249 related articles for article (PubMed ID: 9526569)
1. Design, synthesis, derivatization, and structure-activity relationships of simplified, tricyclic, 1,2,4-trioxane alcohol analogues of the antimalarial artemisinin.
Cumming JN; Wang D; Park SB; Shapiro TA; Posner GH
J Med Chem; 1998 Mar; 41(6):952-64. PubMed ID: 9526569
[TBL] [Abstract][Full Text] [Related]
2. Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.
O'Neill PM; Rawe SL; Borstnik K; Miller A; Ward SA; Bray PG; Davies J; Oh CH; Posner GH
Chembiochem; 2005 Nov; 6(11):2048-54. PubMed ID: 16222725
[TBL] [Abstract][Full Text] [Related]
3. Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity.
Posner GH; Oh CH; Wang D; Gerena L; Milhous WK; Meshnick SR; Asawamahasadka W
J Med Chem; 1994 Apr; 37(9):1256-8. PubMed ID: 8176702
[No Abstract] [Full Text] [Related]
4. Structure-activity relationships of lactone ring-opened analogs of the antimalarial 1,2,4-trioxane artemisinin.
Posner GH; McGarvey DJ; Oh CH; Kumar N; Meshnick SR; Asawamahasadka W
J Med Chem; 1995 Feb; 38(4):607-12. PubMed ID: 7861408
[TBL] [Abstract][Full Text] [Related]
5. Antimalarial cyclic peroxy ketals.
Posner GH; O'Dowd H; Ploypradith P; Cumming JN; Xie S; Shapiro TA
J Med Chem; 1998 Jun; 41(12):2164-7. PubMed ID: 9622557
[TBL] [Abstract][Full Text] [Related]
6. Design, Synthesis, and Biological Evaluation of Novel 1,2,4-Trioxanes as Potential Antimalarial Agents.
Gupta AK; Varshney K; Kumar V; Srivastava K; Pant AB; Puri SK; Saxena AK
Arch Pharm (Weinheim); 2017 Apr; 350(3-4):. PubMed ID: 28207169
[TBL] [Abstract][Full Text] [Related]
7. Alkylation of manganese(II) tetraphenylporphyrin by a synthetic antimalarial trioxane.
Berrien JF; Provot O; Mayrargue J; Coquillay M; Cicéron L; Gay F; Danis M; Robert A; Meunier B
Org Biomol Chem; 2003 Aug; 1(16):2859-64. PubMed ID: 12968336
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and antimalarial activity of some 9-substituted artemisinin derivatives.
Acton N; Karle JM; Miller RE
J Med Chem; 1993 Aug; 36(17):2552-7. PubMed ID: 8355254
[TBL] [Abstract][Full Text] [Related]
9. [Recent advances in the study of artemisinin-related 1,2,4-trioxanes and ozonides (1,2,4-trioxolanes) as antimalarials].
Yang ZS; Li Y
Yao Xue Xue Bao; 2005 Dec; 40(12):1057-63. PubMed ID: 16496665
[No Abstract] [Full Text] [Related]
10. Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates.
Avery MA; Alvim-Gaston M; Vroman JA; Wu B; Ager A; Peters W; Robinson BL; Charman W
J Med Chem; 2002 Sep; 45(19):4321-35. PubMed ID: 12213073
[TBL] [Abstract][Full Text] [Related]
11. Conversion of antimalarial drug artemisinin to a new series of tricyclic 1,2,4-trioxanes1.
Singh C; Chaudhary S; Kanchan R; Puri SK
Org Lett; 2007 Oct; 9(21):4327-9. PubMed ID: 17877363
[TBL] [Abstract][Full Text] [Related]
12. Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of benzylamino and alkylamino ether analogues of artemisinin.
O'Neill PM; Bishop LP; Storr RC; Hawley SR; Maggs JL; Ward SA; Park BK
J Med Chem; 1996 Oct; 39(22):4511-4. PubMed ID: 8893847
[TBL] [Abstract][Full Text] [Related]
13. Design, Synthesis, Structure-Activity Relationship and Docking Studies of Novel Functionalized Arylvinyl-1,2,4-Trioxanes as Potent Antiplasmodial as well as Anticancer Agents.
Tiwari MK; Coghi P; Agrawal P; Shyamlal BRK; Jun Yang L; Yadav L; Peng Y; Sharma R; Yadav DK; Sahal D; Kam Wai Wong V; Chaudhary S
ChemMedChem; 2020 Jul; 15(13):1216-1228. PubMed ID: 32392362
[TBL] [Abstract][Full Text] [Related]
14. Novel halogenated arylvinyl-1,2,4 trioxanes as potent antiplasmodial as well as anticancer agents: Synthesis, bioevaluation, structure-activity relationship and in-silico studies.
Tiwari MK; Coghi P; Agrawal P; Yadav DK; Yang LJ; Congling Q; Sahal D; Wai Wong VK; Chaudhary S
Eur J Med Chem; 2021 Nov; 224():113685. PubMed ID: 34303874
[TBL] [Abstract][Full Text] [Related]
15. A QSAR study of the antimalarial activity of some synthetic 1,2,4-trioxanes.
Grigorov M; Weber J; Tronchet JM; Jefford CW; Milhous WK; Maric D
J Chem Inf Comput Sci; 1997; 37(1):124-30. PubMed ID: 9025258
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of new artemisinin analogues from artemisinic acid modified at C-3 and C-13 and their antimalarial activity.
Han J; Lee JG; Min SS; Park SH; Angerhofer CK; Cordell GA; Kim SU
J Nat Prod; 2001 Sep; 64(9):1201-5. PubMed ID: 11575956
[TBL] [Abstract][Full Text] [Related]
17. Endoperoxide antimalarials: development, structural diversity and pharmacodynamic aspects with reference to 1,2,4-trioxane-based structural scaffold.
Rudrapal M; Chetia D
Drug Des Devel Ther; 2016; 10():3575-3590. PubMed ID: 27843298
[TBL] [Abstract][Full Text] [Related]
18. Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
Avery MA; Muraleedharan KM; Desai PV; Bandyopadhyaya AK; Furtado MM; Tekwani BL
J Med Chem; 2003 Sep; 46(20):4244-58. PubMed ID: 13678403
[TBL] [Abstract][Full Text] [Related]
19. Trioxaferroquines as new hybrid antimalarial drugs.
Bellot F; Coslédan F; Vendier L; Brocard J; Meunier B; Robert A
J Med Chem; 2010 May; 53(10):4103-9. PubMed ID: 20443628
[TBL] [Abstract][Full Text] [Related]
20. Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether.
O'Neill PM; Searle NL; Kan KW; Storr RC; Maggs JL; Ward SA; Raynes K; Park BK
J Med Chem; 1999 Dec; 42(26):5487-93. PubMed ID: 10639291
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
