BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 9627118)

  • 1. Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay.
    Di Como CJ; Prives C
    Oncogene; 1998 May; 16(19):2527-39. PubMed ID: 9627118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
    Campomenosi P; Monti P; Aprile A; Abbondandolo A; Frebourg T; Gold B; Crook T; Inga A; Resnick MA; Iggo R; Fronza G
    Oncogene; 2001 Jun; 20(27):3573-9. PubMed ID: 11429705
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay.
    Inga A; Monti P; Fronza G; Darden T; Resnick MA
    Oncogene; 2001 Jan; 20(4):501-13. PubMed ID: 11313981
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants.
    Inga A; Resnick MA
    Oncogene; 2001 Jun; 20(26):3409-19. PubMed ID: 11423991
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Restoring wild-type conformation and DNA-binding activity of mutant p53 is insufficient for restoration of transcriptional activity.
    Brazda V; Muller P; Brozkova K; Vojtesek B
    Biochem Biophys Res Commun; 2006 Dec; 351(2):499-506. PubMed ID: 17070499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.
    Takimoto R; El-Deiry WS
    Oncogene; 2000 Mar; 19(14):1735-43. PubMed ID: 10777207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of p53 transactivation through high-affinity binding sites.
    Chumakov AM; Miller CW; Chen DL; Koeffler HP
    Oncogene; 1993 Nov; 8(11):3005-11. PubMed ID: 8414502
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transactivational and DNA binding abilities of endogenous p53 in p53 mutant cell lines.
    Park DJ; Nakamura H; Chumakov AM; Said JW; Miller CW; Chen DL; Koeffler HP
    Oncogene; 1994 Jul; 9(7):1899-906. PubMed ID: 8208536
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumour p53 mutations exhibit promoter selective dominance over wild type p53.
    Monti P; Campomenosi P; Ciribilli Y; Iannone R; Inga A; Abbondandolo A; Resnick MA; Fronza G
    Oncogene; 2002 Mar; 21(11):1641-8. PubMed ID: 11896595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterogeneity of transcriptional activity of mutant p53 proteins and p53 DNA target sequences.
    Chen JY; Funk WD; Wright WE; Shay JW; Minna JD
    Oncogene; 1993 Aug; 8(8):2159-66. PubMed ID: 8336941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes.
    Lohrum M; Scheidtmann KH
    Oncogene; 1996 Dec; 13(12):2527-39. PubMed ID: 9000127
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations.
    Suad O; Rozenberg H; Brosh R; Diskin-Posner Y; Kessler N; Shimon LJ; Frolow F; Liran A; Rotter V; Shakked Z
    J Mol Biol; 2009 Jan; 385(1):249-65. PubMed ID: 18996393
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The requirement of the carboxyl terminus of p53 for DNA binding and transcriptional activation depends on the specific p53 binding DNA element.
    Zhang W; Guo XY; Deisseroth AB
    Oncogene; 1994 Sep; 9(9):2513-21. PubMed ID: 8058314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain.
    Lányi A; Deb D; Seymour RC; Ludes-Meyers JH; Subler MA; Deb S
    Oncogene; 1998 Jun; 16(24):3169-76. PubMed ID: 9671396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of p53 mutants on wild-type p53-mediated transactivation are cell type dependent.
    Forrester K; Lupold SE; Ott VL; Chay CH; Band V; Wang XW; Harris CC
    Oncogene; 1995 Jun; 10(11):2103-11. PubMed ID: 7784055
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53-mediated transcription induces resistance of DNA to UV inactivation.
    Huang J; Logsdon N; Schmieg FI; Simmons DT
    Oncogene; 1998 Jul; 17(4):401-11. PubMed ID: 9696032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes.
    Thornborrow EC; Patel S; Mastropietro AE; Schwartzfarb EM; Manfredi JJ
    Oncogene; 2002 Feb; 21(7):990-9. PubMed ID: 11850816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reporter gene regulation in Saccharomyces cerevisiae by the human p53 tumor suppressor protein.
    Bitter GA; Schaeffer TN; Ellison AR
    J Mol Microbiol Biotechnol; 2002 Nov; 4(6):539-50. PubMed ID: 12432954
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Use of transcription reporters with novel p53 binding sites to target tumour cells expressing endogenous or virally transduced p53 mutants with altered sequence-specificity.
    Gagnebin J; Kovar H; Kajava AV; Estreicher A; Jug G; Monnier P; Iggo R
    Oncogene; 1998 Feb; 16(5):685-90. PubMed ID: 9482117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant p53 proteins behave in a dominant, negative fashion in vivo.
    Hachiya M; Chumakov A; Miller CW; Akashi M; Said J; Koeffler HP
    Anticancer Res; 1994; 14(5A):1853-9. PubMed ID: 7847818
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.