These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction. Saharinen P; Silvennoinen O J Biol Chem; 2002 Dec; 277(49):47954-63. PubMed ID: 12351625 [TBL] [Abstract][Full Text] [Related]
3. Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Fernández L; Flores-Morales A; Lahuna O; Sliva D; Norstedt G; Haldosén LA; Mode A; Gustafsson JA Endocrinology; 1998 Apr; 139(4):1815-24. PubMed ID: 9528967 [TBL] [Abstract][Full Text] [Related]
4. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT. Fujitani Y; Hibi M; Fukada T; Takahashi-Tezuka M; Yoshida H; Yamaguchi T; Sugiyama K; Yamanaka Y; Nakajima K; Hirano T Oncogene; 1997 Feb; 14(7):751-61. PubMed ID: 9047382 [TBL] [Abstract][Full Text] [Related]
5. Platelet-derived growth factor (PDGF)-induced activation of signal transducer and activator of transcription (Stat) 5 is mediated by PDGF beta-receptor and is not dependent on c-src, fyn, jak1 or jak2 kinases. Paukku K; Valgeirsdóttir S; Saharinen P; Bergman M; Heldin CH; Silvennoinen O Biochem J; 2000 Feb; 345 Pt 3(Pt 3):759-66. PubMed ID: 10642538 [TBL] [Abstract][Full Text] [Related]
6. A new protein containing an SH2 domain that inhibits JAK kinases. Endo TA; Masuhara M; Yokouchi M; Suzuki R; Sakamoto H; Mitsui K; Matsumoto A; Tanimura S; Ohtsubo M; Misawa H; Miyazaki T; Leonor N; Taniguchi T; Fujita T; Kanakura Y; Komiya S; Yoshimura A Nature; 1997 Jun; 387(6636):921-4. PubMed ID: 9202126 [TBL] [Abstract][Full Text] [Related]
7. Regulation of the Jak2 tyrosine kinase by its pseudokinase domain. Saharinen P; Takaluoma K; Silvennoinen O Mol Cell Biol; 2000 May; 20(10):3387-95. PubMed ID: 10779328 [TBL] [Abstract][Full Text] [Related]
8. Dominant negative variants of the SHP-2 tyrosine phosphatase inhibit prolactin activation of Jak2 (janus kinase 2) and induction of Stat5 (signal transducer and activator of transcription 5)-dependent transcription. Berchtold S; Volarevic S; Moriggl R; Mercep M; Groner B Mol Endocrinol; 1998 Apr; 12(4):556-67. PubMed ID: 9544991 [TBL] [Abstract][Full Text] [Related]
9. Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway. Chin H; Arai A; Wakao H; Kamiyama R; Miyasaka N; Miura O Blood; 1998 May; 91(10):3734-45. PubMed ID: 9573010 [TBL] [Abstract][Full Text] [Related]
10. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH. Smit LS; Meyer DJ; Billestrup N; Norstedt G; Schwartz J; Carter-Su C Mol Endocrinol; 1996 May; 10(5):519-33. PubMed ID: 8732683 [TBL] [Abstract][Full Text] [Related]
11. An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells. Nakamura N; Chin H; Miyasaka N; Miura O J Biol Chem; 1996 Aug; 271(32):19483-8. PubMed ID: 8702638 [TBL] [Abstract][Full Text] [Related]
12. Prolactin receptor regulates Stat5 tyrosine phosphorylation and nuclear translocation by two separate pathways. Ali S; Ali S J Biol Chem; 1998 Mar; 273(13):7709-16. PubMed ID: 9516478 [TBL] [Abstract][Full Text] [Related]
13. Differential activation of Stat3 and Stat5 by distinct regions of the growth hormone receptor. Sotiropoulos A; Moutoussamy S; Renaudie F; Clauss M; Kayser C; Gouilleux F; Kelly PA; Finidori J Mol Endocrinol; 1996 Aug; 10(8):998-1009. PubMed ID: 8843416 [TBL] [Abstract][Full Text] [Related]
14. Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2. Rui L; Carter-Su C Proc Natl Acad Sci U S A; 1999 Jun; 96(13):7172-7. PubMed ID: 10377387 [TBL] [Abstract][Full Text] [Related]
15. Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase. Yi W; Kim SO; Jiang J; Park SH; Kraft AS; Waxman DJ; Frank SJ Mol Endocrinol; 1996 Nov; 10(11):1425-43. PubMed ID: 8923468 [TBL] [Abstract][Full Text] [Related]
16. Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway. Okutani Y; Kitanaka A; Tanaka T; Kamano H; Ohnishi H; Kubota Y; Ishida T; Takahara J Oncogene; 2001 Oct; 20(45):6643-50. PubMed ID: 11641791 [TBL] [Abstract][Full Text] [Related]
17. Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor. Le MN; Kohanski RA; Wang LH; Sadowski HB Mol Endocrinol; 2002 Dec; 16(12):2764-79. PubMed ID: 12456798 [TBL] [Abstract][Full Text] [Related]
18. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. Carlesso N; Frank DA; Griffin JD J Exp Med; 1996 Mar; 183(3):811-20. PubMed ID: 8642285 [TBL] [Abstract][Full Text] [Related]
19. Cytokine receptor-independent, constitutively active variants of STAT5. Berchtold S; Moriggl R; Gouilleux F; Silvennoinen O; Beisenherz C; Pfitzner E; Wissler M; Stöcklin E; Groner B J Biol Chem; 1997 Nov; 272(48):30237-43. PubMed ID: 9374508 [TBL] [Abstract][Full Text] [Related]