BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 9593187)

  • 1. Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond.
    Almog O; Benhar I; Vasmatzis G; Tordova M; Lee B; Pastan I; Gilliland GL
    Proteins; 1998 May; 31(2):128-38. PubMed ID: 9593187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
    Mylvaganam SE; Paterson Y; Getzoff ED
    J Mol Biol; 1998 Aug; 281(2):301-22. PubMed ID: 9698550
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structure of an antitumor C(H)2-domain-deleted humanized antibody.
    Larson SB; Day JS; Glaser S; Braslawsky G; McPherson A
    J Mol Biol; 2005 May; 348(5):1177-90. PubMed ID: 15854653
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design of interchain disulfide bonds in the framework region of the Fv fragment of the monoclonal antibody B3.
    Jung SH; Pastan I; Lee B
    Proteins; 1994 May; 19(1):35-47. PubMed ID: 8066084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model.
    Essen LO; Skerra A
    J Mol Biol; 1994 Apr; 238(2):226-44. PubMed ID: 8158652
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the anti-(carcinoembryonic antigen) single-chain Fv antibody MFE-23 and a model for antigen binding based on intermolecular contacts.
    Boehm MK; Corper AL; Wan T; Sohi MK; Sutton BJ; Thornton JD; Keep PA; Chester KA; Begent RH; Perkins SJ
    Biochem J; 2000 Mar; 346 Pt 2(Pt 2):519-28. PubMed ID: 10677374
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cross-reactive binding of cyclic peptides to an anti-TGFalpha antibody Fab fragment: an X-ray structural and thermodynamic analysis.
    Hahn M; Winkler D; Welfle K; Misselwitz R; Welfle H; Wessner H; Zahn G; Scholz C; Seifert M; Harkins R; Schneider-Mergener J; Höhne W
    J Mol Biol; 2001 Nov; 314(2):293-309. PubMed ID: 11718562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
    Eigenbrot C; Randal M; Presta L; Carter P; Kossiakoff AA
    J Mol Biol; 1993 Feb; 229(4):969-95. PubMed ID: 8095303
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.
    Covaceuszach S; Cattaneo A; Lamba D
    Proteins; 2005 Feb; 58(3):717-27. PubMed ID: 15625712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
    Guddat LW; Shan L; Broomell C; Ramsland PA; Fan Z; Anchin JM; Linthicum DS; Edmundson AB
    J Mol Biol; 2000 Sep; 302(4):853-72. PubMed ID: 10993728
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
    Chen Y; Wiesmann C; Fuh G; Li B; Christinger HW; McKay P; de Vos AM; Lowman HB
    J Mol Biol; 1999 Nov; 293(4):865-81. PubMed ID: 10543973
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytotoxic and antitumor activity of a recombinant tumor necrosis factor-B1(Fv) fusion protein on LeY antigen-expressing human cancer cells.
    Scherf U; Benhar I; Webber KO; Pastan I; Brinkmann U
    Clin Cancer Res; 1996 Sep; 2(9):1523-31. PubMed ID: 9816329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens.
    Ramsland PA; Farrugia W; Bradford TM; Mark Hogarth P; Scott AM
    J Mol Biol; 2004 Jul; 340(4):809-18. PubMed ID: 15223322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multivalent antibody fragments with high functional affinity for a tumor-associated carbohydrate antigen.
    Rheinnecker M; Hardt C; Ilag LL; Kufer P; Gruber R; Hoess A; Lupas A; Rottenberger C; Plückthun A; Pack P
    J Immunol; 1996 Oct; 157(7):2989-97. PubMed ID: 8816407
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody.
    Nakasako M; Takahashi H; Shimba N; Shimada I; Arata Y
    J Mol Biol; 1999 Aug; 291(1):117-34. PubMed ID: 10438610
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen binding.
    Bhat TN; Bentley GA; Fischmann TO; Boulot G; Poljak RJ
    Nature; 1990 Oct; 347(6292):483-5. PubMed ID: 2215663
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.
    Arevalo JH; Stura EA; Taussig MJ; Wilson IA
    J Mol Biol; 1993 May; 231(1):103-18. PubMed ID: 8496956
    [TBL] [Abstract][Full Text] [Related]  

  • 18. X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65.
    Eigenbrot C; Gonzalez T; Mayeda J; Carter P; Werther W; Hotaling T; Fox J; Kessler J
    Proteins; 1994 Jan; 18(1):49-62. PubMed ID: 7908437
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-ray structure of the uncomplexed anti-tumor antibody BR96 and comparison with its antigen-bound form.
    Sheriff S; Chang CY; Jeffrey PD; Bajorath J
    J Mol Biol; 1996 Jun; 259(5):938-46. PubMed ID: 8683596
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Refined structure of an intact IgG2a monoclonal antibody.
    Harris LJ; Larson SB; Hasel KW; McPherson A
    Biochemistry; 1997 Feb; 36(7):1581-97. PubMed ID: 9048542
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.