These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 9516941)

  • 1. High susceptibility of human cancer xenografts with higher levels of cytidine deaminase to a 2'-deoxycytidine antimetabolite, 2'-deoxy-2'-methylidenecytidine.
    Miwa M; Eda H; Ura M; Ouchi KF; Keith DD; Foley LH; Ishitsuka H
    Clin Cancer Res; 1998 Feb; 4(2):493-7. PubMed ID: 9516941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase.
    Eda H; Ura M; F-Ouchi K; Tanaka Y; Miwa M; Ishitsuka H
    Cancer Res; 1998 Mar; 58(6):1165-9. PubMed ID: 9515801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo antitumor activity of a novel nucleoside, 4'-thio-2'-deoxy-2'-methylidenecytidine.
    Miura S; Tanaka M; Yoshimura Y; Satoh H; Sakata S; Machida H; Matsuda A; Sasaki T
    Biol Pharm Bull; 1996 Oct; 19(10):1311-5. PubMed ID: 8913503
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of differentiation of acute promyelocytic leukemia cells by a cytidine deaminase-resistant analogue of 1-beta-D-arabinofuranosylcytosine, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytidine.
    Niitsu N; Ishii Y; Matsuda A; Honma Y
    Cancer Res; 2001 Jan; 61(1):178-85. PubMed ID: 11196157
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The relationship between the antitumor activity and the ribonucleotide reductase inhibitory activity of (E)-2'-deoxy-2'-(fluoromethylene) cytidine, MDL 101,731.
    Kanazawa J; Takahashi T; Akinaga S; Tamaoki T; Okabe M
    Anticancer Drugs; 1998 Aug; 9(7):653-7. PubMed ID: 9773810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of cytidine deaminase on antitumor activity of 2'-deoxycytidine analogs in vitro and in vivo.
    Yoshida T; Endo Y; Obata T; Kosugi Y; Sakamoto K; Sasaki T
    Drug Metab Dispos; 2010 Oct; 38(10):1814-9. PubMed ID: 20587622
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
    Bergman AM; Adema AD; Balzarini J; Bruheim S; Fichtner I; Noordhuis P; Fodstad O; Myhren F; Sandvold ML; Hendriks HR; Peters GJ
    Invest New Drugs; 2011 Jun; 29(3):456-66. PubMed ID: 20066470
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The molecular targets of antitumor 2'-deoxycytidine analogues.
    Obata T; Endo Y; Murata D; Sakamoto K; Sasaki T
    Curr Drug Targets; 2003 May; 4(4):305-13. PubMed ID: 12699351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antitumor activity of 2'-deoxy-2'-methylidenecytidine, a new 2'-deoxycytidine derivative.
    Yamagami K; Fujii A; Arita M; Okumoto T; Sakata S; Matsuda A; Ueda T; Sasaki T
    Cancer Res; 1991 May; 51(9):2319-23. PubMed ID: 2015596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Use of 5-trifluoromethyldeoxycytidine and tetrahydrouridine to circumvent catabolism and exploit high levels of cytidine deaminase in tumors to achieve DNA- and target-directed therapies.
    Mekras JA; Boothman DA; Greer SB
    Cancer Res; 1985 Nov; 45(11 Pt 1):5270-80. PubMed ID: 2932216
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deletion mutants of human deoxycytidine kinase mRNA in cells resistant to antitumor cytosine nucleosides.
    Obata T; Endo Y; Tanaka M; Uchida H; Matsuda A; Sasaki T
    Jpn J Cancer Res; 2001 Jul; 92(7):793-8. PubMed ID: 11473731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity.
    Kroep JR; Loves WJ; van der Wilt CL; Alvarez E; Talianidis I; Boven E; Braakhuis BJ; van Groeningen CJ; Pinedo HM; Peters GJ
    Mol Cancer Ther; 2002 Apr; 1(6):371-6. PubMed ID: 12477049
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decreased resistance to gemcitabine (2',2'-difluorodeoxycitidine) of cytosine arabinoside-resistant myeloblastic murine and rat leukemia cell lines: role of altered activity and substrate specificity of deoxycytidine kinase.
    Bergman AM; Pinedo HM; Jongsma AP; Brouwer M; Ruiz van Haperen VW; Veerman G; Leyva A; Eriksson S; Peters GJ
    Biochem Pharmacol; 1999 Feb; 57(4):397-406. PubMed ID: 9933028
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase.
    Weizman N; Krelin Y; Shabtay-Orbach A; Amit M; Binenbaum Y; Wong RJ; Gil Z
    Oncogene; 2014 Jul; 33(29):3812-9. PubMed ID: 23995783
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines.
    Bergman AM; Munch-Petersen B; Jensen PB; Sehested M; Veerman G; Voorn DA; Smid K; Pinedo HM; Peters GJ
    Biochem Pharmacol; 2001 Jun; 61(11):1401-8. PubMed ID: 11331076
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlation between cytidine deaminase genotype and gemcitabine deamination in blood samples.
    Giovannetti E; Laan AC; Vasile E; Tibaldi C; Nannizzi S; Ricciardi S; Falcone A; Danesi R; Peters GJ
    Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):720-5. PubMed ID: 18600531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
    Gourdeau H; Clarke ML; Ouellet F; Mowles D; Selner M; Richard A; Lee N; Mackey JR; Young JD; Jolivet J; Lafrenière RG; Cass CE
    Cancer Res; 2001 Oct; 61(19):7217-24. PubMed ID: 11585758
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Similar changes were induced by Cladribine and by gemcitabine, in the deoxypyrimidine salvage, during short-term treatments.
    Csapó Z; Keszler G; Sasvári-Székely M; Smid K; Noordhuis P; Peters GJ; Staub M
    Adv Exp Med Biol; 1998; 431():525-9. PubMed ID: 9598122
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Forced expression of cytidine deaminase confers sensitivity to capecitabine.
    Morita T; Matsuzaki A; Kurokawa S; Tokue A
    Oncology; 2003; 65(3):267-74. PubMed ID: 14657601
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic studies on 2',2'-difluorodeoxycytidine (Gemcitabine) with purified human deoxycytidine kinase and cytidine deaminase.
    Bouffard DY; Laliberté J; Momparler RL
    Biochem Pharmacol; 1993 May; 45(9):1857-61. PubMed ID: 8494545
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.