BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 9622070)

  • 1. Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
    Su GH; Hilgers W; Shekher MC; Tang DJ; Yeo CJ; Hruban RH; Kern SE
    Cancer Res; 1998 Jun; 58(11):2339-42. PubMed ID: 9622070
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.
    Teng DH; Perry WL; Hogan JK; Baumgard M; Bell R; Berry S; Davis T; Frank D; Frye C; Hattier T; Hu R; Jammulapati S; Janecki T; Leavitt A; Mitchell JT; Pero R; Sexton D; Schroeder M; Su PH; Swedlund B; Kyriakis JM; Avruch J; Bartel P; Wong AK; Tavtigian SV
    Cancer Res; 1997 Oct; 57(19):4177-82. PubMed ID: 9331070
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.
    Goggins M; Shekher M; Turnacioglu K; Yeo CJ; Hruban RH; Kern SE
    Cancer Res; 1998 Dec; 58(23):5329-32. PubMed ID: 9850059
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted deletion of MKK4 in cancer cells: a detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss.
    Cunningham SC; Gallmeier E; Hucl T; Dezentje DA; Calhoun ES; Falco G; Abdelmohsen K; Gorospe M; Kern SE
    Cancer Res; 2006 Jun; 66(11):5560-4. PubMed ID: 16740690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and mutation analyses of MKK4, a candidate tumour suppressor gene encoded by chromosome 17p, in human gastric adenocarcinoma.
    Chae KS; Ryu BK; Lee MG; Byun DS; Chi SG
    Eur J Cancer; 2002 Oct; 38(15):2048-57. PubMed ID: 12376211
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers.
    Hilgers W; Song JJ; Haye M; Hruban RR; Kern SE; Fearon ER
    Genes Chromosomes Cancer; 2000 Apr; 27(4):353-7. PubMed ID: 10719364
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitogen-activated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human chromosome 17.
    Yoshida BA; Dubauskas Z; Chekmareva MA; Christiano TR; Stadler WM; Rinker-Schaeffer CW
    Cancer Res; 1999 Nov; 59(21):5483-7. PubMed ID: 10554023
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion and mutation analyses of the P16/MTS-1 tumor suppressor gene in human ductal pancreatic cancer reveals a higher frequency of abnormalities in tumor-derived cell lines than in primary ductal adenocarcinomas.
    Huang L; Goodrow TL; Zhang SY; Klein-Szanto AJ; Chang H; Ruggeri BA
    Cancer Res; 1996 Mar; 56(5):1137-41. PubMed ID: 8640773
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers.
    Kim HL; Vander Griend DJ; Yang X; Benson DA; Dubauskas Z; Yoshida BA; Chekmareva MA; Ichikawa Y; Sokoloff MH; Zhan P; Karrison T; Lin A; Stadler WM; Ichikawa T; Rubin MA; Rinker-Schaeffer CW
    Cancer Res; 2001 Apr; 61(7):2833-7. PubMed ID: 11306453
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors.
    Wang L; Pan Y; Dai JL
    Oncogene; 2004 Aug; 23(35):5978-85. PubMed ID: 15184866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutation rate of MAP2K4/MKK4 in breast carcinoma.
    Su GH; Song JJ; Repasky EA; Schutte M; Kern SE
    Hum Mutat; 2002 Jan; 19(1):81. PubMed ID: 11754110
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MAP2K4/MKK4 expression in pancreatic cancer: genetic validation of immunohistochemistry and relationship to disease course.
    Xin W; Yun KJ; Ricci F; Zahurak M; Qiu W; Su GH; Yeo CJ; Hruban RH; Kern SE; Iacobuzio-Donahue CA
    Clin Cancer Res; 2004 Dec; 10(24):8516-20. PubMed ID: 15623633
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disruption of MKK4 signaling reveals its tumor-suppressor role in embryonic stem cells.
    Cazillis M; Bringuier AF; Delautier D; Buisine M; Bernuau D; Gespach C; Groyer A
    Oncogene; 2004 Jun; 23(27):4735-44. PubMed ID: 15122334
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas.
    Hayes GM; Carrigan PE; Miller LJ
    Cancer Res; 2007 Mar; 67(5):2072-80. PubMed ID: 17332336
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.
    Yamada SD; Hickson JA; Hrobowski Y; Vander Griend DJ; Benson D; Montag A; Karrison T; Huo D; Rutgers J; Adams S; Rinker-Schaeffer CW
    Cancer Res; 2002 Nov; 62(22):6717-23. PubMed ID: 12438272
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of mitogen-activated protein kinase kinase 4 in cancer.
    Whitmarsh AJ; Davis RJ
    Oncogene; 2007 May; 26(22):3172-84. PubMed ID: 17496914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.
    Teng DH; Hu R; Lin H; Davis T; Iliev D; Frye C; Swedlund B; Hansen KL; Vinson VL; Gumpper KL; Ellis L; El-Naggar A; Frazier M; Jasser S; Langford LA; Lee J; Mills GB; Pershouse MA; Pollack RE; Tornos C; Troncoso P; Yung WK; Fujii G; Berson A; Steck PA
    Cancer Res; 1997 Dec; 57(23):5221-5. PubMed ID: 9393738
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective activation of tumor-suppressive MAPKP signaling pathway by triptonide effectively inhibits pancreatic cancer cell tumorigenicity and tumor growth.
    Zhang B; Meng M; Xiang S; Cao Z; Xu X; Zhao Z; Zhang T; Chen B; Yang P; Li Y; Zhou Q
    Biochem Pharmacol; 2019 Aug; 166():70-81. PubMed ID: 31075266
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma.
    Caldas C; Hahn SA; da Costa LT; Redston MS; Schutte M; Seymour AB; Weinstein CL; Hruban RH; Yeo CJ; Kern SE
    Nat Genet; 1994 Sep; 8(1):27-32. PubMed ID: 7726912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MTS-1 (CDKN2) tumor suppressor gene deletions are a frequent event in esophagus squamous cancer and pancreatic adenocarcinoma cell lines.
    Liu Q; Yan YX; McClure M; Nakagawa H; Fujimura F; Rustgi AK
    Oncogene; 1995 Feb; 10(3):619-22. PubMed ID: 7845688
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.