160 related articles for article (PubMed ID: 9604881)
1. MODY1 mutation Q268X in hepatocyte nuclear factor 4alpha allows for dimerization in solution but causes abnormal subcellular localization.
Sladek FM; Dallas-Yang Q; Nepomuceno L
Diabetes; 1998 Jun; 47(6):985-90. PubMed ID: 9604881
[TBL] [Abstract][Full Text] [Related]
2. Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.
Shih DQ; Dansky HM; Fleisher M; Assmann G; Fajans SS; Stoffel M
Diabetes; 2000 May; 49(5):832-7. PubMed ID: 10905494
[TBL] [Abstract][Full Text] [Related]
3. Functional characterization of the MODY1 gene mutations HNF4(R127W), HNF4(V255M), and HNF4(E276Q).
Navas MA; Munoz-Elias EJ; Kim J; Shih D; Stoffel M
Diabetes; 1999 Jul; 48(7):1459-65. PubMed ID: 10389854
[TBL] [Abstract][Full Text] [Related]
4. Functional study of the E276Q mutant hepatocyte nuclear factor-4alpha found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter.
Suaud L; Hemimou Y; Formstecher P; Laine B
Diabetes; 1999 May; 48(5):1162-7. PubMed ID: 10331424
[TBL] [Abstract][Full Text] [Related]
5. Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha.
Bogan AA; Dallas-Yang Q; Ruse MD; Maeda Y; Jiang G; Nepomuceno L; Scanlan TS; Cohen FE; Sladek FM
J Mol Biol; 2000 Sep; 302(4):831-51. PubMed ID: 10993727
[TBL] [Abstract][Full Text] [Related]
6. R127W-HNF-4alpha is a loss of function mutation but not a rare polymorphism and causes Type II diabetes in a Japanese family with MODY1.
Yang Q; Yamagata K; Yamamoto K; Cao Y; Miyagawa J; Fukamizu A; Hanafusa T; Matsuzawa Y
Diabetologia; 2000 Apr; 43(4):520-4. PubMed ID: 10819248
[TBL] [Abstract][Full Text] [Related]
7. Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians.
Baier LJ; Permana PA; Traurig M; Dobberfuhl A; Wiedrich C; Sutherland J; Thuillez P; Luczy-Bachman G; Hara M; Horikawa Y; Hinokio Y; Hanson RL; Bogardus C
Diabetes Care; 2000 Mar; 23(3):302-4. PubMed ID: 10868855
[TBL] [Abstract][Full Text] [Related]
8. A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young.
Thomas H; Jaschkowitz K; Bulman M; Frayling TM; Mitchell SM; Roosen S; Lingott-Frieg A; Tack CJ; Ellard S; Ryffel GU; Hattersley AT
Hum Mol Genet; 2001 Sep; 10(19):2089-97. PubMed ID: 11590126
[TBL] [Abstract][Full Text] [Related]
9. Rescue of MODY-1 by agonist ligands of hepatocyte nuclear factor-4alpha.
Hertz R; Ben-Haim N; Petrescu AD; Kalderon B; Berman I; Eldad N; Schroeder F; Bar-Tana J
J Biol Chem; 2003 Jun; 278(25):22578-85. PubMed ID: 12697772
[TBL] [Abstract][Full Text] [Related]
10. Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
Lindner T; Gragnoli C; Furuta H; Cockburn BN; Petzold C; Rietzsch H; Weiss U; Schulze J; Bell GI
J Clin Invest; 1997 Sep; 100(6):1400-5. PubMed ID: 9294105
[TBL] [Abstract][Full Text] [Related]
11. Naturally occurring mutations in the human HNF4alpha gene impair the function of the transcription factor to a varying degree.
Lausen J; Thomas H; Lemm I; Bulman M; Borgschulze M; Lingott A; Hattersley AT; Ryffel GU
Nucleic Acids Res; 2000 Jan; 28(2):430-7. PubMed ID: 10606640
[TBL] [Abstract][Full Text] [Related]
12. Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.
Laine B; Eeckhoute J; Suaud L; Briche I; Furuta H; Bell GI; Formstecher P
FEBS Lett; 2000 Aug; 479(1-2):41-5. PubMed ID: 10940385
[TBL] [Abstract][Full Text] [Related]
13. A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus.
Hani EH; Suaud L; Boutin P; Chèvre JC; Durand E; Philippi A; Demenais F; Vionnet N; Furuta H; Velho G; Bell GI; Laine B; Froguel P
J Clin Invest; 1998 Feb; 101(3):521-6. PubMed ID: 9449683
[TBL] [Abstract][Full Text] [Related]
14. Thyroid hormone receptor interacting protein 3 (trip3) is a novel coactivator of hepatocyte nuclear factor-4alpha.
Iwahashi H; Yamagata K; Yoshiuchi I; Terasaki J; Yang Q; Fukui K; Ihara A; Zhu Q; Asakura T; Cao Y; Imagawa A; Namba M; Hanafusa T; Miyagawa J; Matsuzawa Y
Diabetes; 2002 Apr; 51(4):910-4. PubMed ID: 11916906
[TBL] [Abstract][Full Text] [Related]
15. Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.
Hatzis P; Talianidis I
Mol Cell Biol; 2001 Nov; 21(21):7320-30. PubMed ID: 11585914
[TBL] [Abstract][Full Text] [Related]
16. A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young.
Møller AM; Dalgaard LT; Ambye L; Hansen L; Schmitz O; Hansen T; Pedersen O
J Clin Endocrinol Metab; 1999 Jan; 84(1):367-9. PubMed ID: 9920109
[TBL] [Abstract][Full Text] [Related]
17. T130I mutation in HNF-4alpha gene is a loss-of-function mutation in hepatocytes and is associated with late-onset Type 2 diabetes mellitus in Japanese subjects.
Zhu Q; Yamagata K; Miura A; Shihara N; Horikawa Y; Takeda J; Miyagawa J; Matsuzawa Y
Diabetologia; 2003 Apr; 46(4):567-73. PubMed ID: 12669197
[TBL] [Abstract][Full Text] [Related]
18. Identification of new mutations in the hepatocyte nuclear factor 4alpha gene among families with early onset Type 2 diabetes mellitus.
Malecki MT; Yang Y; Antonellis A; Curtis S; Warram JH; Krolewski AS
Diabet Med; 1999 Mar; 16(3):193-200. PubMed ID: 10227563
[TBL] [Abstract][Full Text] [Related]
19. Critical role of residues defining the ligand binding pocket in hepatocyte nuclear factor-4alpha.
Aggelidou E; Iordanidou P; Tsantili P; Papadopoulos G; Hadzopoulou-Cladaras M
J Biol Chem; 2004 Jul; 279(29):30680-8. PubMed ID: 15123688
[TBL] [Abstract][Full Text] [Related]
20. Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene.
Ilag LL; Tabaei BP; Herman WH; Zawacki CM; D'Souza E; Bell GI; Fajans SS
Diabetes; 2000 Jun; 49(6):961-8. PubMed ID: 10866048
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
