These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 9540103)

  • 1. Antitumour drug design: DNA-binding ligands, which inhibit the topoisomerase I.
    Pindur U; Lemster T
    Pharmazie; 1998 Feb; 53(2):79-86. PubMed ID: 9540103
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities.
    Bailly C; Qu X; Chaires JB; Colson P; Houssier C; Ohkubo M; Nishimura S; Yoshinari T
    J Med Chem; 1999 Jul; 42(15):2927-35. PubMed ID: 10425102
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.
    Cho HJ; Jung MJ; Kwon Y; Na Y
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6766-9. PubMed ID: 19836231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model.
    Zeng Q; Kwok Y; Kerwin SM; Mangold G; Hurley LH
    J Med Chem; 1998 Oct; 41(22):4273-8. PubMed ID: 9784102
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S; Vandenberghe I; Robin M; Annereau JP; Créancier L; Pique V; Galy JP; Kruczynski A; Barret JM; Bailly C
    Biochem Pharmacol; 2007 Jun; 73(12):1863-72. PubMed ID: 17391647
    [TBL] [Abstract][Full Text] [Related]  

  • 7. L-proline analogues of anthraquinone-2-carboxylic acid: cytotoxic activity in breast cancer MCF-7 cells and inhibitory activity against topoisomerase I and II.
    Bielawska A; Kosk K; Bielawski K
    Pol J Pharmacol; 2001; 53(3):283-7. PubMed ID: 11785929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Topoisomerases I: new targets for the treatment of cancer and mechanisms of resistance].
    Pourquier P; Pommier Y
    Bull Cancer; 1998 Dec; Spec No():5-10. PubMed ID: 9932078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of a series of fluoroquinoanthroxazines with contrasting dual mechanisms of action against topoisomerase II and G-quadruplexes.
    Kim MY; Duan W; Gleason-Guzman M; Hurley LH
    J Med Chem; 2003 Feb; 46(4):571-83. PubMed ID: 12570378
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Emerging DNA topisomerase inhibitors as anticancer drugs.
    Denny WA
    Expert Opin Emerg Drugs; 2004 May; 9(1):105-33. PubMed ID: 15155139
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, mode of action, and biological activities of rebeccamycin bromo derivatives.
    Moreau P; Anizon F; Sancelme M; Prudhomme M; Sevère D; Riou JF; Goossens JF; Hénichart JP; Bailly C; Labourier E; Tazzi J; Fabbro D; Meyer T; Aubertin AM
    J Med Chem; 1999 May; 42(10):1816-22. PubMed ID: 10346933
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA topoisomerases in cancer chemotherapy: using enzymes to generate selective DNA damage.
    Nitiss JL
    Curr Opin Investig Drugs; 2002 Oct; 3(10):1512-6. PubMed ID: 12431029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.
    Morrell A; Antony S; Kohlhagen G; Pommier Y; Cushman M
    Bioorg Med Chem Lett; 2004 Jul; 14(14):3659-63. PubMed ID: 15203138
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel camptothecin derivatives as topoisomerase I inhibitors.
    Basili S; Moro S
    Expert Opin Ther Pat; 2009 May; 19(5):555-74. PubMed ID: 19441934
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel autoxidative cleavage reaction of 9-fluoredenes discovered during synthesis of a potential DNA-threading indenoisoquinoline.
    Xiao X; Antony S; Kohlhagen G; Pommier Y; Cushman M
    J Org Chem; 2004 Oct; 69(22):7495-501. PubMed ID: 15497974
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Understanding topoisomerase I and II in terms of QSAR.
    Verma RP
    Bioorg Med Chem; 2005 Feb; 13(4):1059-67. PubMed ID: 15670914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor polycyclic acridines. Part 12. Physical and biological properties of 8,13-diethyl-6-methylquino[4,3,2-kl]acridinium iodide: a lead compound in anticancer drug design.
    Missailidis S; Stanslas J; Modi C; Ellis MJ; Robins RA; Laughton CA; Stevens MF
    Oncol Res; 2002; 13(3):175-89. PubMed ID: 12549627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin.
    Fan Y; Weinstein JN; Kohn KW; Shi LM; Pommier Y
    J Med Chem; 1998 Jun; 41(13):2216-26. PubMed ID: 9632354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2,4,6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Basnet A; Thapa P; Karki R; Na Y; Jahng Y; Jeong BS; Jeong TC; Lee CS; Lee ES
    Bioorg Med Chem; 2007 Jul; 15(13):4351-9. PubMed ID: 17493824
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oligopyrrole carboxamides linked with a nucleobase as potential DNA minor groove binding ligands: synthesis, DNA binding and biological evaluation.
    Keuser C; Pindur U
    Pharmazie; 2006 Apr; 61(4):261-8. PubMed ID: 16649534
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.