126 related articles for article (PubMed ID: 9620216)
1. 5-fluorouracil/leucovorin-induced inhibition of thymidylate synthase in normal tissues of mouse and man.
van der Wilt CL; van Groeningen CJ; Pinedo HM; Smid K; Hoekman K; Meijer S; Peters GJ
J Cancer Res Clin Oncol; 1997; 123(11-12):595-601. PubMed ID: 9620216
[TBL] [Abstract][Full Text] [Related]
2. Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors.
Van der Wilt CL; Pinedo HM; Smid K; Peters GJ
Cancer Res; 1992 Sep; 52(18):4922-8. PubMed ID: 1516048
[TBL] [Abstract][Full Text] [Related]
3. Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
van der Wilt CL; Pinedo HM; Smid K; Cloos J; Noordhuis P; Peters GJ
Semin Oncol; 1992 Apr; 19(2 Suppl 3):16-25. PubMed ID: 1532671
[TBL] [Abstract][Full Text] [Related]
4. Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells.
Erlichman C; Mitrovski B
Cancer Chemother Pharmacol; 1994; 34(1):51-6. PubMed ID: 8174202
[TBL] [Abstract][Full Text] [Related]
5. The effect of different routes of administration of 5-fluorouracil on thymidylate synthase inhibition in the rat.
van der Wilt CL; Marinelli A; Pinedo HM; Cloos J; Smid K; van de Velde CJ; Peters GJ
Eur J Cancer; 1995; 31A(5):754-60. PubMed ID: 7640050
[TBL] [Abstract][Full Text] [Related]
6. High-dose 5-Fluorouracil with uridine-diphosphoglucose rescue increases thymidylate synthase inhibition but not 5-Fluorouracil incorporation into RNA in murine tumors.
Codacci-Pisanelli G; Van der Wilt CL; Smid K; Noordhuis P; Voorn D; Pinedo HM; Peters GJ
Oncology; 2002; 62(4):363-70. PubMed ID: 12138245
[TBL] [Abstract][Full Text] [Related]
7. Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.
Peters GJ; van der Wilt CL; van Groeningen CJ; Smid K; Meijer S; Pinedo HM
J Clin Oncol; 1994 Oct; 12(10):2035-42. PubMed ID: 7931471
[TBL] [Abstract][Full Text] [Related]
8. Selective protection by uridine of growth inhibition by 5-fluorouracil (5FU) mediated by 5FU incorporation into RNA, but not the thymidylate synthase mediated growth inhibition by 5FU-leucovorin.
Codacci-Pisanelli G; Noordhuis P; van der Wilt CL; Peters GJ
Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):733-9. PubMed ID: 18600533
[TBL] [Abstract][Full Text] [Related]
9. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism.
Peters GJ; Backus HH; Freemantle S; van Triest B; Codacci-Pisanelli G; van der Wilt CL; Smid K; Lunec J; Calvert AH; Marsh S; McLeod HL; Bloemena E; Meijer S; Jansen G; van Groeningen CJ; Pinedo HM
Biochim Biophys Acta; 2002 Jul; 1587(2-3):194-205. PubMed ID: 12084461
[TBL] [Abstract][Full Text] [Related]
10. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
11. Influence of dose of [6RS]leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts.
Houghton JA; Williams LG; Cheshire PJ; Wainer IW; Jadaud P; Houghton PJ
Cancer Res; 1990 Jul; 50(13):3940-6. PubMed ID: 2354443
[TBL] [Abstract][Full Text] [Related]
12. Thymidylate synthase protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil.
Cascinu S; Aschele C; Barni S; Debernardis D; Baldo C; Tunesi G; Catalano V; Staccioli MP; Brenna A; Muretto P; Catalano G
Clin Cancer Res; 1999 Aug; 5(8):1996-9. PubMed ID: 10473077
[TBL] [Abstract][Full Text] [Related]
13. Time course of inhibition of thymidylate synthase in patients treated with fluorouracil and leucovorin.
Peters GJ; van Groeningen CJ; van der Wilt CL; Meijer S; Smid K; Laurensse E; Pinedo HM
Semin Oncol; 1992 Apr; 19(2 Suppl 3):26-35. PubMed ID: 1557655
[TBL] [Abstract][Full Text] [Related]
14. Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase.
Nakamura A; Nakajima G; Okuyama R; Kuramochi H; Kondoh Y; Kanemura T; Takechi T; Yamamoto M; Hayashi K
Gastric Cancer; 2014 Jan; 17(1):188-95. PubMed ID: 23494117
[TBL] [Abstract][Full Text] [Related]
15. Thymidylate synthase and drug resistance.
Peters GJ; van der Wilt CL; van Triest B; Codacci-Pisanelli G; Johnston PG; van Groeningen CJ; Pinedo HM
Eur J Cancer; 1995; 31A(7-8):1299-305. PubMed ID: 7577040
[TBL] [Abstract][Full Text] [Related]
16. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
van der Wilt CL; Backus HH; Smid K; Comijn L; Veerman G; Wouters D; Voorn DA; Priest DG; Bunni MA; Mitchell F; Jackman AL; Jansen G; Peters GJ
Cancer Res; 2001 May; 61(9):3675-81. PubMed ID: 11325838
[TBL] [Abstract][Full Text] [Related]
17. Enhanced inhibition of thymidylate synthase by 5-fluorouracil and [6S]leucovorin combination therapy for breast cancer.
Tominaga T; Toi M; Shirasaka T
Anticancer Res; 1993; 13(6B):2425-7. PubMed ID: 8135478
[TBL] [Abstract][Full Text] [Related]
18. Novel chemical strategies for thymidylate synthase inhibition.
Gmeiner WH
Curr Med Chem; 2005; 12(2):191-202. PubMed ID: 15638735
[TBL] [Abstract][Full Text] [Related]
19. Schedule-dependency of in vivo modulation of 5-fluorouracil by leucovorin and uridine in murine colon carcinoma.
Nadal JC; van Groeningen CJ; Pinedo HM; Peters GJ
Invest New Drugs; 1989 Jul; 7(2-3):163-72. PubMed ID: 2793368
[TBL] [Abstract][Full Text] [Related]
20. Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma.
Peters GJ; Lankelma J; Kok RM; Noordhuis P; van Groeningen CJ; van der Wilt CL; Meyer S; Pinedo HM
Cancer Chemother Pharmacol; 1993; 31(4):269-76. PubMed ID: 8422689
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
