BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 9525913)

  • 1. Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in chinese hamster ovary cells.
    Assaraf YG; Babani S; Goldman ID
    J Biol Chem; 1998 Apr; 273(14):8106-11. PubMed ID: 9525913
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of folic acid exporter function with markedly augmented folate accumulation in lipophilic antifolate-resistant mammalian cells.
    Assaraf YG; Goldman ID
    J Biol Chem; 1997 Jul; 272(28):17460-6. PubMed ID: 9211890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration.
    Jansen G; Barr H; Kathmann I; Bunni MA; Priest DG; Noordhuis P; Peters GJ; Assaraf YG
    Mol Pharmacol; 1999 Apr; 55(4):761-9. PubMed ID: 10101035
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate.
    Stark M; Rothem L; Jansen G; Scheffer GL; Goldman ID; Assaraf YG
    Mol Pharmacol; 2003 Aug; 64(2):220-7. PubMed ID: 12869626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitory effects of prostaglandin A1 on membrane transport of folates mediated by both the reduced folate carrier and ATP-driven exporters.
    Assaraf YG; Sierra EE; Babani S; Goldman ID
    Biochem Pharmacol; 1999 Oct; 58(8):1321-7. PubMed ID: 10487535
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function.
    Sierra EE; Goldman ID
    Biochem Pharmacol; 1998 May; 55(9):1505-12. PubMed ID: 10076544
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
    Jansen G; Mauritz RM; Assaraf YG; Sprecher H; Drori S; Kathmann I; Westerhof GR; Priest DG; Bunni M; Pinedo HM; Schornagel JH; Peters GJ
    Adv Enzyme Regul; 1997; 37():59-76. PubMed ID: 9381986
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.
    Jansen G; Mauritz R; Drori S; Sprecher H; Kathmann I; Bunni M; Priest DG; Noordhuis P; Schornagel JH; Pinedo HM; Peters GJ; Assaraf YG
    J Biol Chem; 1998 Nov; 273(46):30189-98. PubMed ID: 9804775
    [TBL] [Abstract][Full Text] [Related]  

  • 9. pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH.
    Sierra EE; Brigle KE; Spinella MJ; Goldman ID
    Biochem Pharmacol; 1997 Jan; 53(2):223-31. PubMed ID: 9037255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
    Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.
    Assaraf YG
    Drug Resist Updat; 2006; 9(4-5):227-46. PubMed ID: 17092765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier.
    Zhao R; Chattopadhyay S; Hanscom M; Goldman ID
    Clin Cancer Res; 2004 Dec; 10(24):8735-42. PubMed ID: 15623659
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells.
    Zhao R; Hanscom M; Goldman ID
    Biochim Biophys Acta; 2005 Aug; 1715(1):57-64. PubMed ID: 16109384
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.
    Zhao R; Assaraf YG; Goldman ID
    J Biol Chem; 1998 Jul; 273(30):19065-71. PubMed ID: 9668089
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates.
    Jansen G; Westerhof GR; Jarmuszewski MJ; Kathmann I; Rijksen G; Schornagel JH
    J Biol Chem; 1990 Oct; 265(30):18272-7. PubMed ID: 2211701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line.
    Dixon KH; Trepel JB; Eng SC; Cowan KH
    Cancer Commun; 1991; 3(12):357-65. PubMed ID: 16296001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methotrexate influx via folate transporters into alveolar epithelial cell line A549.
    Kawami M; Miyamoto M; Yumoto R; Takano M
    Drug Metab Pharmacokinet; 2015 Aug; 30(4):276-81. PubMed ID: 26190800
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells.
    Spinella MJ; Brigle KE; Sierra EE; Goldman ID
    J Biol Chem; 1995 Apr; 270(14):7842-9. PubMed ID: 7713875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 5,10-Dideazatetrahydrofolic acid (DDATHF) transport in CCRF-CEM and MA104 cell lines.
    Pizzorno G; Cashmore AR; Moroson BA; Cross AD; Smith AK; Marling-Cason M; Kamen BA; Beardsley GP
    J Biol Chem; 1993 Jan; 268(2):1017-23. PubMed ID: 8419310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier.
    Wang Y; Zhao R; Goldman ID
    Clin Cancer Res; 2004 Sep; 10(18 Pt 1):6256-64. PubMed ID: 15448015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.