284 related articles for article (PubMed ID: 9611256)
1. The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase.
Rezende LF; Drosopoulos WC; Prasad VR
Nucleic Acids Res; 1998 Jun; 26(12):3066-72. PubMed ID: 9611256
[TBL] [Abstract][Full Text] [Related]
2. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
[TBL] [Abstract][Full Text] [Related]
3. The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency.
Hamburgh ME; Drosopoulos WC; Prasad VR
Nucleic Acids Res; 1998 Oct; 26(19):4389-94. PubMed ID: 9742239
[TBL] [Abstract][Full Text] [Related]
4. Increased misincorporation fidelity observed for nucleoside analog resistance mutations M184V and E89G in human immunodeficiency virus type 1 reverse transcriptase does not correlate with the overall error rate measured in vitro.
Drosopoulos WC; Prasad VR
J Virol; 1998 May; 72(5):4224-30. PubMed ID: 9557711
[TBL] [Abstract][Full Text] [Related]
5. Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage.
Jamburuthugoda VK; Santos-Velazquez JM; Skasko M; Operario DJ; Purohit V; Chugh P; Szymanski EA; Wedekind JE; Bambara RA; Kim B
J Biol Chem; 2008 Apr; 283(14):9206-16. PubMed ID: 18218633
[TBL] [Abstract][Full Text] [Related]
6. Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1.
Hsu M; Inouye P; Rezende L; Richard N; Li Z; Prasad VR; Wainberg MA
Nucleic Acids Res; 1997 Nov; 25(22):4532-6. PubMed ID: 9358162
[TBL] [Abstract][Full Text] [Related]
7. The impact of multidideoxynucleoside resistance-conferring mutations in human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and error specificity.
Rezende LF; Curr K; Ueno T; Mitsuya H; Prasad VR
J Virol; 1998 Apr; 72(4):2890-5. PubMed ID: 9525609
[TBL] [Abstract][Full Text] [Related]
8. Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids.
Sarafianos SG; Das K; Clark AD; Ding J; Boyer PL; Hughes SH; Arnold E
Proc Natl Acad Sci U S A; 1999 Aug; 96(18):10027-32. PubMed ID: 10468556
[TBL] [Abstract][Full Text] [Related]
9. A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
Weiss KK; Chen R; Skasko M; Reynolds HM; Lee K; Bambara RA; Mansky LM; Kim B
Biochemistry; 2004 Apr; 43(15):4490-500. PubMed ID: 15078095
[TBL] [Abstract][Full Text] [Related]
10. The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis.
Götte M; Arion D; Parniak MA; Wainberg MA
J Virol; 2000 Apr; 74(8):3579-85. PubMed ID: 10729133
[TBL] [Abstract][Full Text] [Related]
11. Interaction of reverse transcriptase (RT) mutations conferring resistance to lamivudine and etravirine: effects on fitness and RT activity of human immunodeficiency virus type 1.
Hu Z; Kuritzkes DR
J Virol; 2011 Nov; 85(21):11309-14. PubMed ID: 21849432
[TBL] [Abstract][Full Text] [Related]
12. Subunit-selective mutational analysis and tissue culture evaluations of the interactions of the E138K and M184I mutations in HIV-1 reverse transcriptase.
Xu HT; Oliveira M; Quashie PK; McCallum M; Han Y; Quan Y; Brenner BG; Wainberg MA
J Virol; 2012 Aug; 86(16):8422-31. PubMed ID: 22623801
[TBL] [Abstract][Full Text] [Related]
13. Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase.
Shah FS; Curr KA; Hamburgh ME; Parniak M; Mitsuya H; Arnez JG; Prasad VR
J Biol Chem; 2000 Sep; 275(35):27037-44. PubMed ID: 10833521
[TBL] [Abstract][Full Text] [Related]
14. Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase.
Feng JY; Anderson KS
Biochemistry; 1999 Jul; 38(29):9440-8. PubMed ID: 10413520
[TBL] [Abstract][Full Text] [Related]
15. Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC-resistant HIV-1 reverse transcriptase.
Wainberg MA; Hsu M; Gu Z; Borkow G; Parniak MA
AIDS; 1996 Dec; 10 Suppl 5():S3-10. PubMed ID: 9030390
[TBL] [Abstract][Full Text] [Related]
16. Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.
Krebs R; Immendörfer U; Thrall SH; Wöhrl BM; Goody RS
Biochemistry; 1997 Aug; 36(33):10292-300. PubMed ID: 9254628
[TBL] [Abstract][Full Text] [Related]
17. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.
Back NK; Nijhuis M; Keulen W; Boucher CA; Oude Essink BO; van Kuilenburg AB; van Gennip AH; Berkhout B
EMBO J; 1996 Aug; 15(15):4040-9. PubMed ID: 8670908
[TBL] [Abstract][Full Text] [Related]
18. Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase.
Oude Essink BB; Back NK; Berkhout B
Nucleic Acids Res; 1997 Aug; 25(16):3212-7. PubMed ID: 9241233
[TBL] [Abstract][Full Text] [Related]
19. Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase.
Wainberg MA; Drosopoulos WC; Salomon H; Hsu M; Borkow G; Parniak M; Gu Z; Song Q; Manne J; Islam S; Castriota G; Prasad VR
Science; 1996 Mar; 271(5253):1282-5. PubMed ID: 8638110
[TBL] [Abstract][Full Text] [Related]
20. Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates.
Quan Y; Gu Z; Li X; Liang C; Parniak MA; Wainberg MA
J Mol Biol; 1998 Mar; 277(2):237-47. PubMed ID: 9514745
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
