286 related articles for article (PubMed ID: 9603976)
1. Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Canard B; Sarfati SR; Richardson CC
J Biol Chem; 1998 Jun; 273(23):14596-604. PubMed ID: 9603976
[TBL] [Abstract][Full Text] [Related]
2. The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Selmi B; Deval J; Alvarez K; Boretto J; Sarfati S; Guerreiro C; Canard B
J Biol Chem; 2003 Oct; 278(42):40464-72. PubMed ID: 12902345
[TBL] [Abstract][Full Text] [Related]
3. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
4. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Apr; 76(7):3248-56. PubMed ID: 11884549
[TBL] [Abstract][Full Text] [Related]
5. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
6. Implication of the tRNA initiation step for human immunodeficiency virus type 1 reverse transcriptase in the mechanism of 3'-azido-3'-deoxythymidine (AZT) resistance.
Vaccaro JA; Anderson KS
Biochemistry; 1998 Oct; 37(40):14189-94. PubMed ID: 9760256
[TBL] [Abstract][Full Text] [Related]
7. Human immunodeficiency virus type 1 reverse transcriptase. 3'-Azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer.
Jaju M; Beard WA; Wilson SH
J Biol Chem; 1995 Apr; 270(17):9740-7. PubMed ID: 7537269
[TBL] [Abstract][Full Text] [Related]
8. Sensitivity of HIV-1 reverse transcriptase and its mutants to inhibition by azidothymidine triphosphate.
Carroll SS; Geib J; Olsen DB; Stahlhut M; Shafer JA; Kuo LC
Biochemistry; 1994 Mar; 33(8):2113-20. PubMed ID: 7509634
[TBL] [Abstract][Full Text] [Related]
9. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
[TBL] [Abstract][Full Text] [Related]
10. Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate.
Odriozola L; Cruchaga C; Andréola M; Dollé V; Nguyen CH; Tarrago-Litvak L; Pérez-Mediavilla A; Martínez-Irujo JJ
J Biol Chem; 2003 Oct; 278(43):42710-6. PubMed ID: 12917424
[TBL] [Abstract][Full Text] [Related]
11. Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.
Meyer PR; Matsuura SE; Schinazi RF; So AG; Scott WA
Antimicrob Agents Chemother; 2000 Dec; 44(12):3465-72. PubMed ID: 11083661
[TBL] [Abstract][Full Text] [Related]
12. Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase.
Arion D; Kaushik N; McCormick S; Borkow G; Parniak MA
Biochemistry; 1998 Nov; 37(45):15908-17. PubMed ID: 9843396
[TBL] [Abstract][Full Text] [Related]
13. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
[TBL] [Abstract][Full Text] [Related]
14. Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate.
Reardon JE; Miller WH
J Biol Chem; 1990 Nov; 265(33):20302-7. PubMed ID: 1700787
[TBL] [Abstract][Full Text] [Related]
15. A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase.
Meyer PR; Matsuura SE; Mian AM; So AG; Scott WA
Mol Cell; 1999 Jul; 4(1):35-43. PubMed ID: 10445025
[TBL] [Abstract][Full Text] [Related]
16. Structural basis of HIV-1 resistance to AZT by excision.
Tu X; Das K; Han Q; Bauman JD; Clark AD; Hou X; Frenkel YV; Gaffney BL; Jones RA; Boyer PL; Hughes SH; Sarafianos SG; Arnold E
Nat Struct Mol Biol; 2010 Oct; 17(10):1202-9. PubMed ID: 20852643
[TBL] [Abstract][Full Text] [Related]
17. Relationship between 3'-azido-3'-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase.
Meyer PR; Matsuura SE; Zonarich D; Chopra RR; Pendarvis E; Bazmi HZ; Mellors JW; Scott WA
J Virol; 2003 Jun; 77(11):6127-37. PubMed ID: 12743270
[TBL] [Abstract][Full Text] [Related]
18. Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site.
Klarmann GJ; Smith RA; Schinazi RF; North TW; Preston BD
J Biol Chem; 2000 Jan; 275(1):359-66. PubMed ID: 10617626
[TBL] [Abstract][Full Text] [Related]
19. Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.
Krebs R; Immendörfer U; Thrall SH; Wöhrl BM; Goody RS
Biochemistry; 1997 Aug; 36(33):10292-300. PubMed ID: 9254628
[TBL] [Abstract][Full Text] [Related]
20. Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors.
Mas A; Vázquez-Alvarez BM; Domingo E; Menéndez-Arias L
J Mol Biol; 2002 Oct; 323(2):181-97. PubMed ID: 12381314
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]