150 related articles for article (PubMed ID: 9523317)
1. Dihydroorotate dehydrogenase inhibitors: quantitative structure-activity relationship analysis.
Ren S; Wu SK; Lien EJ
Pharm Res; 1998 Feb; 15(2):286-95. PubMed ID: 9523317
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationship of quinoline carboxylic acids. A new class of inhibitors of dihydroorotate dehydrogenase.
Chen SF; Papp LM; Ardecky RJ; Rao GV; Hesson DP; Forbes M; Dexter DL
Biochem Pharmacol; 1990 Aug; 40(4):709-14. PubMed ID: 2386542
[TBL] [Abstract][Full Text] [Related]
3. Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives.
Knecht W; Löffler M
Biochem Pharmacol; 1998 Nov; 56(9):1259-64. PubMed ID: 9802339
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase.
Boa AN; Canavan SP; Hirst PR; Ramsey C; Stead AM; McConkey GA
Bioorg Med Chem; 2005 Mar; 13(6):1945-67. PubMed ID: 15727850
[TBL] [Abstract][Full Text] [Related]
5. 3D-QSAR studies on a series of dihydroorotate dehydrogenase inhibitors: analogues of the active metabolite of leflunomide.
Li SL; He MY; Du HG
Int J Mol Sci; 2011; 12(5):2982-93. PubMed ID: 21686163
[TBL] [Abstract][Full Text] [Related]
6. QSAR study on a series of aryl carboxylic acid amide derivatives as potential inhibitors of dihydroorotate dehydrogenase (DHODH).
Vyas VK; Ghate M
Med Chem; 2013 Mar; 9(2):222-39. PubMed ID: 22920152
[TBL] [Abstract][Full Text] [Related]
7. Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid.
Knecht W; Henseling J; Löffler M
Chem Biol Interact; 2000 Jan; 124(1):61-76. PubMed ID: 10658902
[TBL] [Abstract][Full Text] [Related]
8. A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
DeRatt LG; Christine Pietsch E; Tanner A; Shaffer P; Jacoby E; Wang W; Kazmi F; Zhang X; Attar RM; Edwards JP; Kuduk SD
Bioorg Med Chem Lett; 2020 Nov; 30(22):127589. PubMed ID: 33007394
[TBL] [Abstract][Full Text] [Related]
9. Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase. A versatile tool to rate inhibitor effects?
Ullrich A; Knecht W; Fries M; Löffler M
Eur J Biochem; 2001 Mar; 268(6):1861-8. PubMed ID: 11248707
[TBL] [Abstract][Full Text] [Related]
10. Tetrahydro-1H,5H-pyrazolo[1,2-a]pyrazole-1-carboxylates as inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.
Strašek N; Lavrenčič L; Oštrek A; Slapšak D; Grošelj U; Klemenčič M; Brodnik Žugelj H; Wagger J; Novinec M; Svete J
Bioorg Chem; 2019 Aug; 89():102982. PubMed ID: 31132601
[TBL] [Abstract][Full Text] [Related]
11. Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies.
Petrović MM; Roschger C; Chaudary S; Zierer A; Mladenović M; Jakovljević K; Marković V; Botta B; Joksović MD
Bioorg Chem; 2020 Dec; 105():104373. PubMed ID: 33074120
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium.
Chen SF; Perrella FW; Behrens DL; Papp LM
Cancer Res; 1992 Jul; 52(13):3521-7. PubMed ID: 1617622
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of beta-hydroxy-propenamide derivatives and the inhibition of human dihydroorotate dehydrogenase.
Kim TH; Na HS; Löffler M
Arch Pharm Res; 2003 Mar; 26(3):197-201. PubMed ID: 12723931
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, structure-activity relationships, and pharmacokinetic properties of dihydroorotate dehydrogenase inhibitors: 2-cyano-3-cyclopropyl-3-hydroxy-N-[3'-methyl-4'-(trifluoromethyl)phenyl ] propenamide and related compounds.
Kuo EA; Hambleton PT; Kay DP; Evans PL; Matharu SS; Little E; McDowall N; Jones CB; Hedgecock CJ; Yea CM; Chan AW; Hairsine PW; Ager IR; Tully WR; Williamson RA; Westwood R
J Med Chem; 1996 Nov; 39(23):4608-21. PubMed ID: 8917650
[TBL] [Abstract][Full Text] [Related]
15. Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking.
Ren X; Liu X; Hua M; Dai Y; Ren X; Sui C; Li X; Jiang Z; Tian M; Yang B
Chem Biol Drug Des; 2024 Jan; 103(1):e14388. PubMed ID: 37926553
[TBL] [Abstract][Full Text] [Related]
16. Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase.
Madak JT; Cuthbertson CR; Miyata Y; Tamura S; Petrunak EM; Stuckey JA; Han Y; He M; Sun D; Showalter HD; Neamati N
J Med Chem; 2018 Jun; 61(12):5162-5186. PubMed ID: 29727569
[TBL] [Abstract][Full Text] [Related]
17. Novel Diketopiperazine Dihydroorotate Dehydrogenase Inhibitors Purified from Traditional Tibetan Animal Medicine Osteon Myospalacem Baileyi.
Jiang L; Wen H; Shao Y; Yu R; Liu Z; Wang S; Wang Q; Zhao X; Zhang P; Tao Y; Mei L
Chem Biol Drug Des; 2015 Oct; 86(4):626-36. PubMed ID: 25626527
[TBL] [Abstract][Full Text] [Related]
18. Biphenyl-4-ylcarbamoyl thiophene carboxylic acids as potent DHODH inhibitors.
Leban J; Kralik M; Mies J; Baumgartner R; Gassen M; Tasler S
Bioorg Med Chem Lett; 2006 Jan; 16(2):267-70. PubMed ID: 16246558
[TBL] [Abstract][Full Text] [Related]
19. Structural Optimization and Structure-Activity Relationship of 4-Thiazolidinone Derivatives as Novel Inhibitors of Human Dihydroorotate Dehydrogenase.
Zeng F; Quan L; Yang G; Qi T; Zhang L; Li S; Li H; Zhu L; Xu X
Molecules; 2019 Jul; 24(15):. PubMed ID: 31370178
[TBL] [Abstract][Full Text] [Related]
20. Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria.
Hoelz LV; Calil FA; Nonato MC; Pinheiro LC; Boechat N
Future Med Chem; 2018 Aug; 10(15):1853-1874. PubMed ID: 30019917
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
