146 related articles for article (PubMed ID: 9586962)
1. Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam.
Yang TJ; Shou M; Korzekwa KR; Gonzalez FJ; Gelboin HV; Yang SK
Biochem Pharmacol; 1998 Mar; 55(6):889-96. PubMed ID: 9586962
[TBL] [Abstract][Full Text] [Related]
2. Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone.
Shou M; Korzekwa KR; Brooks EN; Krausz KW; Gonzalez FJ; Gelboin HV
Carcinogenesis; 1997 Jan; 18(1):207-14. PubMed ID: 9054608
[TBL] [Abstract][Full Text] [Related]
3. Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: role of CYP2B6, 2C19 and the 3A subfamily.
Ono S; Hatanaka T; Miyazawa S; Tsutsui M; Aoyama T; Gonzalez FJ; Satoh T
Xenobiotica; 1996 Nov; 26(11):1155-66. PubMed ID: 8948091
[TBL] [Abstract][Full Text] [Related]
4. Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism.
Yang TJ; Krausz KW; Sai Y; Gonzalez FJ; Gelboin HV
Drug Metab Dispos; 1999 Jan; 27(1):102-9. PubMed ID: 9884317
[TBL] [Abstract][Full Text] [Related]
5. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
[TBL] [Abstract][Full Text] [Related]
6. Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
Shou M; Krausz KW; Gonzalez FJ; Gelboin HV
Arch Biochem Biophys; 1996 Apr; 328(1):201-7. PubMed ID: 8638931
[TBL] [Abstract][Full Text] [Related]
7. Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats.
Neville CF; Ninomiya S; Shimada N; Kamataki T; Imaoka S; Funae Y
Biochem Pharmacol; 1993 Jan; 45(1):59-65. PubMed ID: 8424823
[TBL] [Abstract][Full Text] [Related]
8. Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not N-dealkylation of diazepam and temazepam.
Reilly PE; Thompson DA; Mason SR; Hooper WD
Mol Pharmacol; 1990 May; 37(5):767-74. PubMed ID: 1971091
[TBL] [Abstract][Full Text] [Related]
9. 4-Biphenylaldehyde and 9-anthraldehyde: two fluorescent substrates for determining P450 enzyme activities in rat and human.
Marini S; Grasso E; Longo V; Puccini P; Riccardi B; Gervasi PG
Xenobiotica; 2003 Jan; 33(1):1-11. PubMed ID: 12519690
[TBL] [Abstract][Full Text] [Related]
10. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
Marill J; Cresteil T; Lanotte M; Chabot GG
Mol Pharmacol; 2000 Dec; 58(6):1341-8. PubMed ID: 11093772
[TBL] [Abstract][Full Text] [Related]
11. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
Heyn H; White RB; Stevens JC
Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
[TBL] [Abstract][Full Text] [Related]
12. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
Spracklin DK; Thummel KE; Kharasch ED
Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
[TBL] [Abstract][Full Text] [Related]
13. Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms.
Andersson T; Miners JO; Veronese ME; Birkett DJ
Br J Clin Pharmacol; 1994 Aug; 38(2):131-7. PubMed ID: 7981013
[TBL] [Abstract][Full Text] [Related]
14. Differential N-demethylation of l-alpha-acetylmethadol (LAAM) and norLAAM by cytochrome P450s 2B6, 2C18, and 3A4.
Neff JA; Moody DE
Biochem Biophys Res Commun; 2001 Jun; 284(3):751-6. PubMed ID: 11396966
[TBL] [Abstract][Full Text] [Related]
15. Inhibitory monoclonal antibody to human cytochrome P450 2B6.
Yang TJ; Krausz KW; Shou M; Yang SK; Buters JT; Gonzalez FJ; Gelboin HV
Biochem Pharmacol; 1998 May; 55(10):1633-40. PubMed ID: 9633999
[TBL] [Abstract][Full Text] [Related]
16. Metabolism of diazepam in vitro by human liver. Independent variability of N-demethylation and C3-hydroxylation.
Inaba T; Tait A; Nakano M; Mahon WA; Kalow W
Drug Metab Dispos; 1988; 16(4):605-8. PubMed ID: 2903030
[TBL] [Abstract][Full Text] [Related]
17. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles.
Roy P; Yu LJ; Crespi CL; Waxman DJ
Drug Metab Dispos; 1999 Jun; 27(6):655-66. PubMed ID: 10348794
[TBL] [Abstract][Full Text] [Related]
18. The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
Eur Neuropsychopharmacol; 2004 May; 14(3):199-208. PubMed ID: 15056479
[TBL] [Abstract][Full Text] [Related]
19. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.
Yamazaki H; Shaw PM; Guengerich FP; Shimada T
Chem Res Toxicol; 1998 Jun; 11(6):659-65. PubMed ID: 9625734
[TBL] [Abstract][Full Text] [Related]
20. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
Butler AM; Murray M
J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]