BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 9548959)

  • 21. Binding, partial agonism, and potentiation of alpha(1)-adrenergic receptor function by benzodiazepines: A potential site of allosteric modulation.
    Waugh DJ; Gaivin RJ; Damron DS; Murray PA; Perez DM
    J Pharmacol Exp Ther; 1999 Dec; 291(3):1164-71. PubMed ID: 10565838
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation.
    Scheer A; Costa T; Fanelli F; De Benedetti PG; Mhaouty-Kodja S; Abuin L; Nenniger-Tosato M; Cotecchia S
    Mol Pharmacol; 2000 Feb; 57(2):219-31. PubMed ID: 10648631
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Computational study of antagonist/alpha1A adrenoceptor complexes--observations of conformational variations on the formation of ligand/receptor complexes.
    Kinsella GK; Rozas I; Watson GW
    J Med Chem; 2006 Jan; 49(2):501-10. PubMed ID: 16420037
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of critical determinants of alpha 1-adrenergic receptor subtype selective agonist binding.
    Hwa J; Graham RM; Perez DM
    J Biol Chem; 1995 Sep; 270(39):23189-95. PubMed ID: 7559466
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Constitutive activity and inverse agonism at the alpha1adrenoceptors.
    Cotecchia S
    Biochem Pharmacol; 2007 Apr; 73(8):1076-83. PubMed ID: 17125741
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Prazosin-related compounds. Effect of transforming the piperazinylquinazoline moiety into an aminomethyltetrahydroacridine system on the affinity for alpha1-adrenoreceptors.
    Rosini M; Antonello A; Cavalli A; Bolognesi ML; Minarini A; Marucci G; Poggesi E; Leonardi A; Melchiorre C
    J Med Chem; 2003 Nov; 46(23):4895-903. PubMed ID: 14584940
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands.
    Li S; Chiu G; Pulito VL; Liu J; Connolly PJ; Middleton SA
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1646-50. PubMed ID: 17254786
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Binding sites and transduction process of the cholecystokininB receptor: involvement of highly conserved aromatic residues of the transmembrane domains evidenced by site-directed mutagenesis.
    Jagerschmidt A; Guillaume N; Roques BP; Noble F
    Mol Pharmacol; 1998 May; 53(5):878-85. PubMed ID: 9584214
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA; Doufexis M; Kapas S; Chhajlani V
    Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Truncated isoforms inhibit [3H]prazosin binding and cellular trafficking of native human alpha1A-adrenoceptors.
    Cogé F; Guenin SP; Renouard-Try A; Rique H; Ouvry C; Fabry N; Beauverger P; Nicolas JP; Galizzi JP; Boutin JA; Canet E
    Biochem J; 1999 Oct; 343 Pt 1(Pt 1):231-9. PubMed ID: 10493934
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states.
    Millan MJ; Newman-Tancredi A; Audinot V; Cussac D; Lejeune F; Nicolas JP; Cogé F; Galizzi JP; Boutin JA; Rivet JM; Dekeyne A; Gobert A
    Synapse; 2000 Feb; 35(2):79-95. PubMed ID: 10611634
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Binding site analysis of full-length alpha1a adrenergic receptor using homology modeling and molecular docking.
    Pedretti A; Elena Silva M; Villa L; Vistoli G
    Biochem Biophys Res Commun; 2004 Jun; 319(2):493-500. PubMed ID: 15178433
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Alpha 1-adrenoceptor subtype selectivity: molecular modelling and theoretical quantitative structure-affinity relationships.
    De Benedetti PG; Fanelli F; Menziani MC; Cocchi M; Testa R; Leonardi A
    Bioorg Med Chem; 1997 May; 5(5):809-16. PubMed ID: 9208092
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Frontal analysis of cell-membrane chromatography for determination of drug-alpha(1D) adrenergic receptor affinity.
    Zeng A; Yuan B; Wang C; Yang G; He L
    J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Jul; 877(20-21):1833-7. PubMed ID: 19493707
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mutational analysis of the alpha 1a-adrenergic receptor binding pocket of antagonists by radioligand binding assay.
    Ahmed M; Hossain M; Bhuiyan MA; Ishiguro M; Tanaka T; Muramatsu I; Nagatomo T
    Biol Pharm Bull; 2008 Apr; 31(4):598-601. PubMed ID: 18379048
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety.
    Murali Dhar TG; Nagarathnam D; Marzabadi MR; Lagu B; Wong WC; Chiu G; Tyagarajan S; Miao SW; Zhang F; Sun W; Tian D; Shen Q; Zhang J; Wetzel JM; Forray C; Chang RS; Broten TP; Schorn TW; Chen TB; O'Malley S; Ransom R; Schneck K; Bendesky R; Harrell CM; Vyas KP
    J Med Chem; 1999 Nov; 42(23):4778-93. PubMed ID: 10579841
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha 1d adrenergic receptor.
    Leonardi A; Barlocco D; Montesano F; Cignarella G; Motta G; Testa R; Poggesi E; Seeber M; De Benedetti PG; Fanelli F
    J Med Chem; 2004 Apr; 47(8):1900-18. PubMed ID: 15055991
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel aromatic residues in transmembrane domains IV and V involved in agonist binding at alpha(1a)-adrenergic receptors.
    Waugh DJ; Zhao MM; Zuscik MJ; Perez DM
    J Biol Chem; 2000 Apr; 275(16):11698-705. PubMed ID: 10766790
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Key amino acids located within the transmembrane domains 5 and 7 account for the pharmacological specificity of the human V1b vasopressin receptor.
    Derick S; Pena A; Durroux T; Wagnon J; Serradeil-Le Gal C; Hibert M; Rognan D; Guillon G
    Mol Endocrinol; 2004 Nov; 18(11):2777-89. PubMed ID: 15284336
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Modeling the interactions between alpha(1)-adrenergic receptors and their antagonists.
    Du L; Li M
    Curr Comput Aided Drug Des; 2010 Sep; 6(3):165-78. PubMed ID: 20412040
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.