BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 9598804)

  • 1. Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets.
    Walker GJ; Flores JF; Glendening JM; Lin AH; Markl ID; Fountain JW
    Genes Chromosomes Cancer; 1998 Jun; 22(2):157-63. PubMed ID: 9598804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Association of CDKN2A(p16)/CDKN2B(p15) alterations and homozygous chromosome arm 9p deletions in human lung carcinoma.
    Hamada K; Kohno T; Kawanishi M; Ohwada S; Yokota J
    Genes Chromosomes Cancer; 1998 Jul; 22(3):232-40. PubMed ID: 9624535
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma.
    Flores JF; Walker GJ; Glendening JM; Haluska FG; Castresana JS; Rubio MP; Pastorfide GC; Boyer LA; Kao WH; Bulyk ML; Barnhill RL; Hayward NK; Housman DE; Fountain JW
    Cancer Res; 1996 Nov; 56(21):5023-32. PubMed ID: 8895759
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.
    Fuxe J; Akusjärvi G; Goike HM; Roos G; Collins VP; Pettersson RF
    Cell Growth Differ; 2000 Jul; 11(7):373-84. PubMed ID: 10939591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancers.
    Suzuki H; Zhou X; Yin J; Lei J; Jiang HY; Suzuki Y; Chan T; Hannon GJ; Mergner WJ; Abraham JM
    Hum Mol Genet; 1995 Oct; 4(10):1883-7. PubMed ID: 8595411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alterations of the tumor suppressor genes CDKN2A (p16(INK4a)), p14(ARF), CDKN2B (p15(INK4b)), and CDKN2C (p18(INK4c)) in atypical and anaplastic meningiomas.
    Boström J; Meyer-Puttlitz B; Wolter M; Blaschke B; Weber RG; Lichter P; Ichimura K; Collins VP; Reifenberger G
    Am J Pathol; 2001 Aug; 159(2):661-9. PubMed ID: 11485924
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fine-mapping loss of gene architecture at the CDKN2B (p15INK4b), CDKN2A (p14ARF, p16INK4a), and MTAP genes in head and neck squamous cell carcinoma.
    Worsham MJ; Chen KM; Tiwari N; Pals G; Schouten JP; Sethi S; Benninger MS
    Arch Otolaryngol Head Neck Surg; 2006 Apr; 132(4):409-15. PubMed ID: 16618910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines.
    Zhou X; Suzuki H; Shimada Y; Imamura M; Yin J; Jiang HY; Tarmin L; Abraham JM; Meltzer SJ
    Genes Chromosomes Cancer; 1995 Aug; 13(4):285-90. PubMed ID: 7547637
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CDKN2A/p16 is inactivated in most melanoma cell lines.
    Castellano M; Pollock PM; Walters MK; Sparrow LE; Down LM; Gabrielli BG; Parsons PG; Hayward NK
    Cancer Res; 1997 Nov; 57(21):4868-75. PubMed ID: 9354451
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of evidence for mutations or deletions in the CDKN2A/p16 and CDKN2B/p15 genes of Brazilian neuroblastoma patients.
    Bassi CL; Martelli L; Cipolotti R; Scrideli CA; Defávery R; Tone LG
    Braz J Med Biol Res; 2004 Nov; 37(11):1683-7. PubMed ID: 15517085
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Screening of germline mutations in the CDKN2A and CDKN2B genes in Swedish families with hereditary cutaneous melanoma.
    Platz A; Hansson J; Månsson-Brahme E; Lagerlof B; Linder S; Lundqvist E; Sevigny P; Inganäs M; Ringborg U
    J Natl Cancer Inst; 1997 May; 89(10):697-702. PubMed ID: 9168184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
    Thompson PM; Maris JM; Hogarty MD; Seeger RC; Reynolds CP; Brodeur GM; White PS
    Cancer Res; 2001 Jan; 61(2):679-86. PubMed ID: 11212268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A single nucleotide polymorphism in the 3'untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare.
    Kumar R; Smeds J; Berggren P; Straume O; Rozell BL; Akslen LA; Hemminki K
    Int J Cancer; 2001 Nov; 95(6):388-93. PubMed ID: 11668523
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The 9p21 region in bladder cancer cell lines: large homozygous deletion inactivate the CDKN2, CDKN2B and MTAP genes.
    Stadler WM; Olopade OI
    Urol Res; 1996; 24(4):239-44. PubMed ID: 8873383
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic and epigenetic alterations of the cyclin-dependent kinase inhibitors p15INK4b and p16INK4a in human thyroid carcinoma cell lines and primary thyroid carcinomas.
    Elisei R; Shiohara M; Koeffler HP; Fagin JA
    Cancer; 1998 Nov; 83(10):2185-93. PubMed ID: 9827724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Homozygous loss of the p15INK4B gene (and not the p16INK4 gene) during tumor progression in a sporadic melanoma patient.
    Glendening JM; Flores JF; Walker GJ; Stone S; Albino AP; Fountain JW
    Cancer Res; 1995 Dec; 55(23):5531-5. PubMed ID: 7585628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas.
    Maelandsmo GM; Flørenes VA; Hovig E; Oyjord T; Engebraaten O; Holm R; Børresen AL; Fodstad O
    Br J Cancer; 1996 Apr; 73(8):909-16. PubMed ID: 8611425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Infrequent mutations and no methylation of CDKN2A (P16/MTS1) and CDKN2B (p15/MTS2) in hepatocellular carcinoma in Taiwan.
    Lin YW; Chen CH; Huang GT; Lee PH; Wang JT; Chen DS; Lu FJ; Sheu JC
    Eur J Cancer; 1998 Oct; 34(11):1789-95. PubMed ID: 9893670
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia.
    Guo SX; Taki T; Ohnishi H; Piao HY; Tabuchi K; Bessho F; Hanada R; Yanagisawa M; Hayashi Y
    Leuk Res; 2000 Jan; 24(1):39-46. PubMed ID: 10634644
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma.
    Sonoda Y; Yoshimoto T; Sekiya T
    Oncogene; 1995 Nov; 11(10):2145-9. PubMed ID: 7478535
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.