106 related articles for article (PubMed ID: 9618436)
1. Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an emopamil-insensitive site of mammalian Delta8-Delta7 sterol isomerase.
Paul R; Silve S; De Nys N; Dupuy PH; Bouteiller CL; Rosenfeld J; Ferrara P; Le Fur G; Casellas P; Loison G
J Pharmacol Exp Ther; 1998 Jun; 285(3):1296-302. PubMed ID: 9618436
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological analysis of sterol delta8-delta7 isomerase proteins with [3H]ifenprodil.
Moebius FF; Reiter RJ; Bermoser K; Glossmann H; Cho SY; Paik YK
Mol Pharmacol; 1998 Sep; 54(3):591-8. PubMed ID: 9730919
[TBL] [Abstract][Full Text] [Related]
3. Yeast sterol C8-C7 isomerase: identification and characterization of a high-affinity binding site for enzyme inhibitors.
Moebius FF; Bermoser K; Reiter RJ; Hanner M; Glossmann H
Biochemistry; 1996 Dec; 35(51):16871-8. PubMed ID: 8988026
[TBL] [Abstract][Full Text] [Related]
4. High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase.
Moebius FF; Reiter RJ; Hanner M; Glossmann H
Br J Pharmacol; 1997 May; 121(1):1-6. PubMed ID: 9146879
[TBL] [Abstract][Full Text] [Related]
5. Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast.
Silve S; Dupuy PH; Labit-Lebouteiller C; Kaghad M; Chalon P; Rahier A; Taton M; Lupker J; Shire D; Loison G
J Biol Chem; 1996 Sep; 271(37):22434-40. PubMed ID: 8798407
[TBL] [Abstract][Full Text] [Related]
6. Cloning of an emopamil-binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity.
Moebius FF; Fitzky BU; Wietzorrek G; Haidekker A; Eder A; Glossmann H
Biochem J; 2003 Aug; 374(Pt 1):229-37. PubMed ID: 12760743
[TBL] [Abstract][Full Text] [Related]
7. Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step.
Labit-Le Bouteiller C; Jamme MF; David M; Silve S; Lanau C; Dhers C; Picard C; Rahier A; Taton M; Loison G; Caput D; Ferrara P; Lupker J
Eur J Biochem; 1998 Sep; 256(2):342-9. PubMed ID: 9760173
[TBL] [Abstract][Full Text] [Related]
8. Molecular characterization of the microsomal tamoxifen binding site.
Kedjouar B; de Médina P; Oulad-Abdelghani M; Payré B; Silvente-Poirot S; Favre G; Faye JC; Poirot M
J Biol Chem; 2004 Aug; 279(32):34048-61. PubMed ID: 15175332
[TBL] [Abstract][Full Text] [Related]
9. Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as Delta(8)-Delta(7) sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity.
Berardi F; Abate C; Ferorelli S; de Robertis AF; Leopoldo M; Colabufo NA; Niso M; Perrone R
J Med Chem; 2008 Dec; 51(23):7523-31. PubMed ID: 19053780
[TBL] [Abstract][Full Text] [Related]
10. The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae.
Silve S; Leplatois P; Josse A; Dupuy PH; Lanau C; Kaghad M; Dhers C; Picard C; Rahier A; Taton M; Le Fur G; Caput D; Ferrara P; Loison G
Mol Cell Biol; 1996 Jun; 16(6):2719-27. PubMed ID: 8649379
[TBL] [Abstract][Full Text] [Related]
11. Isolation and characterization of an Arabidopsis thaliana C-8,7 sterol isomerase: functional and structural similarities to mammalian C-8,7 sterol isomerase/emopamil-binding protein.
Grebenok RJ; Ohnmeiss TE; Yamamoto A; Huntley ED; Galbraith DW; Della Penna D
Plant Mol Biol; 1998 Nov; 38(5):807-15. PubMed ID: 9862498
[TBL] [Abstract][Full Text] [Related]
12. Antiestrogens inhibit the replication of the retroviral Moloney murine leukemia virus in vitro.
Chailleux C; Mesange F; Bayard F; Prats AC; Faye JC
Mol Pharmacol; 1993 Aug; 44(2):324-7. PubMed ID: 7689144
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites.
Berardi F; Loiodice F; Fracchiolla G; Colabufo NA; Perrone R; Tortorella V
J Med Chem; 2003 May; 46(11):2117-24. PubMed ID: 12747784
[TBL] [Abstract][Full Text] [Related]
14. Stereoselective synthesis of a new class of potent and selective inhibitors of human Δ8,7-sterol isomerase.
König M; Müller C; Bracher F
Bioorg Med Chem; 2013 Apr; 21(7):1925-43. PubMed ID: 23433667
[TBL] [Abstract][Full Text] [Related]
15. High-level heterologous expression of the human transmembrane sterol Δ8,Δ7-isomerase in Pichia pastoris.
Cai H; Yao H; Li T; Tang Y; Li D
Protein Expr Purif; 2019 Dec; 164():105463. PubMed ID: 31381990
[TBL] [Abstract][Full Text] [Related]
16. A DNA microarray-based approach to elucidate the effects of the immunosuppressant SR31747A on gene expression in Saccharomyces cerevisiae.
Cinato E; Péléraux A; Silve S; Galiègue S; Dhers C; Picard C; Jbilo O; Loison G; Casellas P
Gene Expr; 2002; 10(5-6):213-30. PubMed ID: 12450214
[TBL] [Abstract][Full Text] [Related]
17. Ligands of the antiestrogen-binding site are able to inhibit virion production of human immunodeficiency virus 1-infected lymphocytes.
Mesange F; Delarue F; Puel J; Bayard F; Faye JC
Mol Pharmacol; 1996 Jul; 50(1):75-9. PubMed ID: 8700122
[TBL] [Abstract][Full Text] [Related]
18. Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase.
Jbilo O; Vidal H; Paul R; De Nys N; Bensaid M; Silve S; Carayon P; Davi D; Galiègue S; Bourrié B; Guillemot JC; Ferrara P; Loison G; Maffrand JP; Le Fur G; Casellas P
J Biol Chem; 1997 Oct; 272(43):27107-15. PubMed ID: 9341151
[TBL] [Abstract][Full Text] [Related]
19. Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Moebius FF; Soellner KE; Fiechtner B; Huck CW; Bonn G; Glossmann H
Biochemistry; 1999 Jan; 38(3):1119-27. PubMed ID: 9894009
[TBL] [Abstract][Full Text] [Related]
20. Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae.
Soustre I; Dupuy PH; Silve S; Karst F; Loison G
FEBS Lett; 2000 Mar; 470(2):102-6. PubMed ID: 10734216
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]