BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 9586635)

  • 1. Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis.
    Andrade F; Roy S; Nicholson D; Thornberry N; Rosen A; Casciola-Rosen L
    Immunity; 1998 Apr; 8(4):451-60. PubMed ID: 9586635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.
    Song Q; Burrows SR; Smith G; Lees-Miller SP; Kumar S; Chan DW; Trapani JA; Alnemri E; Litwack G; Lu H; Moss DJ; Jackson S; Lavin MF
    J Exp Med; 1996 Aug; 184(2):619-26. PubMed ID: 8760815
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3.
    Chinnaiyan AM; Hanna WL; Orth K; Duan H; Poirier GG; Froelich CJ; Dixit VM
    Curr Biol; 1996 Jul; 6(7):897-9. PubMed ID: 8805307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.
    Atkinson EA; Barry M; Darmon AJ; Shostak I; Turner PC; Moyer RW; Bleackley RC
    J Biol Chem; 1998 Aug; 273(33):21261-6. PubMed ID: 9694885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.
    Barry M; Heibein JA; Pinkoski MJ; Lee SF; Moyer RW; Green DR; Bleackley RC
    Mol Cell Biol; 2000 Jun; 20(11):3781-94. PubMed ID: 10805722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis.
    Browne KA; Johnstone RW; Jans DA; Trapani JA
    J Biol Chem; 2000 Dec; 275(50):39262-6. PubMed ID: 11050075
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis.
    Zhang D; Beresford PJ; Greenberg AH; Lieberman J
    Proc Natl Acad Sci U S A; 2001 May; 98(10):5746-51. PubMed ID: 11331782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
    Darmon AJ; Nicholson DW; Bleackley RC
    Nature; 1995 Oct; 377(6548):446-8. PubMed ID: 7566124
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NuMA and nuclear lamins behave differently in Fas-mediated apoptosis.
    Taimen P; Kallajoki M
    J Cell Sci; 2003 Feb; 116(Pt 3):571-83. PubMed ID: 12508117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bcl-2 expression in target cells leads to functional inhibition of caspase-3 protease family in human NK and lymphokine-activated killer cell granule-mediated apoptosis.
    Renvoizé C; Roger R; Moulian N; Bertoglio J; Bréard J
    J Immunol; 1997 Jul; 159(1):126-34. PubMed ID: 9200447
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis.
    Hirata H; Takahashi A; Kobayashi S; Yonehara S; Sawai H; Okazaki T; Yamamoto K; Sasada M
    J Exp Med; 1998 Feb; 187(4):587-600. PubMed ID: 9463409
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.
    Shi L; Chen G; MacDonald G; Bergeron L; Li H; Miura M; Rotello RJ; Miller DK; Li P; Seshadri T; Yuan J; Greenberg AH
    Proc Natl Acad Sci U S A; 1996 Oct; 93(20):11002-7. PubMed ID: 8855298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequential activation of three distinct ICE-like activities in Fas-ligated Jurkat cells.
    Greidinger EL; Miller DK; Yamin TT; Casciola-Rosen L; Rosen A
    FEBS Lett; 1996 Jul; 390(3):299-303. PubMed ID: 8706881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis.
    Medema JP; Toes RE; Scaffidi C; Zheng TS; Flavell RA; Melief CJ; Peter ME; Offringa R; Krammer PH
    Eur J Immunol; 1997 Dec; 27(12):3492-8. PubMed ID: 9464839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis.
    Thomas DA; Du C; Xu M; Wang X; Ley TJ
    Immunity; 2000 Jun; 12(6):621-32. PubMed ID: 10894162
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation.
    Sharif-Askari E; Alam A; Rhéaume E; Beresford PJ; Scotto C; Sharma K; Lee D; DeWolf WE; Nuttall ME; Lieberman J; Sékaly RP
    EMBO J; 2001 Jun; 20(12):3101-13. PubMed ID: 11406587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase dependence of target cell damage induced by cytotoxic lymphocytes.
    Sarin A; Haddad EK; Henkart PA
    J Immunol; 1998 Sep; 161(6):2810-6. PubMed ID: 9743340
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner.
    Sebbagh M; Hamelin J; Bertoglio J; Solary E; Bréard J
    J Exp Med; 2005 Feb; 201(3):465-71. PubMed ID: 15699075
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.
    Quan LT; Tewari M; O'Rourke K; Dixit V; Snipas SJ; Poirier GG; Ray C; Pickup DJ; Salvesen GS
    Proc Natl Acad Sci U S A; 1996 Mar; 93(5):1972-6. PubMed ID: 8700869
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.
    Galvin JP; Spaeny-Dekking LH; Wang B; Seth P; Hack CE; Froelich CJ
    J Immunol; 1999 May; 162(9):5345-50. PubMed ID: 10228010
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.