BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 9548535)

  • 1. Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: a novel agent for the elimination of IL-7 receptor positive cells.
    Sweeney EB; Foss FM; Murphy JR; vanderSpek JC
    Bioconjug Chem; 1998; 9(2):201-7. PubMed ID: 9548535
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interleukin 4 receptor targeted cytotoxicity: genetic construction and in vivo immunosuppressive activity of a diphtheria toxin-related murine interleukin 4 fusion protein.
    Lakkis F; Steele A; Pacheco-Silva A; Rubin-Kelley V; Strom TB; Murphy JR
    Eur J Immunol; 1991 Sep; 21(9):2253-8. PubMed ID: 1679715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of protein synthesis in small cell lung cancer cells induced by the diphtheria toxin-related fusion protein DAB389 GRP.
    vanderSpek JC; Sutherland JA; Zeng H; Battey JF; Jensen RT; Murphy JR
    Cancer Res; 1997 Jan; 57(2):290-4. PubMed ID: 9000570
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential sensitivity of human myeloma cell lines and normal bone marrow colony forming cells to a recombinant diphtheria toxin-interleukin 6 fusion protein.
    Chadwick DE; Jean LF; Jamal N; Messner HA; Murphy JR; Minden MD
    Br J Haematol; 1993 Sep; 85(1):25-36. PubMed ID: 8251407
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diphtheria toxin-based receptor-specific chimaeric toxins as targeted therapies.
    Sweeney EB; Murphy JR
    Essays Biochem; 1995; 30():119-31. PubMed ID: 8822152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.
    Liu TF; Urieto JO; Moore JE; Miller MS; Lowe AC; Thorburn A; Frankel AE
    Exp Hematol; 2004 Mar; 32(3):277-81. PubMed ID: 15003313
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interleukin 2 receptor-targeted cytotoxicity. Receptor binding requirements for entry of a diphtheria toxin-related interleukin 2 fusion protein into cells.
    Waters CA; Schimke PA; Snider CE; Itoh K; Smith KA; Nichols JC; Strom TB; Murphy JR
    Eur J Immunol; 1990 Apr; 20(4):785-91. PubMed ID: 2140788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytotoxicity of interleukin 2-toxin toward lymphocytes from patients with adult T-cell leukemia.
    Kiyokawa T; Shirono K; Hattori T; Nishimura H; Yamaguchi K; Nichols JC; Strom TB; Murphy JR; Takatsuki K
    Cancer Res; 1989 Jul; 49(14):4042-6. PubMed ID: 2786749
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
    Feuring-Buske M; Frankel AE; Alexander RL; Gerhard B; Hogge DE
    Cancer Res; 2002 Mar; 62(6):1730-6. PubMed ID: 11912147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic construction and characterization of the diphtheria toxin-related interleukin 15 fusion protein DAB389 sIL-15.
    vanderSpek JC; Sutherland J; Sampson E; Murphy JR
    Protein Eng; 1995 Dec; 8(12):1317-21. PubMed ID: 8869645
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene.
    Vallera DA; Jin N; Baldrica JM; Panoskaltsis-Mortari A; Chen SY; Blazar BR
    Cancer Res; 2000 Feb; 60(4):976-84. PubMed ID: 10706113
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Production of recombinant DTctGMCSF fusion toxin in a baculovirus expression vector system for biotherapy of GMCSF-receptor positive hematologic malignancies.
    Williams MD; Rostovtsev A; Narla RK; Uckun FM
    Protein Expr Purif; 1998 Jul; 13(2):210-21. PubMed ID: 9675065
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Diphtheria toxin receptor-binding domain substitution with interleukin 6: genetic construction and interleukin 6 receptor-specific action of a diphtheria toxin-related interleukin 6 fusion protein.
    Jean LF; Murphy JR
    Protein Eng; 1991 Dec; 4(8):989-94. PubMed ID: 1817263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
    vanderSpek JC; Mindell JA; Finkelstein A; Murphy JR
    J Biol Chem; 1993 Jun; 268(16):12077-82. PubMed ID: 8505330
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia.
    Barata JT; Keenan TD; Silva A; Nadler LM; Boussiotis VA; Cardoso AA
    Haematologica; 2004 Dec; 89(12):1459-67. PubMed ID: 15590396
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma.
    Vallera DA; Todhunter DA; Kuroki DW; Shu Y; Sicheneder A; Chen H
    Clin Cancer Res; 2005 May; 11(10):3879-88. PubMed ID: 15897589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A single-chain IL-12 IgG3 antibody fusion protein retains antibody specificity and IL-12 bioactivity and demonstrates antitumor activity.
    Peng LS; Penichet ML; Morrison SL
    J Immunol; 1999 Jul; 163(1):250-8. PubMed ID: 10384123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IL-2Ralpha-Directed monoclonal antibodies provide effective therapy in a murine model of adult T-cell leukemia by a mechanism other than blockade of IL-2/IL-2Ralpha interaction.
    Phillips KE; Herring B; Wilson LA; Rickford MS; Zhang M; Goldman CK; Tso JY; Waldmann TA
    Cancer Res; 2000 Dec; 60(24):6977-84. PubMed ID: 11156399
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways.
    Kim K; Lee CK; Sayers TJ; Muegge K; Durum SK
    J Immunol; 1998 Jun; 160(12):5735-41. PubMed ID: 9637482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
    Urieto JO; Liu T; Black JH; Cohen KA; Hall PD; Willingham MC; Pennell LK; Hogge DE; Kreitman RJ; Frankel AE
    Protein Expr Purif; 2004 Jan; 33(1):123-33. PubMed ID: 14680969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.