; 1998 Jan; 8(1):35-40. PubMed ID: 9871624
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carbohydrate sulfonyl chlorides for simple, convenient access to glycoconjugates.
    Kvaernø L; Werder M; Hauser H; Carreira EM
    Org Lett; 2005 Mar; 7(6):1145-8. PubMed ID: 15760160
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2-Azetidinone derivatives: design, synthesis and evaluation of cholesterol absorption inhibitors.
    Wang Y; Zhang H; Huang W; Kong J; Zhou J; Zhang B
    Eur J Med Chem; 2009 Apr; 44(4):1638-43. PubMed ID: 18990470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sugar-substituted 2-azetidinone cholesterol absorption inhibitors: enhanced potency by modification of the sugar.
    Vaccaro WD; Davis HR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):313-8. PubMed ID: 9871676
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.