BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 9632358)

  • 1. Discovery of a novel series of potent and selective substrate-based inhibitors of p60c-src protein tyrosine kinase: conformational and topographical constraints in peptide design.
    Alfaro-Lopez J; Yuan W; Phan BC; Kamath J; Lou Q; Lam KS; Hruby VJ
    J Med Chem; 1998 Jun; 41(13):2252-60. PubMed ID: 9632358
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potent pseudosubstrate-based peptide inhibitors for p60(c-src) protein tyrosine kinase.
    Lou Q; Leftwich ME; McKay RT; Salmon SE; Rychetsky L; Lam KS
    Cancer Res; 1997 May; 57(10):1877-81. PubMed ID: 9157979
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
    Devadas B; Freeman SK; Zupec ME; Lu HF; Nagarajan SR; Kishore NS; Lodge JK; Kuneman DW; McWherter CA; Vinjamoori DV; Getman DP; Gordon JI; Sikorski JA
    J Med Chem; 1997 Aug; 40(16):2609-25. PubMed ID: 9258368
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-(Phenylamino)pyrrolopyrimidines: potent and selective, ATP site directed inhibitors of the EGF-receptor protein tyrosine kinase.
    Traxler PM; Furet P; Mett H; Buchdunger E; Meyer T; Lydon N
    J Med Chem; 1996 Jun; 39(12):2285-92. PubMed ID: 8691423
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of novel tyrosine kinase inhibitors using a pharmacophore model of the ATP-binding site of the EGF-R.
    Traxler P; Furet P; Mett H; Buchdunger E; Meyer T; Lydon N
    J Pharm Belg; 1997; 52(2):88-96. PubMed ID: 9193132
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
    Dalgarno D; Stehle T; Narula S; Schelling P; van Schravendijk MR; Adams S; Andrade L; Keats J; Ram M; Jin L; Grossman T; MacNeil I; Metcalf C; Shakespeare W; Wang Y; Keenan T; Sundaramoorthi R; Bohacek R; Weigele M; Sawyer T
    Chem Biol Drug Des; 2006 Jan; 67(1):46-57. PubMed ID: 16492148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development and characterization of potent and specific peptide inhibitors of p60c-src protein tyrosine kinase using pseudosubstrate-based inhibitor design approach.
    Kamath JR; Liu R; Enstrom AM; Lou Q; Lam KS
    J Pept Res; 2003 Dec; 62(6):260-8. PubMed ID: 14632929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein tyrosine kinases: structure, substrate specificity, and drug discovery.
    al-Obeidi FA; Wu JJ; Lam KS
    Biopolymers; 1998; 47(3):197-223. PubMed ID: 9817025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis for the activity of pp60(c-src) protein tyrosine kinase inhibitors.
    Prabhu NV; Siddiqui SA; McMurray JS; Pettitt BM
    Biopolymers; 2001 Sep; 59(3):167-79. PubMed ID: 11391566
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An exploration of the effects of constraints on the phosphorylation of synthetic protein tyrosine kinase peptide substrates.
    Ruzza P; Donella-Deana A; Calderan A; Filippi B; Cesaro L; Pinna LA; Borin G
    J Pept Sci; 1996; 2(5):325-38. PubMed ID: 9230460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src.
    Nada S; Okada M; MacAuley A; Cooper JA; Nakagawa H
    Nature; 1991 May; 351(6321):69-72. PubMed ID: 1709258
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and anti-tyrosine kinase activity of 3-(substituted-benzylidene)-1, 3-dihydro-indolin derivatives: investigation of their role against p60c-Src receptor tyrosine kinase with the application of receptor docking studies.
    Olgen S; Akaho E; Nebioglu D
    Farmaco; 2005; 60(6-7):497-506. PubMed ID: 15927182
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformationally constrained peptide analogues of pTyr-Glu-Glu-Ile as inhibitors of the Src SH2 domain binding.
    Nam NH; Ye G; Sun G; Parang K
    J Med Chem; 2004 Jun; 47(12):3131-41. PubMed ID: 15163193
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Preparation and characterization of potential antineoplastic agents].
    Orfi L; Wáczek F; Szabó M; Kövesdi I; Mészáros G; Idei M; Horváth A; Hollósy F; Mák M; Szegedi Z; Szende B; Kéri G; Noszál B
    Acta Pharm Hung; 1999 Jun; 69(3):115-22. PubMed ID: 10401154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclic peptides as probes of the substrate binding site of the cytosolic tyrosine kinase, pp60c-src.
    McMurray JS; Budde RJ; Ke S; Obeyesekere NU; Wang W; Ramdas L; Lewis CA
    Arch Biochem Biophys; 1998 Jul; 355(1):124-30. PubMed ID: 9647675
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of efficient pentapeptide substrates for the tyrosine kinase pp60c-src.
    Nair SA; Kim MH; Warren SD; Choi S; Songyang Z; Cantley LC; Hangauer DG
    J Med Chem; 1995 Oct; 38(21):4276-83. PubMed ID: 7473555
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity.
    Grembecka J; Mucha A; Cierpicki T; Kafarski P
    J Med Chem; 2003 Jun; 46(13):2641-55. PubMed ID: 12801228
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and characterization of a substrate selective p38alpha inhibitor.
    Davidson W; Frego L; Peet GW; Kroe RR; Labadia ME; Lukas SM; Snow RJ; Jakes S; Grygon CA; Pargellis C; Werneburg BG
    Biochemistry; 2004 Sep; 43(37):11658-71. PubMed ID: 15362850
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of p56(lck) tyrosine kinase by isothiazolones.
    Trevillyan JM; Chiou XG; Ballaron SJ; Tang QM; Buko A; Sheets MP; Smith ML; Putman CB; Wiedeman P; Tu N; Madar D; Smith HT; Gubbins EJ; Warrior UP; Chen YW; Mollison KW; Faltynek CR; Djurić SW
    Arch Biochem Biophys; 1999 Apr; 364(1):19-29. PubMed ID: 10087161
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge.
    Lukas TJ; Mirzoeva S; Slomczynska U; Watterson DM
    J Med Chem; 1999 Mar; 42(5):910-9. PubMed ID: 10072688
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.