These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 9600848)

  • 1. Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105.
    Johansson AS; Stenberg G; Widersten M; Mannervik B
    J Mol Biol; 1998 May; 278(3):687-98. PubMed ID: 9600848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
    Lo Bello M; Oakley AJ; Battistoni A; Mazzetti AP; Nuccetelli M; Mazzarese G; Rossjohn J; Parker MW; Ricci G
    Biochemistry; 1997 May; 36(20):6207-17. PubMed ID: 9166793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions.
    Hansson LO; Widersten M; Mannervik B
    Biochemistry; 1997 Sep; 36(37):11252-60. PubMed ID: 9287168
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of the carboxyl groups of glutathione in the catalytic mechanism of human glutathione transferase A1-1.
    Widersten M; Björnestedt R; Mannervik B
    Biochemistry; 1996 Jun; 35(24):7731-42. PubMed ID: 8672473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Communication between the two active sites of glutathione S-transferase A1-1, probed using wild-type-mutant heterodimers.
    Misquitta SA; Colman RF
    Biochemistry; 2005 Jun; 44(24):8608-19. PubMed ID: 15952767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functions of His107 in the catalytic mechanism of human glutathione S-transferase hGSTM1a-1a.
    Patskovsky YV; Patskovska LN; Listowsky I
    Biochemistry; 1999 Jan; 38(4):1193-202. PubMed ID: 9930979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X; O'Donnell R; Srivastava SK; Xia H; Zimniak P; Nanduri B; Bleicher RJ; Awasthi S; Awasthi YC; Ji X; Singh SV
    Biochem Biophys Res Commun; 1997 Jun; 235(2):424-8. PubMed ID: 9199210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arginine 15 stabilizes an S(N)Ar reaction transition state and the binding of anionic ligands at the active site of human glutathione transferase A1-1.
    Gildenhuys S; Dobreva M; Kinsley N; Sayed Y; Burke J; Pelly S; Gordon GP; Sayed M; Sewell T; Dirr HW
    Biophys Chem; 2010 Feb; 146(2-3):118-25. PubMed ID: 19959275
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Subunit interface residues of glutathione S-transferase A1-1 that are important in the monomer-dimer equilibrium.
    Vargo MA; Nguyen L; Colman RF
    Biochemistry; 2004 Mar; 43(12):3327-35. PubMed ID: 15035604
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosine 50 at the subunit interface of dimeric human glutathione transferase P1-1 is a structural key residue for modulating protein stability and catalytic function.
    Stenberg G; Abdalla AM; Mannervik B
    Biochem Biophys Res Commun; 2000 Apr; 271(1):59-63. PubMed ID: 10777681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineering the xenobiotic substrate specificity of maize glutathione S-transferase I.
    Labrou NE; Kotzia GA; Clonis YD
    Protein Eng Des Sel; 2004 Oct; 17(10):741-8. PubMed ID: 15556969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
    Patskovsky Y; Patskovska L; Almo SC; Listowsky I
    Biochemistry; 2006 Mar; 45(12):3852-62. PubMed ID: 16548513
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of bromosulphophthalein binding to human glutathione S-transferase A1-1: thermodynamics and inhibition kinetics.
    Kolobe D; Sayed Y; Dirr HW
    Biochem J; 2004 Sep; 382(Pt 2):703-9. PubMed ID: 15147239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer.
    Gustafsson A; Nilsson LO; Mannervik B
    J Mol Biol; 2002 Feb; 316(2):395-406. PubMed ID: 11851347
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different roles of functional residues in the hydrophobic binding site of two sweet orange tau glutathione S-transferases.
    Lo Piero AR; Mercurio V; Puglisi I; Petrone G
    FEBS J; 2010 Jan; 277(1):255-62. PubMed ID: 19954490
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Shifting substrate specificity of human glutathione transferase (from class Pi to class alpha) by a single point mutation.
    Nuccetelli M; Mazzetti AP; Rossjohn J; Parker MW; Board P; Caccuri AM; Federici G; Ricci G; Lo Bello M
    Biochem Biophys Res Commun; 1998 Nov; 252(1):184-9. PubMed ID: 9813167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stopped-flow kinetic analysis of the ligand-induced coil-helix transition in glutathione S-transferase A1-1: evidence for a persistent denatured state.
    Nieslanik BS; Dabrowski MJ; Lyon RP; Atkins WM
    Biochemistry; 1999 May; 38(21):6971-80. PubMed ID: 10346919
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular characterization of a glutathione transferase from Pinus tabulaeformis (Pinaceae).
    Zeng QY; Lu H; Wang XR
    Biochimie; 2005 May; 87(5):445-55. PubMed ID: 15820751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants.
    Parker LJ; Ciccone S; Italiano LC; Primavera A; Oakley AJ; Morton CJ; Hancock NC; Bello ML; Parker MW
    J Mol Biol; 2008 Jun; 380(1):131-44. PubMed ID: 18511072
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1.
    Ji X; Blaszczyk J; Xiao B; O'Donnell R; Hu X; Herzog C; Singh SV; Zimniak P
    Biochemistry; 1999 Aug; 38(32):10231-8. PubMed ID: 10441116
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.