BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 9579383)

  • 1. Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease.
    Richardson DR; Ponka P
    J Lab Clin Med; 1998 Apr; 131(4):306-15. PubMed ID: 9579383
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate.
    Hermes-Lima M; Ponka P; Schulman HM
    Biochim Biophys Acta; 2000 Oct; 1523(2-3):154-60. PubMed ID: 11042379
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biliary iron excretion in rats following treatment with analogs of pyridoxal isonicotinoyl hydrazone.
    Bláha K; Cikrt M; Nerudová J; Ponka HF
    Blood; 1998 Jun; 91(11):4368-72. PubMed ID: 9596686
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analogues of pyridoxal isonicotinoyl hydrazone (PIH) as potential iron chelators for the treatment of neoplasia.
    Richardson DR
    Leuk Lymphoma; 1998 Sep; 31(1-2):47-60. PubMed ID: 9720714
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of novel aroylhydrazone ligands for iron chelation therapy: 2-pyridylcarboxaldehyde isonicotinoyl hydrazone analogs.
    Becker E; Richardson DR
    J Lab Clin Med; 1999 Nov; 134(5):510-21. PubMed ID: 10560945
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Orally effective iron chelators for the treatment of iron overload disease: the case for a further look at pyridoxal isonicotinoyl hydrazone and its analogs.
    Richardson DR; Ponka P
    J Lab Clin Med; 1998 Oct; 132(4):351-2. PubMed ID: 9794707
    [No Abstract]   [Full Text] [Related]  

  • 7. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents.
    Richardson DR; Tran EH; Ponka P
    Blood; 1995 Dec; 86(11):4295-306. PubMed ID: 7492790
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation.
    Darnell G; Richardson DR
    Blood; 1999 Jul; 94(2):781-92. PubMed ID: 10397746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells.
    Link G; Ponka P; Konijn AM; Breuer W; Cabantchik ZI; Hershko C
    Blood; 2003 May; 101(10):4172-9. PubMed ID: 12511418
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone.
    Richardson DR; Milnes K
    Blood; 1997 Apr; 89(8):3025-38. PubMed ID: 9108424
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs.
    Buss JL; Neuzil J; Ponka P
    Arch Biochem Biophys; 2004 Jan; 421(1):1-9. PubMed ID: 14678779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. EPR spin trapping and 2-deoxyribose degradation studies of the effect of pyridoxal isonicotinoyl hydrazone (PIH) on *OH formation by the Fenton reaction.
    Hermes-Lima M; Santos NC; Yan J; Andrews M; Schulman HM; Ponka P
    Biochim Biophys Acta; 1999 Feb; 1426(3):475-82. PubMed ID: 10076064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipophilicity of analogs of pyridoxal isonicotinoyl hydrazone (PIH) determines the efflux of iron complexes and toxicity in K562 cells.
    Buss JL; Arduini E; Shephard KC; Ponka P
    Biochem Pharmacol; 2003 Feb; 65(3):349-60. PubMed ID: 12527328
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes.
    Buss JL; Arduini E; Ponka P
    Biochem Pharmacol; 2002 Dec; 64(12):1689-701. PubMed ID: 12445858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydrolysis of pyridoxal isonicotinoyl hydrazone and its analogs.
    Buss JL; Ponka P
    Biochim Biophys Acta; 2003 Jan; 1619(2):177-86. PubMed ID: 12527114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyridoxal isonicotinoyl hydrazone (PIH) and its analogs as protectants against anthracycline-induced cardiotoxicity.
    Simunek T; Sterba M; Popelova O; Kaiserova H; Potacova A; Adamcova M; Mazurova Y; Ponka P; Gersl V
    Hemoglobin; 2008; 32(1-2):207-15. PubMed ID: 18274998
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Iron chelators of the pyridoxal isonicotinoyl hydrazone class. III. Formation constants with calcium(II), magnesium(II) and zinc(II).
    Richardson DR; Hefter GT; May PM; Webb J; Baker E
    Biol Met; 1989; 2(3):161-7. PubMed ID: 2490071
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Future of toxicology--iron chelators and differing modes of action and toxicity: the changing face of iron chelation therapy.
    Kalinowski DS; Richardson DR
    Chem Res Toxicol; 2007 May; 20(5):715-20. PubMed ID: 17402750
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties.
    Buss JL; Neuzil J; Gellert N; Weber C; Ponka P
    Biochem Pharmacol; 2003 Jan; 65(2):161-72. PubMed ID: 12504792
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Iron chelation by pyridoxal isonicotinoyl hydrazone and analogues in hepatocytes in culture.
    Baker E; Vitolo ML; Webb J
    Biochem Pharmacol; 1985 Sep; 34(17):3011-7. PubMed ID: 4038321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.