These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 9526571)

  • 1. Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.
    Rosenblum SB; Huynh T; Afonso A; Davis HR; Yumibe N; Clader JW; Burnett DA
    J Med Chem; 1998 Mar; 41(6):973-80. PubMed ID: 9526571
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus.
    Clader JW; Burnett DA; Caplen MA; Domalski MS; Dugar S; Vaccaro W; Sher R; Browne ME; Zhao H; Burrier RE; Salisbury B; Davis HR
    J Med Chem; 1996 Sep; 39(19):3684-93. PubMed ID: 8809157
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats.
    van Heek M; Farley C; Compton DS; Hoos LM; Smith-Torhan A; Davis HR
    Br J Pharmacol; 2003 Apr; 138(8):1459-64. PubMed ID: 12721101
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
    Ghosal A; Hapangama N; Yuan Y; Achanfuo-Yeboah J; Iannucci R; Chowdhury S; Alton K; Patrick JE; Zbaida S
    Drug Metab Dispos; 2004 Mar; 32(3):314-20. PubMed ID: 14977865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461.
    Salisbury BG; Davis HR; Burrier RE; Burnett DA; Bowkow G; Caplen MA; Clemmons AL; Compton DS; Hoos LM; McGregor DG
    Atherosclerosis; 1995 May; 115(1):45-63. PubMed ID: 7669087
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sugar-substituted 2-azetidinone cholesterol absorption inhibitors: enhanced potency by modification of the sugar.
    Vaccaro WD; Davis HR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):313-8. PubMed ID: 9871676
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Azetidinone cholesterol absorption inhibitors: increased potency by substitution of the C-4 phenyl ring.
    Vaccaro WD; Sher R; Davis HR
    Bioorg Med Chem; 1998 Sep; 6(9):1429-37. PubMed ID: 9801814
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461.
    Van Heek M; France CF; Compton DS; McLeod RL; Yumibe NP; Alton KB; Sybertz EJ; Davis HR
    J Pharmacol Exp Ther; 1997 Oct; 283(1):157-63. PubMed ID: 9336320
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carboxy-substituted 2-azetidinones as cholesterol absorption inhibitors.
    Vaccaro WD; Sher R; Davis HR
    Bioorg Med Chem Lett; 1998 Feb; 8(3):319-22. PubMed ID: 9871677
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.
    Davis HR; Pula KK; Alton KB; Burrier RE; Watkins RW
    Metabolism; 2001 Oct; 50(10):1234-41. PubMed ID: 11586500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of iodinated biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
    Burnett DA; Caplen MA; Domalski MS; Browne ME; Davis HR; Clader JW
    Bioorg Med Chem Lett; 2002 Feb; 12(3):311-4. PubMed ID: 11814785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2-Azetidinone derivatives: design, synthesis and evaluation of cholesterol absorption inhibitors.
    Wang Y; Zhang H; Huang W; Kong J; Zhou J; Zhang B
    Eur J Med Chem; 2009 Apr; 44(4):1638-43. PubMed ID: 18990470
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions.
    Xu X; Fu R; Chen J; Chen S; Bai X
    Bioorg Med Chem Lett; 2007 Jan; 17(1):101-4. PubMed ID: 17049851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of fluorescent biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
    Burnett DA; Caplen MA; Browne ME; Zhau H; Altmann SW; Davis HR; Clader JW
    Bioorg Med Chem Lett; 2002 Feb; 12(3):315-8. PubMed ID: 11814786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys.
    van Heek M; Compton DS; Davis HR
    Eur J Pharmacol; 2001 Mar; 415(1):79-84. PubMed ID: 11245855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity.
    McKittrick BA; Ma K; Huie K; Yumibe N; Davis H; Clader JW; Czarniecki M; McPhail AT
    J Med Chem; 1998 Feb; 41(5):752-9. PubMed ID: 9513603
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Steroidal glycoside cholesterol absorption inhibitors.
    DeNinno MP; McCarthy PA; Duplantier KC; Eller C; Etienne JB; Zawistoski MP; Bangerter FW; Chandler CE; Morehouse LA; Sugarman ED; Wilkins RW; Woody HA; Zaccaro LM
    J Med Chem; 1997 Aug; 40(16):2547-54. PubMed ID: 9258361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and in vitro evaluation of inhibitors of intestinal cholesterol absorption.
    Kvaernø L; Werder M; Hauser H; Carreira EM
    J Med Chem; 2005 Sep; 48(19):6035-53. PubMed ID: 16162006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A formal synthesis of ezetimibe via cycloaddition/rearrangement cascade reaction.
    Michalak M; Stodulski M; Stecko S; Mames A; Panfil I; Soluch M; Furman B; Chmielewski M
    J Org Chem; 2011 Aug; 76(16):6931-6. PubMed ID: 21744801
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sugar-substituted 2-azetidinones as cholesterol absorption inhibitors.
    Vaccaro WD; Sher R; Davis HR
    Bioorg Med Chem Lett; 1998 Jan; 8(1):35-40. PubMed ID: 9871624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.