BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

385 related articles for article (PubMed ID: 9516432)

  • 1. The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.
    Dittmar KD; Banach M; Galigniana MD; Pratt WB
    J Biol Chem; 1998 Mar; 273(13):7358-66. PubMed ID: 9516432
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.
    Dittmar KD; Demady DR; Stancato LF; Krishna P; Pratt WB
    J Biol Chem; 1997 Aug; 272(34):21213-20. PubMed ID: 9261129
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation.
    Dittmar KD; Pratt WB
    J Biol Chem; 1997 May; 272(20):13047-54. PubMed ID: 9148915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.
    Dittmar KD; Hutchison KA; Owens-Grillo JK; Pratt WB
    J Biol Chem; 1996 May; 271(22):12833-9. PubMed ID: 8662785
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket.
    Morishima Y; Murphy PJ; Li DP; Sanchez ER; Pratt WB
    J Biol Chem; 2000 Jun; 275(24):18054-60. PubMed ID: 10764743
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Animal and plant cell lysates share a conserved chaperone system that assembles the glucocorticoid receptor into a functional heterocomplex with hsp90.
    Stancato LF; Hutchison KA; Krishna P; Pratt WB
    Biochemistry; 1996 Jan; 35(2):554-61. PubMed ID: 8555227
    [TBL] [Abstract][Full Text] [Related]  

  • 7. hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1.
    Kanelakis KC; Murphy PJ; Galigniana MD; Morishima Y; Takayama S; Reed JC; Toft DO; Pratt WB
    Biochemistry; 2000 Nov; 39(46):14314-21. PubMed ID: 11087380
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.
    Hutchison KA; Dittmar KD; Stancato LF; Pratt WB
    J Steroid Biochem Mol Biol; 1996 Jun; 58(3):251-8. PubMed ID: 8836160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery.
    Kanelakis KC; Morishima Y; Dittmar KD; Galigniana MD; Takayama S; Reed JC; Pratt WB
    J Biol Chem; 1999 Nov; 274(48):34134-40. PubMed ID: 10567384
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.
    Hutchison KA; Stancato LF; Owens-Grillo JK; Johnson JL; Krishna P; Toft DO; Pratt WB
    J Biol Chem; 1995 Aug; 270(32):18841-7. PubMed ID: 7642537
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system.
    Morishima Y; Kanelakis KC; Silverstein AM; Dittmar KD; Estrada L; Pratt WB
    J Biol Chem; 2000 Mar; 275(10):6894-900. PubMed ID: 10702249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a "foldosome".
    Hutchison KA; Dittmar KD; Pratt WB
    J Biol Chem; 1994 Nov; 269(45):27894-9. PubMed ID: 7961721
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes.
    Morishima Y; Kanelakis KC; Murphy PJ; Shewach DS; Pratt WB
    Biochemistry; 2001 Jan; 40(4):1109-16. PubMed ID: 11170435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.
    Hutchison KA; Dittmar KD; Czar MJ; Pratt WB
    J Biol Chem; 1994 Feb; 269(7):5043-9. PubMed ID: 8106480
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor.
    Owens-Grillo JK; Hoffmann K; Hutchison KA; Yem AW; Deibel MR; Handschumacher RE; Pratt WB
    J Biol Chem; 1995 Sep; 270(35):20479-84. PubMed ID: 7657624
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly.
    Kanelakis KC; Shewach DS; Pratt WB
    J Biol Chem; 2002 Sep; 277(37):33698-703. PubMed ID: 12093808
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies with Purified Chaperones Advance the Understanding of the Mechanism of Glucocorticoid Receptor-hsp90 Heterocomplex Assembly.
    Pratt WB; Dittmar KD
    Trends Endocrinol Metab; 1998 Aug; 9(6):244-52. PubMed ID: 18406276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex.
    Czar MJ; Owens-Grillo JK; Dittmar KD; Hutchison KA; Zacharek AM; Leach KL; Deibel MR; Pratt WB
    J Biol Chem; 1994 Apr; 269(15):11155-61. PubMed ID: 8157642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-molecular-weight FK506-binding proteins are components of heat-shock protein 90 heterocomplexes in wheat germ lysate.
    Reddy RK; Kurek I; Silverstein AM; Chinkers M; Breiman A; Krishna P
    Plant Physiol; 1998 Dec; 118(4):1395-401. PubMed ID: 9847114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical reconstitution of steroid receptor•Hsp90 protein complexes and reactivation of ligand binding.
    Murphy PJ; Franklin HR; Furukawa NW
    J Vis Exp; 2011 Sep; (55):. PubMed ID: 21968922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.